Receptors
Mostrando 13-24 de 14291 artigos, teses e dissertações.
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13. Obesity care: more urgent than ever
ABSTRACT Deleterious effects of free fatty acids, FFAs, on insulin sensitivity are observed in vivo studies in humans. Mechanisms include impaired insulin signaling, oxidative stress, inflammation, and mitochondrial dysfunction, but the effects on insulin secretion are less well known. Our aim was to review the relationship of increased FFAs with insulin res
Arch. Endocrinol. Metab.. Publicado em: 2021-02
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14. Effect of free fatty acids on insulin secretion, insulin sensitivity and incretin effect – a narrative review
ABSTRACT Deleterious effects of free fatty acids, FFAs, on insulin sensitivity are observed in vivo studies in humans. Mechanisms include impaired insulin signaling, oxidative stress, inflammation, and mitochondrial dysfunction, but the effects on insulin secretion are less well known. Our aim was to review the relationship of increased FFAs with insulin res
Arch. Endocrinol. Metab.. Publicado em: 2021-02
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15. Primary hypothyroidism with exuberant dermatological manifestations,
Abstract Thyroid hormone has effects on the skin. Patients with hypothyroidism have changes such as dry, scaly and rough skin. Increase carotene in the dermis becomes a yellowish tone to the skin of the patient with hypothyroidism. There is an increase in capillary cycle (anagen phase) and nail growth and a reduction in eccrine gland secretion. It is a case
An. Bras. Dermatol.. Publicado em: 2020-12
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16. A Calix[4]arene-Functionalized Perylene Imide and Its Luminescence Properties
In this study, new perylene-derived molecules were synthesized as perylene-3,4,9,10-tetracarboxylic acid monoanhydride monopotassium carboxylate 1; N-(3-propanol)perylene-3,4,9,10-tetracarboxylic-3,4-(monoimide)anhydride-9,10-acid potassium carboxylate 2; 5,11,17,23-tetra(tert-butyl)-25,27-bis(3’-bromopropoxy)-26,28-(dihydroxy)calix[4]arene 3; 5,11,17,23-t
J. Braz. Chem. Soc.. Publicado em: 2020-11
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17. Association between vitamin D and cardioprotection in adult patients
SUMMARY OBJECTIVE: To conduct a review of articles which have evaluated the relationship between vitamin D and cardioprotection in adult. METHODS: A literature search was performed in the Pubmed and Scielo databases. The results were extracted from primary and secondary sources and will be presented in the form of a bibliographic review. RESULTS: Twenty-t
Rev. Assoc. Med. Bras.. Publicado em: 2020-10
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18. O Paradoxo da Obesidade na Insuficiência Cardíaca Depende da Aptidão Cardiorrespiratória?
ABSTRACT Objectives Graves’ disease (GD) is an autoimmune disease causing the overproduction of the thyroid hormone from thyroid gland. This disease is mainly the result of the production of antibodies against TSH receptors. Cytokines play an important role in orchestrating the pathophysiology in autoimmune thyroid disease. The regulatory role of IL-12 o
Arq. Bras. Cardiol.. Publicado em: 2020-10
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19. Potential Role of Hematological Parameters in Patients with Acute Myocardial Infarction: viewpoint
ABSTRACT Objectives Graves’ disease (GD) is an autoimmune disease causing the overproduction of the thyroid hormone from thyroid gland. This disease is mainly the result of the production of antibodies against TSH receptors. Cytokines play an important role in orchestrating the pathophysiology in autoimmune thyroid disease. The regulatory role of IL-12 o
Int. J. Cardiovasc. Sci.. Publicado em: 2020-10
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20. Decreased serum levels of IL-27and IL-35 in patients with Graves disease
ABSTRACT Objectives Graves’ disease (GD) is an autoimmune disease causing the overproduction of the thyroid hormone from thyroid gland. This disease is mainly the result of the production of antibodies against TSH receptors. Cytokines play an important role in orchestrating the pathophysiology in autoimmune thyroid disease. The regulatory role of IL-12 o
Arch. Endocrinol. Metab.. Publicado em: 2020-10
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21. Corticotropin-releasing factor receptor signaling and modulation: implications for stress response and resilience
Abstract Introduction In addition to their role in regulation of the hypothalamic-pituitary-adrenal-axis, corticotropin-releasing factor (CRF) and its related peptides, the urocortins, are important mediators of physiological and pathophysiological processes of the central nervous, cardiovascular, gastrointestinal, immune, endocrine, reproductive, and skin
Trends Psychiatry Psychother.. Publicado em: 2020-06
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22. Intravascular histiocytosis: case report of a rare disease probably associated with silicone breast implant,
Abstract Intravascular histiocytosis is a rare condition characterized by the aggregate of histiocytes within dilated dermal vessels. The diagnosis is mainly histophatological and immunohistochemical. We describe a case of a 55 year-old female patient presenting erythematous/purple patches on the breasts, back and limbs. She previously presented ductal carci
An. Bras. Dermatol.. Publicado em: 2020-06
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23. Melatonin decreases cocaine-induced locomotor activity in pinealectomized rats
Objective: Several studies have shown that the time of day regulates the reinforcing effects of cocaine. Additionally, melatonin and its MT1 and MT2 receptors have been found to participate in modulation of the reinforcing effects of such addictive drugs as cocaine. Loss of the diurnal variation in cocaine-induced locomotor sensitization and cocaine-induced
Braz. J. Psychiatry. Publicado em: 2020-06
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24. Application of a New Validated HPLC-PDA Method for Simultaneous Determination of Curcumin and Melatonin in Hyaluronic Acid-Coated Nanoemulsions
In this study, a high-performance liquid chromatography with photodiode array detector (HPLC-PDA) method was developed and validated to simultaneously determine curcumin (CUR) and melatonin (MEL) in hyaluronic acid-coated nanoemulsions, a novel targetable delivery system to CD44 receptors overexpressed in many types of tumors. Chromatographic analyses were p
J. Braz. Chem. Soc.. Publicado em: 2020-03