Regenerative Therapy
Mostrando 13-24 de 28 artigos, teses e dissertações.
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13. Avaliação da atividade antiofídica do composto p-cumarato de triacontila isolado de Bombacopsis glabra e da toxicidade aguda do extrato de Schizolobium parahyba
The use of plant extracts as antidote against animals venoms is an old practice, mainly envenomations by snakes, besides also may used as supplemental of serum therapy. Snake venoms are a rich mixture of proteins involved in a complex series of events that depends on the synergic action of these molecules. The present study explores the ability of Triacontil
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/07/2011
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14. Construction of a vector for controlled expression of chondroitinase AC for mesenchymal stem cells / Construção de um vetor para expressão controlada de condroitinase AC por células tronco mesenquimais/
Adult mammal axons fail to regenerate when damaged, generating a fundamental problem, inhibiting the recovery of injured central nervous system (CNS). The lack of full regenerative capacity of the injured CNS is due to a glial scar formation on the injury site. The glial scar is formed by astrocytes, oligodendrocyte precursor cells, and microglia, cells that
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/02/2011
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15. Digital subtraction radiographic analysis of the combination of bioabsorbable membrane and bovine morphogenetic protein pool in human periodontal infrabony defects
OBJECTIVES: This study assessed the bone density gain and its relationship with the periodontal clinical parameters in a case series of a regenerative therapy procedure. MATERIAL AND METHODS: Using a split-mouth study design, 10 pairs of infrabony defects from 15 patients were treated with a pool of bovine bone morphogenetic proteins associated with collagen
Journal of Applied Oral Science. Publicado em: 2010-08
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16. Ação da laserterapia de baixa intensidade (830nm) na regeneração muscular de ratos idosos
The elderly still go through physical changes, especially musculoskeletal disorders such as sarcopenia, changes in central and peripheral nervous system, blood hypoperfusion, regenerative changes contributing to atrophy and muscle weakness, undermining the activities of daily living (AVL). The regenerative process happens about the determination, proliferati
Publicado em: 2009
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17. Avaliação de componentes da matriz extracelular na reparação de defeitos de furca classe II após o enxerto de tecido reparativo de alvéolos dentários tratados com fatores de crescimento / Histological study of the healing of class II furcation defects following the graft of healing tissue from extraction sockets previously treated with growth factors.
The tissue from healing extraction sockets is considered an excellent bone grafting material in the therapy of periodontal defects and the association of growth factors to the extraction sockets would increase the regenerative potential of this tissue when utilized as a bone graft. The aim of this investigation was to evaluate qualitatively the healing of ac
Publicado em: 2009
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18. Impaired regeneration of dystrophin-deficient muscle fibers is caused by exhaustion of myogenic cells
Duchenne muscular dystrophy is one of the most devastating myopathies. Muscle fibers undergo necrosis and lose their ability to regenerate, and this may be related to increased interstitial fibrosis or the exhaustion of satellite cells. In this study, we used mdx mice, an animal model of Duchenne muscular dystrophy, to assess whether muscle fibers lose their
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-06
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19. Oesophageal variceal bleeding in Felty's syndrome associated with nodular regenerative hyperplasia.
Four patients with Felty's syndrome developed massive upper gastrointestinal bleeding due to oesophageal varices. The underlying hepatic pathology in all 4 was nodular regenerative hyperplasia. This appears to be a difficult histological diagnosis to make, having been initially reported as normal on percutaneous biopsy or as fibrosis or cirrhosis on wedge bi
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20. Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction
Although clinical trials of autologous whole bone marrow for cardiac repair demonstrate promising results, many practical and mechanistic issues regarding this therapy remain highly controversial. Here, we report the results of a randomized study of bone-marrow-derived mesenchymal stem cells, administered to pigs, which offer several new insights regarding c
National Academy of Sciences.
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21. Cardiac repair and regeneration: the Rubik’s cube of cell therapy for heart disease
Acute ischemic injury and chronic cardiomyopathies damage healthy heart tissue. Dead cells are gradually replaced by a fibrotic scar, which disrupts the normal electromechanical continuum of the ventricular muscle and compromises its pumping capacity. Recent studies in animal models of ischemic cardiomyopathy suggest that transplantation of various stem cell
The Company of Biologists Limited.
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22. Long-term expression of human adenosine deaminase in rhesus monkeys transplanted with retrovirus-infected bone-marrow cells.
Gene transfer into hemopoietic stem cells could offer a lasting cure for a variety of congenital disorders. As a preclinical test for such a gene therapy, rhesus monkeys were transplanted with autologous bone-marrow cells infected with helper-free recombinant retroviruses carrying the human adenosine deaminase gene. The in vivo regenerative capacity of the i
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23. Stem cells and repair of lung injuries
Fueled by the promise of regenerative medicine, currently there is unprecedented interest in stem cells. Furthermore, there have been revolutionary, but somewhat controversial, advances in our understanding of stem cell biology. Stem cells likely play key roles in the repair of diverse lung injuries. However, due to very low rates of cellular proliferation i
BioMed Central.
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24. Prolonged N-acetylcysteine therapy in late acetaminophen poisoning associated with acute liver failure – a need to be more cautious?
Since the 1970s, N-acetylcysteine (NAC) has shown proven efficacy as an antidote for acetaminophen (APAP) poisoning and APAP-induced liver failure for early presenters. The current evidence of benefits of NAC for late presenters is controversial because of the poor understanding of the mechanism of late toxicity. In the previous issue of Critical Care, Yang
BioMed Central.