Regulator Genes
Mostrando 1-12 de 2089 artigos, teses e dissertações.
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1. Update on new GH-IGF axis genetic defects
ABSTRACT The somatotropic axis is the main hormonal regulator of growth. Growth hormone (GH), also known as somatotropin, and insulin-like growth factor 1 (IGF-1) are the key components of the somatotropic axis. This axis has been studied for a long time and the knowledge of how some molecules could promote or impair hormones production and action has been g
Arch. Endocrinol. Metab.. Publicado em: 10/01/2020
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2. [PROVISIONAL] Molecular characterization and transcription analysis of DNA methyltransferase genes in tomato (Solanum lycopersicum)
Abstract DNA methylation plays an important role in plant growth and development, gene expression regulation and maintenance of genome stability. However, only little information regarding development- or stress-related DNA methyltransferases (MTases) genes is available in tomato. Here, we report the analysis of nine tomato MTases which were categorized into
Genet. Mol. Biol.. Publicado em: 19/08/2019
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3. Effect of CRABP2 on the proliferation and odontoblastic differentiation of hDPSCs
Abstract: Cellular retinoic acid-binding protein 2 (CRABP2) has been detected in several organs during embryonic development. Recent studies have demonstrated that CRABP2 plays important roles in the retinoic acid, β-catenin and Notch signaling pathways, as well as in the interaction between epithelial and mesenchymal cells, which are important for human de
Braz. oral res.. Publicado em: 18/12/2017
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4. Myostatin promotes distinct responses on protein metabolism of skeletal and cardiac muscle fibers of rodents
Myostatin is a novel negative regulator of skeletal muscle mass. Myostatin expression is also found in heart in a much less extent, but it can be upregulated in pathological conditions, such as heart failure. Myostatin may be involved in inhibiting protein synthesis and/or increasing protein degradation in skeletal and cardiac muscles. Herein, we used cell c
Braz J Med Biol Res. Publicado em: 19/10/2017
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5. Bradyrhizobium elkanii nod regulon: insights through genomic analysis
Abstract A successful symbiotic relationship between soybean [Glycine max (L.) Merr.] and Bradyrhizobium species requires expression of the bacterial structural nod genes that encode for the synthesis of lipochitooligosaccharide nodulation signal molecules, known as Nod factors (NFs). Bradyrhizobium diazoefficiens USDA 110 possesses a wide nodulation gene re
Genet. Mol. Biol.. Publicado em: 31/07/2017
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6. Prevalence of virulence genes in strains of Campylobacter jejuni isolated from human, bovine and broiler
Campylobacter jejuni isolates of different origins (bovine, broiler meat, human) were screened by polymerase chain reaction for the presence of 4 genes cdtB, cst-II, ggt, and virB11, previously linked to virulence such as adherence, invasion, colonization, molecular mimicry, and cytotoxin production. In addition, the isolates were screened for the presence o
Braz. J. Microbiol.. Publicado em: 2013-12
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7. Placental hydroxymethylation vsmethylation at the imprinting control region 2 on chromosome 11p15.5
In addition to methylated cytosines (5-mCs), hydroxymethylcytosines (5-hmCs) are present in CpG dinucleotide-enriched regions and some transcription regulator binding sites. Unlike methylation, hydroxymethylation does not result in silencing of gene expression, and the most commonly used methods to study methylation, such as techniques based on restriction e
Braz J Med Biol Res. Publicado em: 22/10/2013
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8. Comparative analysis of agr groups and virulence genes among subclinical and clinical mastitis Staphylococcus aureus isolates from sheep flocks of the Northeast of Brazil
Staphylococcus aureus is one of the most frequent mastitis causative agents in small ruminants. The expression of most virulence genes of S. aureus is controlled by an accessory gene regulator (agr)locus. This study aimed to ascertain the prevalence of the different agr groups and to evaluate the occurrence of encoding genes for cytotoxin, adhesins and toxin
Braz. J. Microbiol.. Publicado em: 2013
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9. Transcriptional profiling of genes involved in n-hexadecane compounds assimilation in the hydrocarbon degrading Dietzia cinnamea P4 strain
The petroleum-derived degrading Dietzia cinnamea strain P4 recently had its genome sequenced and annotated. This allowed employing the data on genes that are involved in the degradation of n-alkanes. To examine the physiological behavior of strain P4 in the presence of n-alkanes, the strain was grown under varying conditions of pH and temperature. D. cinname
Braz. J. Microbiol.. Publicado em: 2013
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10. Insights into the Melipona scutellaris (Hymenoptera, Apidae, Meliponini) fat body transcriptome
The insect fat body is a multifunctional organ analogous to the vertebrate liver. The fat body is involved in the metabolism of juvenile hormone, regulation of environmental stress, production of immunity regulator-like proteins in cells and protein storage. However, very little is known about the molecular mechanisms involved in fat body physiology in sting
Genet. Mol. Biol.. Publicado em: 2013
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11. Análise da expressão das metaloproteinases 2 e 9 e seus reguladores no câncer de bexiga / Expression of metalloproteinases 2 and 9 and their regulator genes in bladder cancer
Introdução: O Carcinoma Urotelial de Bexiga (CUB) é o segundo tumor urológico mais prevalente no Brasil. Devido ao elevado custo médico no processo que envolve seu diagnóstico, tratamento e seguimento, o CUB é um dos tipos de tumores mais caros para os sistemas de saúde. Embora existam fatores prognósticos definidos, como o estadiamento patológico,
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/01/2012
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12. Effect of ATP and 2-oxoglutarate on the in vitro interaction between the NifA GAF domain and the GlnB protein of Azospirillum brasilense
Azospirillum brasilense is a diazotroph that associates with important agricultural crops and thus has potential to be a nitrogen biofertilizer. The A. brasilense transcription regulator NifA, which seems to be constitutively expressed, activates the transcription of nitrogen fixation genes. It has been suggested that the nitrogen status-signaling protein Gl
Braz J Med Biol Res. Publicado em: 2012-12