Receptor 1
Mostrando 13-24 de 16807 artigos, teses e dissertações.
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13. Quais são as manifestações orais decorrentes diretamente da infecção por SARS-CoV-2?
Das infecções da mucosa oral decorrentes do Sars-Cov-2, podemos citar úlceras, bolhas, gengivite necrosante, coinfecções oportunistas e alterações das glândulas salivares. Placas brancas e eritematosas e disfunção gustativa foram as mais relatadas manifestações clínicas orais em pacientes com Covid-19. Em geral, as lesões aparecem concomitan
Núcleo de Telessaúde Amazonas. Publicado em: 12/06/2023
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14. Como proceder em casos de uso crônico de benzodiazepínicos em pacientes com histórico de insônia?
Inicialmente é preciso definir o padrão de sono (pregresso e atual) do paciente, a fim de diagnosticar seu quadro clínico e as possíveis causas para o relato de insônia. Avaliar a presença de comorbidades (incluindo a depressão) e o uso de outras medicações que possam interferir no ciclo sono-vigília.
O uso crônico de benzodiazepínicos,
Núcleo de Telessaúde Sergipe. Publicado em: 12/06/2023
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15. A fitoterapia pode ser uma opção terapêutica para obesidade?
O tratamento da obesidade é complexo e multidisciplinar, sendo que pode incluir intervenções não medicamentosas e medicamentosas. A fitoterapia, entre outros, é um tratamento não medicamentoso que pode estar associado a outros tratamentos da obesidade.¹ Há estudos que avaliam algumas plantas medicinais para o tratamento da obesidade, dentre as q
Núcleo de Telessaúde Santa Catarina. Publicado em: 12/06/2023
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16. Effects of antidiabetics and exercise therapy on suppressors of cytokine signaling-1, suppressors of cytokine signaling-3, and insulin receptor substrate-1 molecules in diabetes and obesity
SUMMARY OBJECTIVE: Pathological destruction of insulin signaling molecules such as insulin receptor substrate, especially due to the increase in suppressors of cytokine signaling molecules, has been demonstrated in experimental diabetes. The contribution of suppressors of cytokine signaling proteins to the development of insulin resistance and the effects o
Revista da Associação Médica Brasileira. Publicado em: 2023
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17. Effects of enhancer of zeste homolog 2 and mucin 1 expressions on treatment response in breast cancer
SUMMARY OBJECTIVE: Breast cancer is the most common malignancy in women. In the treatment of these patients, pathological complete response is defined as the absence of invasive cancer in breast or lymph node tissue after the completion of neoadjuvant chemotherapy. In this study, we aimed to investigate the relationship of enhancer of zeste homolog 2 and mu
Revista da Associação Médica Brasileira. Publicado em: 2023
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18. Molecular mechanism of benign biliary stricture inhibition by rosiglitazone-activated peroxisome proliferator-activated receptor gamma
SUMMARY OBJECTIVE: The aim of this study was to investigate whether rosiglitazone-activated peroxisome proliferator-activated receptor gamma can inhibit the occurrence of benign biliary stricture and further elucidate the relevant molecular signaling mechanism. METHODS: The primary cultured rat biliary fibroblasts following experiments were performed using
Revista da Associação Médica Brasileira. Publicado em: 2022
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19. The effect of alpha-2A adrenergic receptor (ADRA2A) genetic polymorphisms on the depth of sedation of dexmedetomidine: a genetic observational pilot study
Abstract Background: The genetic polymorphisms of the alpha-2A adrenergic receptor (ADRA2A), which plays a significant role in sedation, anxiety relief, and antinociception, particularly in dexmedetomidine, may differ in the degree of sedation. This study aimed to investigate the effect of the genetic polymorphisms of ADRA2A (rs11195418, rs1800544, rs248451
Brazilian Journal of Anesthesiology. Publicado em: 2022
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20. Ayahuasca and its interaction with the sigma-1 receptor: a potential treatment for COVID-19
Brazilian Journal of Psychiatry. Publicado em: 2022
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21. Cannabinoid receptor gene polymorphisms and cognitive performance in patients with schizophrenia and controls
Objective: To test the hypothesis that genetic variations of cannabinoid receptors contribute to the pathophysiology of cognitive deficits in schizophrenia. Methods: In this genetic association case-control study, cannabinoid receptor polymorphisms CNR1 rs12720071 and CNR2 rs2229579 were tested for association with neurocognitive performance in 69 patients
Brazilian Journal of Psychiatry. Publicado em: 2022
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22. Photosensitive rash induced by nivolumab
Abstract The therapeutic approach to metastatic melanoma has revolutionized the clinical course of this disease. Since 2011, different immunotherapeutic drugs have been approved. Nivolumab is a humanized immunoglobulin IgG4 monoclonal antibody that binds to the PD-1 receptor, blocking its interaction with his ligand PD-L1. The authors present a new case of p
Anais Brasileiros de Dermatologia. Publicado em: 2022
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23. Bloqueadores do Receptor de Angiotensina Avaliados por Medida de Consultório e Residencial da Pressão Arterial. Estudo TeleMRPA
Resumo Fundamento O tratamento adequado e a obtenção das metas na hipertensão arterial são importantes na redução dos desfechos cardiovasculares. Objetivos Descrever os bloqueadores do receptor de angiotensina (BRA) em monoterapia ou combinação dupla e a taxa de controle da hipertensão arterial. Métodos Estudo transversal que avaliou paciente
Arquivos Brasileiros de Cardiologia. Publicado em: 2022
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24. Vitamin D metabolism and extraskeletal outcomes: an update
ABSTRACT Vitamin D deficiency is a general health problem affecting individuals at all stages of life and on different continents. The musculoskeletal effects of vitamin D are well known. Its deficiency causes rickets, osteomalacia, and secondary hyperparathyroidism and increases the risk of fractures. Clinical and experimental evidence suggests that vitamin
Archives of Endocrinology and Metabolism. Publicado em: 2022