Redundancy Removal
Mostrando 1-12 de 13 artigos, teses e dissertações.
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1. Redundância funcional em comunidades campestres / Functional redundancy in grassland plant communities
Os campos do Rio Grande do Sul apresentam grande biodiversidade, beleza cênica e um importante recurso para a economia do estado, cuja principal atividade é a pecuária. O manejo inadequado do campo traz conseqüências graves para a diversidade e sustentabilidade desse ecossistema através da perda de espécies promovida pelo pastejo excessivo. Entretanto
Publicado em: 2009
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2. Um algoritmo formal para remoção de redundâncias / A formal algorithm for redundancy removal
Os algoritmos para síntese de circuitos digitais em geral visam a melhoria de uma função de custo composta de quatro critérios: área, desempenho, potência e testabilidade. Normalmente estes algoritmos conseguem uma relação de compromisso para a otimização de dois critérios. Efeitos indesejáveis também podem surgir com a otimização de um destes
Publicado em: 2007
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3. Use of Bmp1/Tll1 Doubly Homozygous Null Mice and Proteomics To Identify and Validate In Vivo Substrates of Bone Morphogenetic Protein 1/Tolloid-Like Metalloproteinases
Bone morphogenetic protein 1 (BMP-1) and mammalian Tolloid (mTLD), two proteinases encoded by Bmp1, provide procollagen C-proteinase (pCP) activity that converts procollagens I to III into the major fibrous components of mammalian extracellular matrix (ECM). Yet, although Bmp1−/− mice have aberrant collagen fibrils, they have residual pCP activity, indic
American Society for Microbiology.
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4. Global genome removal of thymine glycol in Escherichia coli requires endonuclease III but the persistence of processed repair intermediates rather than thymine glycol correlates with cellular sensitivity to high doses of hydrogen peroxide
Using a monoclonal antibody that specifically recognizes thymine glycol (Tg) in DNA, we measured the kinetics of the removal of Tg from the genomes of wild-type and repair gene mutant strains of Escherichia coli treated with hydrogen peroxide. Tg is rapidly and efficiently removed from the total genomes of repair-proficient cells in vivo and the removal of T
Oxford University Press.
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5. Effect of viral RNase H on the avian sarcoma viral genome during early transcription in vitro.
We investigated the influence of viral RNase H on the transcription of the avian sarcoma virus RNA in a virion-associated reaction. The ability of RNase H to degrade the RNA moiety of the initially formed RNA-DNA hybrid at the 5' end of the viral genome was found to be greatly dependent on the exact concentration of nonionic detergent used to activate the re
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6. Specific SR protein-dependent splicing substrates identified through genomic SELEX
The Drosophila pre-mRNA splicing factor B52 (SRp55) is essential for fly development, but splicing of RNAs of specific genes tested previously is normal in B52-null animals, presumably due to partial functional redundancy with other SR proteins. To identify B52-dependent splicing substrates in vivo, we selected genomic sequence fragments whose transcripts bi
Oxford University Press.
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7. Coactivation by OCA-B: Definition of Critical Regions and Synergism with General Cofactors
Molecular dissection of the B-cell-specific transcription coactivator OCA-B has revealed distinct regions important, respectively, for recruitment to immunoglobulin promoters through interaction with octamer-bound Oct-1 and for subsequent coactivator function. Further analysis of general coactivator requirements showed that selective removal of PC4 from the
American Society for Microbiology.
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8. The complete genome sequence of Mycobacterium bovis
Mycobacterium bovis is the causative agent of tuberculosis in a range of animal species and man, with worldwide annual losses to agriculture of $3 billion. The human burden of tuberculosis caused by the bovine tubercle bacillus is still largely unknown. M. bovis was also the progenitor for the M. bovis bacillus Calmette–Guérin vaccine strain, the mos
National Academy of Sciences.
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9. Hox11 paralogous genes are essential for metanephric kidney induction
The mammalian Hox complex is divided into four linkage groups containing 13 sets of paralogous genes. These paralogous genes have retained functional redundancy during evolution. For this reason, loss of only one or two Hox genes within a paralogous group often results in incompletely penetrant phenotypes which are difficult to interpret by molecular analysi
Cold Spring Harbor Laboratory Press.
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10. The Drosophila melanogaster dodo (dod) gene, conserved in humans, is functionally interchangeable with the ESS1 cell division gene of Saccharomyces cerevisiae.
We have sequenced the region of DNA adjacent to and including the flightless (fli) gene of Drosophila melanogaster and molecularly characterized four transcription units within it, which we have named tweety (twe), flightless (fli), dodo (dod), and penguin (pen). We have performed deletion and transgenic analysis to determine the consequences of the quadrupl
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11. An Endoplasmic Reticulum-Bound Ca2+/Mn2+ Pump, ECA1, Supports Plant Growth and Confers Tolerance to Mn2+ Stress1
Plants can grow in soils containing highly variable amounts of mineral nutrients, like Ca2+ and Mn2+, though the mechanisms of adaptation are poorly understood. Here, we report the first genetic study to determine in vivo functions of a Ca2+ pump in plants. Homozygous mutants of Arabidopsis harboring a T-DNA disruption in ECA1 showed a 4-fold reduction in en
American Society of Plant Physiologists.
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12. The Ami-AliA/AliB Permease of Streptococcus pneumoniae Is Involved in Nasopharyngeal Colonization but Not in Invasive Disease
The Ami-AliA/AliB oligopeptide permease is an ATP-binding cassette transporter which is found in Streptococcus pneumoniae and which is involved in nutrient uptake. We investigated the role of the three paralogous oligopeptide-binding lipoproteins AmiA, AliA, and AliB by using murine models of pneumococcal colonization and invasive disease. A series of mutant
American Society for Microbiology.