Recombinant Tsh
Mostrando 1-12 de 21 artigos, teses e dissertações.
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1. Recombinant human TSH versus thyroid hormone withdrawal in adjuvant therapy with radioactive iodine of patients with papillary thyroid carcinoma and clinically apparent lymph node metastases not limited to the central compartment (cN1b)
ABSTRACT Objective To compare the short- and long-term outcomes of adjuvant therapy with radioactive iodine (RAI) preceded by the administration of recombinant human TSH (rhTSH) versus thyroid hormone withdrawal (THW) in patients with papillary thyroid carcinoma and clinically apparent lymph node metastases not limited to the central neck compartment (cN1b
Arch. Endocrinol. Metab.. Publicado em: 13/02/2017
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2. Is 131I ablation necessary for patients with low-risk papillary thyroid carcinoma and slightly elevated stimulated thyroglobulin after thyroidectomy?
ABSTRACT Objective This prospective study evaluated the recurrence rate in low-risk patients with papillary thyroid cancer (PTC) who presented slightly elevated thyroglobulin (Tg) after thyroidectomy and who did not undergo ablation with131I. Subjects and methods The study included 53 low-risk patients (nonaggressive histology; pT1b-3, cN0pNx, M0) with s
Arch. Endocrinol. Metab.. Publicado em: 2016-02
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3. Myxedema madness complicating postoperative follow-up of thyroid cancer
Although hypothyroidism is associated with an increased prevalence of psychiatric manifestations, myxedema madness is rarely observed. We report the case of a 62-year-old woman with no prior history of psychiatric disorders, who presented to the emergency department with psychomotor agitation 6 weeks after total thyroidectomy for papillary thyroid cancer. Se
Arch. Endocrinol. Metab.. Publicado em: 2015-08
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4. Radioiodine plus recombinant human thyrotropin do not cause acute airway compression and are effective in reducing multinodular goiter
Recombinant human thyrotropin (rhTSH) reduces the activity of radioiodine required to treat multinodular goiter (MNG), but acute airway compression can be a life-threatening complication. In this prospective, randomized, double-blind, placebo-controlled study, we assessed the efficacy and safety (including airway compression) of different doses of rhTSH asso
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-03
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5. Multinodular goiter treatment with radioiodine aided by recombinant human TSH in different doses: a randomized, double-blind, placebo-controlled study / Administração prévia do TSH humano recombinante, em diferentes doses, no tratamento do bócio multinodular com iodo radioativo: um estudo randomizado, duplo cego, controlado com placebo
INTRODUÇÃO: Não há tratamento ideal para o bócio multinodular (BMN). A cirurgia é o método mais utilizado, por proporcionar uma redução imediata do volume tiroidiano (VT), dos sintomas compressivos e permitir um diagnóstico histológico definitivo. O iodo radioativo (I¹³¹) é considerado uma excelente opção terapêutica em situações de contr
Publicado em: 2009
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6. Preparação e caracterização das subunidades alfa e beta dos hormônios glicoproteicos humanos recombinantes: foliculotrofina, luteotrofina, tereotrofina e sua comparação com os produtos hipofisários / Preparation and characterization of alpha and beta subunits of recombinant human glycoprotein hormones: follicle-stimulating hormone, luteotropin, thyrotrophin and comparation with pituitary glycoprotein hormones
Neste trabalho é descrito um método prático e eficiente para dissociar, em subunidades α e β, quantidades pequenas (da ordem de microgramas) dos hormônios foliculotrofina (hFSH), luteotrofina (hLH) e tireotrofina (hTSH) humana, nativos e recombinantes. A dissociação destes hormônios foi conseguida incubando-os, durante 16 horas, a 37ºC, co
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/10/2008
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7. Identificação e caracterização de proteinas expressas no espaço intercelular de folhas de Theobroma cacao na interação com Moniliophthora perniciosa / Identification and characterization of proteins expressed in the intercellular space of leves from Theobroma cacao infected by Moniliophthora perniciosa
The invasion of the plant apoplast is a critical phase of the infection for numerous pathogens, including the fungus M. perniciosa (Mp) that remains in the intercellular space at the parasitic stage until about 60 days. Thus, the understanding of plant defenses induced in the apoplasm and the response mechanisms that the pathogens used for bypassing these de
Publicado em: 2008
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8. Screening and functional analysis of thyroglobulin gene mutations de mutações related to congenital goiter and hypothyroidism / Rastreamento e estudo funcional de mutações no gene da tireoglobulina associadas a bócio congênito e hipotireoidismo
Introduction: Congenital hypothyroidism is one of the most common hereditary endocrine disorders, which affects 1:4000 newborns. Congenital hypothyroidism is caused by thyroid gland dysgenesis (80%) or inborn errors of thyroid hormone synthesis (20%). Genetic defects in thyroglobulin, pendrin, thyroperoxidase, dual oxidase 2, simporter sodium/iodine have bee
Publicado em: 2008
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9. Effect of 30 mCi radioiodine on multinodular goiter previously treated with recombinant human thyroid-stimulating hormone
Recombinant human thyroid-stimulating hormone (rhTSH) enhances 131I uptake, permitting a decrease in radiation for the treatment of multinodular goiter (MNG). Our objective was to evaluate the safety and efficacy of a single 0.1-mg dose of rhTSH, followed by 30 mCi 131I, in patients with MNG. Seventeen patients (15 females, 59.0 ± 13.1 years), who had never
Brazilian Journal of Medical and Biological Research. Publicado em: 29/10/2007
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10. Análise da expressão e caracterização funcional da hemaglutinina temperatura sensível de Escherichia coli
Escherichia coli is an important agent of extra-intestinal infections both in humans and animals alike. In poultry, it is responsible for significant economic loss, being known as the pathogenic avian E. coli (APEC); and it causes colibacillosis, which starts as an infection of the respiratory tract evolving to airsacculitis, pericarditis, perihepatitis and
Publicado em: 2006
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11. Estudo dos fatores de virulencia de amostras de Escherichia coli patogenicas de origem aviaria (APEC) / Study of the virulence factors from avian pathogenic Escherichia coli strains (APEC)
Two pathogenic Escherichia coZi strains isolated from avian (APEC) showing c1inical signs of septicemia (817 and 821), and one isolated from avian showing c1inical signs of 8wollen Head 8yndrome (8H8 1 O), were selected from a total of 49 strains belonging to the Laboratory of Bacterial Molecular Biology, after a biological characterization regarding the pre
Publicado em: 2006
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12. From differentiation to proliferation: The secretory amyloid precursor protein as a local mediator of growth in thyroid epithelial cells
In various species, thyrotropin (TSH) is known to stimulate both differentiation and proliferation of thyroid follicle cells. This cell type has also been shown to express members of the Alzheimer amyloid precursor (APP) protein family and to release the secretory N-terminal domain of APP (sAPP) in a TSH-dependent fashion. In this study on binding to the cel
The National Academy of Sciences.