Proteomics
Mostrando 13-24 de 399 artigos, teses e dissertações.
-
13. Radiation-induced Changes in the Electrophoretic Profile of Serum Albumin
ABSTRACT Albumin protein profiles were investigated in electrophoresis system in relation to the whole body exposition to the radiation. Two groups of rats Wistar were set up as the control (CG) and the irradiated one (IG). The IG was exposed to Co-60 at a dose of 5 Gy. After a 72-hour exposition, 300 μL of blood was collected in the inferior vena cava, ren
Braz. arch. biol. technol.. Publicado em: 08/01/2018
-
14. It is time for top-down venomics
Abstract The protein composition of animal venoms is usually determined by peptide-centric proteomics approaches (bottom-up proteomics). However, this technique cannot, in most cases, distinguish among toxin proteoforms, herein called toxiforms, because of the protein inference problem. Top-down proteomics (TDP) analyzes intact proteins without digestion and
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 21/11/2017
-
15. Strategies in ‘snake venomics’ aiming at an integrative view of compositional, functional, and immunological characteristics of venoms
Abstract This work offers a general overview on the evolving strategies for the proteomic analysis of snake venoms, and discusses how these may be combined through diverse experimental approaches with the goal of achieving a more comprehensive knowledge on the compositional, toxic, and immunological characteristics of venoms. Some recent developments in this
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 06/07/2017
-
16. Protein-species quantitative venomics: looking through a crystal ball
Abstract In this paper we discuss recent significant developments in the field of venom research, specifically the emergence of top-down proteomic applications that allow achieving compositional resolution at the level of the protein species present in the venom, and the absolute quantification of the venom proteins (the term “protein species” is used he
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 06/07/2017
-
17. Oxidative Stress Parameters, Related Trace Elements Levels and Proteomics in Soybean Seeds in Order to Get a Better Assessment of Their Quality
Antioxidant systems, Fe, Cu, Zn, Mn and Ni levels and proteomics in soybean seeds of different performance in field were assessed. These results were correlated with the in vitro tests required by regulatory organisms, and the actual behavior in field. Basal superoxide content, superoxide dismutase (SOD) activity (20-80 U mg-1 protein) and 2,2-diphenyl-1-pic
J. Braz. Chem. Soc.. Publicado em: 2015-10
-
18. Proteomics analysis of tissue samples from patients with squamous cell carcinoma of the penis and positive to human papillomavirus
ABSTRACTPurpose:The aim of this study was to identify possible protein biomarkers and/or candidates for therapeutic targets in tissues of patients with SCCP, infected by HPV, applying one dimensional electrophoresis (1DE), followed by direct mass spectrometry (MS) analysis.Materials and Methods:Tissues from 10 HPV positive patients with SCCP and from 10 pati
Int. braz j urol.. Publicado em: 2015-08
-
19. Biomarkers in mood disorders research: developing new and improved therapeutics
Background Recently, surrogate neurobiological biomarkers that correlate with target engagement and therapeutic response have been developed and tested in early phase studies of mood disorders. Objective The identification of biomarkers could help develop personalized psychiatric treatments that may impact public health. Methods These biomarkers, which are
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2014
-
20. Analysis of the chemical components of hydatid fluid from Echinococcus granulosus
Introduction The aim of this study was to explore the environment of Echinococcus granulosus (E. granulosus) protoscolices and their relationship with their host. Methods Proteins from the hydatid-cyst fluid (HCF) from E. granulosus were identified by proteomics. An inductively coupled plasma atomic emission spectrometer (ICP-AES) was used to determine
Rev. Soc. Bras. Med. Trop.. Publicado em: 21/10/2013
-
21. Urine screening by Seldi-Tof, followed by biomarker identification, in a Brazilian cohort of patients with Renal Cell Carcinoma (RCC)
Purpose To screen proteins/peptides in urine of Renal Cell Carcinoma (RCC) patients by SELDI-TOF (Surface Enhanced Laser Desorption Ionization - Time of Flight) in search of possible biomarkers. Material and Methods Sixty-one urines samples from Clear Cell RCC and Papillary RCC were compared to 29 samples of control urine on CM10 chip. Mass analysis was p
Int. braz j urol.. Publicado em: 2013-04
-
22. Avaliação do metabolismo primário da região cambial e casca de Eucalyptus grandis / Evaluation of the primary metabolism of Eucalyptus grandis cambial region and bark
Eucalyptus genus is the most widely planted hardwood crop in the world because of its superior growth, broad adaptability and multipurpose wood properties. In today\ s \"new carbon economy\", eucalypts are receiving attention as fast-growing, short-rotation, renewable biomass crop for energy production. In spite of its economical importance, little informati
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/11/2012
-
23. Estudo comparativo do perfil metabolômico e proteômico de uvas (Vitis vinifera) durante o processo de maturação utilizando ferramentas bioanalíticas / Comparative study of metabolomic and proteomic profiles of grapes (Vitis vinifera) during ripening using bioanalytical tools
A análise da composição química das uvas é de grande importância para avaliar a data da colheita e a produção de vinhos de qualidade. O estudo do metabolismo das uvas é essencial para definirem-se em quais etapas os metabólitos são produzidos, assim como as proteínas e genes que regulam esses processos. Açúcares, polifenóis e ácidos orgânico
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/07/2012
-
24. Efeito do fluoreto no osso de camundongos com diferentes susceptibilidades genéticas à fluorose: uma análise proteômica / Effect of fluoride on bone of mice with different genetic susceptibilities to fluorosis: a proteomic analysis
Genetic factors have been shown to influence bone and enamel responses to fluoride (F), but the molecular mechanisms involved remain unclear. In this study, a label-free proteomics approach was employed to identify and evaluate changes in bone protein expression of two mouse strains with different susceptibilities to fluorosis (A/J a susceptible strain, 129P
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/06/2012