Rational Drug Use
Mostrando 25-36 de 49 artigos, teses e dissertações.
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25. The polypharmacy in elderly in São Paulo SABE Study Health, Well-being and aging. / A polifarmácia em idosos no município de São Paulo - Estudo SABE - Saúde, Bem-estar e Envelhecimento
Introduction: The continuous growth of the elderly population increases the need for further health resources; amongst them is the use of drugs.Object: Study the risks Polypharmacy in the population of elderly people within the city of São Paulo, Brasil. Method: This study is part of the SABE project Health, Well-being and aging. This survey is car
Publicado em: 2007
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26. Generic drugs and its social importance the municipal policlinic from Campinas-São José/SC case / O uso dos medicamentos genéricos e sua relevância social : o caso da Policlínica Municipal de Campinas - São José
Como forma de contribuir para a avaliação da política nacional de medicamentos genéricos e sua relevância social, este trabalho investigou, mediante estudo de caso em uma unidade pública de saúde, o conhecimento que têm prescritores, dispensadores e usuários relativamente aos medicamentos genéricos e a confiança que neles depositam. Para situar hi
Publicado em: 2007
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27. Economic evaluation of Pharmaceutical Care activity impact in health assistance: methodological aspects. / Avaliação econômica do impacto da atividade de atenção farmacêutica na assistência à saúde: aspectos metodológicos
A atenção farmacêutica (ATENFAR) é uma nova prática clínica, inerente ao profissional farmacêutico, que tem como principais objetivos a prevenção de doenças, a promoção e a recuperação da saúde de usuários de serviços sanitários, através do fomento ao uso racional de medicamentos. Vários estudos realizados no Brasil e no exterior mostram
Publicado em: 2007
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28. Estudo retrospectivo sobre a terapêutica anti-hipertensiva de uma unidade do Programa de Saúde da Família / Retrospective study of antihypertensive therapeutic drug pratices of a unit of the Family Health Care Program
Introduction: Cardiovascular diseases are the currently leading cause of mortality in Brazil and also the set of illnesses that is the largest expense in health system. Amongst them, there is one that deserves special attention for being tied the diverse origins and to be factor of aggravation for other pathologies: hypertension. The actual model of care is
Publicado em: 2006
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29. The use of biodiversity as source of new chemical entities against defined molecular targets for treatment of malaria, tuberculosis, and T-cell mediated diseases: a review
The modern approach to the development of new chemical entities against complex diseases, especially the neglected endemic diseases such as tuberculosis and malaria, is based on the use of defined molecular targets. Among the advantages, this approach allows (i) the search and identification of lead compounds with defined molecular mechanisms against a defin
Memórias do Instituto Oswaldo Cruz. Publicado em: 2005-10
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30. Farmacoeconomía: eficiencia y uso racional de los medicamentos
This paper is a discussion about pharmacoeconomics contributes to increase the efficiency levels in the field of drug use. By this discipline's work guidelines, different pharmacoeconomic applications will be able to be performed, both in the field of sanitary-services offering and in the process of obtaining new drugs by the pharmaceutical industry. As a re
Revista Brasileira de Ciências Farmacêuticas. Publicado em: 2004-12
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31. Operacionalizando conceitos em farmacoepidemiologia : estudos de utilização de medicamentos e de farmacovigilancia
BACKGROUND: In all phases of the process of development of a new medicine the drug safety and the profile of adverse drug reactions it is always object of a lot of attention. Though, even with all the methodological concerns, when a drug goes to the postmarketing phase, a small number of patients were exposed indeed to the new drug. Pharmacoepidemiology uses
Publicado em: 2004
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32. La política farmacéutica nacional en Colombia y la reforma de la seguridad social: acceso y uso racional de medicamentos
Based on the new social security system in Colombia (1993), which establishes equity and mandatory care as the basis for public health care provision, the authors analyze whether the formulation and implementation of pharmaceutical policy promote accessibility, availability, and rational use of medicines, thereby contributing to equity in health. Two approac
Cadernos de Saúde Pública. Publicado em: 2002-08
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33. Prescrição de medicamentos em serviço de emergencia psiquiatrica : um estudo farmacoepidemiologico
Background. Psychotherapeutic drugs constitute the main therapeutic approach in psychiatric emergency services (PES). Few studies have evaluated the prescription patterns of drugs used in these settings. Objective. This study describes drug use as stat medication at a Psychiatric Emergency Service. Methods. A descriptive retrospective study evaluated the med
Publicado em: 2002
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34. Centros de informação sobre medicamentos no Brasil : passado, presente e perspectivas do Sistema Brasileiro de Informação sobre Medicamentos
Introduction. After discussion on different elements that justify the existence of DICs, definitions of drug information and drug information centers were given and related to the usual activities of the centers, having the passive information as their main activity, the pharmacist, who is a specialist in drug information is the professional who has the most
Publicado em: 1999
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35. Rational Dose Selection for a Nonnucleoside Reverse Transcriptase Inhibitor through Use of Population Pharmacokinetic Modeling and Monte Carlo Simulation
In order to choose a rational dose for GW 420867X, we first set a goal of therapy. We hypothesized that, for optimal antiretroviral activity, the trough free drug concentration should remain above the 90% effective concentration (EC90) of human immunodeficiency virus type 1. We performed population pharmacokinetic analysis on three different doses of GW 4208
American Society for Microbiology.
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36. Rational screening of oligonucleotide combinatorial libraries for drug discovery.
Combinatorial strategies offer the potential to generate and screen extremely large numbers of compounds and to identify individual molecules with a desired binding specificity or pharmacological activity. We describe a combinatorial strategy for oligonucleotides in which the library is generated and screened without using enzymes. Freedom from enzymes enabl