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Mostrando 1-12 de 398 artigos, teses e dissertações.
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1. Expression Level and Significance of Tim-3 in CD4+ T Lymphocytes in Peripheral Blood of Patients with Coronary Heart Disease
Abstract Objective: To investigate the expression level and significance of T cell immunoglobulin and mucin-domain containing molecules-3 (Tim-3) and interleukin-7 (IL-7) in CD4+ T lymphocytes in peripheral blood of patients with coronary heart disease (CHD). Methods: 75 patients with CHD treated at our hospital were selected and classified as mild group (
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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2. Interplay of Oxidative Stress and Nitric Oxide Synthase Gene Expression on Cardiovascular Responses in Preeclampsia
Resumo Objetivo Avaliar a influência do estresse oxidativo na expressão genética das óxido nítrico sintases (nitric oxide synthases, NOS, em inglês; NOS 3 e NOS 2) e, consequentemente, nas respostas cardiovasculares na pré-eclâmpsia. Métodos Este foi um estudo caso-controle no qual pacientes com pré-eclâmpsia (grupo PE) e controles comgravidez n
Revista Brasileira de Ginecologia e Obstetrícia. Publicado em: 2022
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3. A new biomarker in severe pneumonia associated with coronavirus disease 2019: hypoalbuminemia. A prospective study
ABSTRACT BACKGROUND: Effective triage and early detection are very important for controlling and treating coronavirus disease 2019 (COVID-19). Thus, the relationships between hypoalbuminemia and other acute-phase reactants in such cases need to be evaluated. OBJECTIVES: To investigate the importance of albumin levels in cases of severe pneumonia due to COV
Sao Paulo Medical Journal. Publicado em: 2022
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4. Fast, cheap and feasible: Implementation of pediatric telemedicine in a public hospital during the Covid-19 pandemic
Abstract Objective: In Brazil, telemedicine was allowed as an exception during the coronavirus disease (COVID-19) pandemic. Despite its recognized value and availability, telemedicine is not universally used, suggesting that some barriers prevent its adoption and acceptance within the community. This study aims to describe the implementation of a low-cost t
Jornal de Pediatria. Publicado em: 2022
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5. Long non-coding RNA HOTAIR induces the PI3K/AKT/mTOR signaling pathway in breast cancer cells
SUMMARY OBJECTIVE: The phosphoinositide 3-kinase/protein kinase AKT/mammalian target of rapamycin signaling pathway is essential for proper cellular metabolism and cell growth. However, aberrant activation of this pathway has been linked to the progression and metastasis of breast cancer. Recently, the role of long non-coding RNAs in interfering with the ce
Revista da Associação Médica Brasileira. Publicado em: 2022
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6. Effect of crosstalk between Th17 and Th9 cells on the activation of dermal vascular smooth muscle cells in systemic scleroderma and regulation of tanshinone IIA
Abstract Background: To evaluate the effect of T-helper 17 (Th17) cells and Th9 cells on the activation of dermal vascular smooth muscle cells (DVSMCs) in systemic scleroderma (SSc) and regulation of tanshinone IIA. Methods: The expression of interleukin 17 receptor (IL-17R) and interleukin 9 receptor (IL-9R) in the skin of SSc patients was assessed by imm
Anais Brasileiros de Dermatologia. Publicado em: 2022
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7. COVID-19 and adult acute lymphoblastic leukemia: Presentation and management
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common malignancy in children characterized by the overproduction and accumulation of immature lymphoid cells in the bone marrow and peripheral blood. The BMI-1 is an important component of the Polycomb Repressive Complex-1 (PRC1). It is an important molecule for the self-renewal of hematopo
Hematol., Transfus. Cell Ther.. Publicado em: 2021-06
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8. Utility of BMI-1 and NANOG expression levels in survival prediction of pediatric acute lymphoblastic leukemia
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common malignancy in children characterized by the overproduction and accumulation of immature lymphoid cells in the bone marrow and peripheral blood. The BMI-1 is an important component of the Polycomb Repressive Complex-1 (PRC1). It is an important molecule for the self-renewal of hematopo
Hematol., Transfus. Cell Ther.. Publicado em: 2021-06
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9. Laboratory diagnosis of COVID-19
Abstract Objectives: This was a non-systematic review of the literature on the laboratory diagnosis of COVID-19. Data sources: Searches in PubMed and Google Scholar for articles made available in 2020, using the terms “diagnosis” OR “diagnostic” OR “diagnostic tests” OR “tests” AND “COVID-19” OR “SARS-CoV-2” in the title. Summary o
J. Pediatr. (Rio J.). Publicado em: 2021-02
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10. Reverse-transcriptase polymerase chain reaction versus chest computed tomography for detecting early symptoms of COVID-19. A diagnostic accuracy systematic review and meta-analysis
ABSTRACT BACKGROUND: A positive real-time reverse-transcriptase polymerase chain reaction (RT-PCR) for SARS CoV-2, from nasopharyngeal swabs, is the current gold standard diagnostic test for this virus and has sensitivity of 60-70%. Some studies have demonstrated a significant number of false-negative RT-PCR tests while displaying significant tomographic f
Sao Paulo Med. J.. Publicado em: 2020-10
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11. Saliva is a reliable, non-invasive specimen for SARS-CoV-2 detection
Abstract Background Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the cause of Coronavirus Disease 2019 (COVID-19). Although Real Time Reverse Transcription Polymerase Chain Reaction (qRT-PCR) of respiratory specimens is the gold standard test for detection of SARS-CoV-2 infection, collecting nasopharyngeal swabs causes discomfort to patie
Braz J Infect Dis. Publicado em: 2020-10
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12. Epidemiologia do esgoto como estratégia para monitoramento comunitário, mapeamento de focos emergentes e elaboração de sistemas de alerta rápido para COVID-19
The ability to monitor the spread of diseases is essential for prevention, intervention and control practices. In this context, wastewater-based epidemiology (WBE) has been applied to empirically evaluate the exposure of populations to chemical substances and pathogens of emerging concern in near real time. During the current COVID-19 pandemic, WBE remains a
Quím. Nova. Publicado em: 2020-04