Recombinant Antigen
Mostrando 25-36 de 2217 artigos, teses e dissertações.
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25. Production and diagnostic application of recombinant domain III of West Nile envelope protein in Brazil
INTRODUCTION: West Nile virus (WNV) is a flavivirus with a natural cycle involving mosquitoes and birds. Over the last 11 years, WNV has spread throughout the Americas with the imminent risk of its introduction in Brazil. METHODS: Envelope protein domain III of WNV (rDIII) was bacterially expressed and purified. An enzyme-linked immunosorbent assay with WNV
Rev. Soc. Bras. Med. Trop.. Publicado em: 2013-01
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26. Serologic survey of hantavirus in a rural population from the northern State of Mato Grosso, Brazil
INTRODUCTION: Hantavirus is a genus of ribonucleic acid (RNA) viruses included in the family Bunyaviridae. Hantaviruses are rodent-borne zoonoses that, in the last 18 years, became an emergent public health problem in the Americas, causing a severe cardiopulmonary syndrome. This disease has no specific treatment and has a high case fatality. The transmission
Rev. Soc. Bras. Med. Trop.. Publicado em: 2013-01
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27. Production and characterization of recombinant chimeras C and D of Clostridium botulinum / Produção e caracterização de quimeras recombinantes C e D de Clostridium botulinum
Bovine Botulism is a lethal intoxication caused by the ingestion of the neurotoxins produced by Clostridium botulinum types C and D that inhibit the release of acetylcholine at the neuromuscular junction leading to death by flaccid paralysis. It produces important economic losses, being a major cause of casualties in cattle in several regions of Brazil. The
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/08/2012
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28. EXPRESSION AND CHARACTERIZATION OF A TRUNCATED FORM OF BOVINE HERPESVIRUS TYPE 1 ENVELOPE GLYCOPROTEIN E AND ITS USE IN A DIFFERENTIAL SEROLOGICAL TEST / EXPRESSÃO E CARACTERIZAÇÃO DE UM FRAGMENTO DA GLICOPROTEÍNA E DO HERPESVÍRUS BOVINO TIPO 1 E USO EM UM TESTE SOROLÓGICO DIFERENCIAL
O herpesvírus bovino tipo 1 (BoHV-1) é um vírus de distribuição mundial e produz grandes prejuízos econômicos em rebanhos de corte e de leite. A infecção pelo BoHV-1 produz manifestações respiratórias, reprodutivas e também pode cursar com sinais nervosos. Existem diversos testes laboratoriais capazes de diagnosticar a infecção. Contudo, as t�
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/03/2012
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29. Recombinant vaccines and the development of new vaccine strategies
Vaccines were initially developed on an empirical basis, relying mostly on attenuation or inactivation of pathogens. Advances in immunology, molecular biology, biochemistry, genomics, and proteomics have added new perspectives to the vaccinology field. The use of recombinant proteins allows the targeting of immune responses focused against few protective ant
Braz J Med Biol Res. Publicado em: 2012-12
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30. Synergistic haemolytic activity and its correlation to phospholipase D productivity by Corynebacteruim pseudotuberculosis Egyptian isolates from sheep and buffaloes
Fourteen isolates of Corynebacteruim pseudotuberculosis of them 7 were isolated from sheep with Caseous Lymphadenitis "biotype 1" and 7 isolated from buffaloes with Oedematous Skin Disease "biotype 2". All isolates were identified by standard microbiological techniques and by polymerase chain reaction targeting, 16S rRNA and phospholipase D genes. Synergisti
Brazilian Journal of Microbiology. Publicado em: 2012-06
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31. A conjugate of an anti-midkine single-chain variable fragment to doxorubicin inhibits tumor growth
Doxorubicin (DOX) was conjugated to a single-chain variable fragment (scFv) against human midkine (MK), and the conjugate (scFv-DOX) was used to target the chemotherapeutic agent to a mouse solid tumor model in which the tumor cells expressed high levels of human MK. The His-tagged recombinant scFv was expressed in bacteria, purified by metal affinity chroma
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-03
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32. Profile of total IgG, IgG1, IgG2, IgG3 and IgG4 levels in sera of patients with paracoccidioidomycosis: treatment follow-up using Mexo and rPb27 as antigens in an ELISA
The levels of total of IgG, IgG1, IgG2, IgG3 and IgG4 were evaluated in 54 patients with chronic paracoccidioidomycosis (PCM) before, during and after treatment using an enzyme-linked immunosorbent assay with Mexo and recombinant Pb27 (rPb27) as the antigens. Mexo was effective in distinguishing PCM patients from individuals in the negative control group (NC
Mem. Inst. Oswaldo Cruz. Publicado em: 2012-02
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33. Serological evidence of hantavirus infection in rural and urban regions in the state of Amazonas, Brazil
Hantavirus disease is caused by the hantavirus, which is an RNA virus belonging to the family Bunyaviridae. Hantavirus disease is an anthropozoonotic infection transmitted through the inhalation of aerosols from the excreta of hantavirus-infected rodents. In the county of Itacoatiara in the state of Amazonas (AM), Brazil, the first human cases of hantavirus
Memórias do Instituto Oswaldo Cruz. Publicado em: 2012-02
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34. Detecção de DNA de herpesvírus em gânglios trigêmeos de bovinos e avaliação de um herpesvírus bovino tipo 5 recombinante como antígeno vacinal / Detection of herpesviruses dna in trigeminal ganglia of bovine and evaluation of a recombinant bovine herpesvirus type 5 (bohv-5) recombinant as inactivated vaccinal antigen
Os herpesvírus bovinos tipos 1 (BoHV-1), 2 (BoHV-2), 4 (BoHV-4), 5 (BoHV-5) e o herpesvírus ovino tipo 2 (OvHV-2) apresentam como característica comum a indução de infecções latentes em seus hospedeiros. Estes agentes estão associados a diferentes enfermidades em bovinos, embora na maioria dos animais infectados a infecção primária ocorra com pouc
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
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35. Antibody response against recombinant proteins based on Plasmodium vivax merozoite antigens in individuals from a rural community of the Brazilian Amazonia / Resposta de anticorpos contra proteínas recombinantes baseadas em antígenos de merozoítos de Plasmodium vivax em indivíduos de uma comunidade rural da Amazônia brasileira
In recent years we studied various aspects of the naturally acquired immune response in individuals from different endemic areas of the Amazon region exposed to malaria. For this purpose we used recombinant proteins based on P. vivax blood stage antigens considered candidates for a vaccine against vivax malaria. In the present study, we focused on 396 indivi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/05/2011
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36. Análise cinética da resposta imune humoral contra a proteína recombinante SAG2A em pacientes com Toxoplasmose aguda
Proteínas recombinantes de Toxoplasma gondii têm sido utilizadas em diversos modelos experimentais, assim como para o diagnóstico sorológico da infecção humana por este parasito, principalmente com o intuito de diferenciar as fases aguda e crônica da toxoplasmose. Neste estudo, foi avaliada a cinética dos anticorpos IgM, IgA ,IgG e subclasses (IgG1 e
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/03/2011