Proteins Biological Models
Mostrando 1-12 de 65 artigos, teses e dissertações.
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1. LIPIDS AS COMPETITIVE INHIBITORS OF SUBTILISIN CARLSBERG IN THE ENZYMATIC HYDROLYSIS OF PROTEINS IN RED TILAPIA (Oreochromis sp.) VISCERA: INSIGHTS FROM KINETIC MODELS AND A MOLECULAR DOCKING STUDY
Abstract Protein hydrolysis can improve food’s nutritional, techno-functional and biological properties, which can increase the possibilities of application in industry. The objective of this research article was to study the effect of lipids on the enzymatic kinetics of red tilapia viscera (RTV) hydrolysis with subtilisin Carlsberg. The RTV were hydrolyze
Braz. J. Chem. Eng.. Publicado em: 30/09/2019
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2. Phyto- and Bio-Chemical evaluation of Diospyros kaki L. cultivated in Egypt and its biological activities
Resumo Diospyros kaki L. ou Costata é a principal variedade de caqui progressivamente consumida no mercado e exportação egípcia. O objetivo deste estudo foi investigar os efeitos bioprotetores do extrato alcoólico de frutos e folhas de D. kaki utilizando modelos de ratos “in vivo”. Extratos de éter de petróleo provenientes de frutos e folhas foram
Braz. J. Biol.. Publicado em: 05/08/2019
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3. Transduction motif analysis of gastric cancer based on a human signaling network
To investigate signal regulation models of gastric cancer, databases and literature were used to construct the signaling network in humans. Topological characteristics of the network were analyzed by CytoScape. After marking gastric cancer-related genes extracted from the CancerResource, GeneRIF, and COSMIC databases, the FANMOD software was used for the min
Braz J Med Biol Res. Publicado em: 04/04/2014
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4. Identificação de alvos protéicos com potencial diagnóstico e prognóstico em doença arterial coronária / Identification of protein targets with potential diagnostic and prognostic in coronary artery disease
Worldwide, millions of patients are treated in emergencies because they had acute-onset chest pain, but only a portion is due to coronary syndrome. In situations like this is extremely important to distinguish when the chest pain is due to myocardial ischemia, as this is high risk and initiation of treatment should be immediate. New biomarkers are needed to
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/06/2012
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5. Characterization of the adhesion genes in biofilm formation and pathogenicity of Xytella fastidiosa and differential expression of proteins / Caracterização dos genes de adesão na formação do biofilme e na patogênicidade de Xylella fastidiosa e expressão diferencial de proteínas
Xylella fastidiosa é o agente causal da clorose variegada dos citros (CVC), da doença de Pierce em videiras e doenças em muitas outras culturas. Com o seqüenciamento completo do genoma de várias linhagens deste organismo, a função de cada gene , principalmente os ligados à virulência ainda estão pouco caracterizados. A fixação da X. fastidiosa no
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/02/2012
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6. Localização genômica e subcelular dos membros da família de fosfatidilinositol quinases em Trypanosoma cruzi / Genomic and subcellular localization of the members of phosphatidylinositol kinase family in Trypanosoma cruzi
The identification of signaling molecules and the elucidation of signal transduction processes of Trypanosoma cruzi are required for understanding the host-parasite interaction and physiological processes of the parasite. However, little is yet known about signal transduction and signaling pathways that occur in the parasite, since most efforts focused on si
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/07/2011
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7. Estudo da expressão da miostatina em modelos murinos para doenças neuromusculares. / Myostatin expression in mouse models of neuromuscular diseases.
A proteína miostatina, é um regulador negativo do crescimento muscular e a modulação de sua expressão pode consistir em tratamento para distrofias musculares. Nós estudamos expressão endógena da miostatina no músculos gastrocnêmio e diafragma de 4 modelos murinos de degeneração muscular: os camundongos Dmdmdx, SJL/J, Largemyd e Lama2dy-2J/J. Obse
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/03/2011
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8. Modelos para a produção de eritropoietina recombinante humana in vivo e in vitro com vetores plasmideais em ovinos / Models for the production of human recombinant erythropoietin in vivo and in vitro with plasmidial vectors in ovine
Some post-translational modifications are necessary for the production of biopharmaceutical proteins, such as recombinant human erythropoietin (rhEPO), with a good specific action and a high biological activity. These modifications are obtained only by bioreactors based on eukaryotic cell as mammary cells. Bioreactors, in vivo or in vitro, with this kind of
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/02/2011
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9. Estudos da dinâmica estrutural da proteína ligante de cálcio S100A12 humana e da lisozima T4 / Structural dynamics studies of human calcium binding protein S100A12 and T4 lysozyme
The work presented here was conceived with two main objectives. The first one, more general, involved the implementation of a new methodology for the study of conformational changes in proteins, i.e., its structural dynamics. The technique of Site-directed Spin Labeling combined with Electronic Paramagnetic Resonance (SDSL-EPR) are the pillars of this new me
Publicado em: 2011
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10. SÍNTESE E CARACTERIZAÇÃO DE COMPLEXOS DE COBRE (II) E ZINCO (II) COM DIPEPTÍDEOS DE INTERESSE BIOLÓGICO / SYTHESIS AND CHARACTERIZATION OF COPPER (II) AND ZINC (II) COMPLEXES WITH DIPEPTIDES OF BIOLOGICAL INTEREST
This work describes the synthesis and characterization of copper (II) and zinc (II) complexes, with dipeptides in solid state. The dipeptides involved were: glycyl-glycine, glycyl-valine, methionyl-methionine, methionyl-glycine and cysteinyl-glycine, whose aminoacids take part in some proteins involved in neurodegeneration processes, more specifically in Alz
Publicado em: 2010
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11. New nitric oxide donors based on ruthenium complexes
Nitric oxide (NO) donors produce NO-related activity when applied to biological systems. Among its diverse functions, NO has been implicated in vascular smooth muscle relaxation. Despite the great importance of NO in biological systems, its pharmacological and physiological studies have been limited due to its high reactivity and short half-life. In this rev
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-01
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12. Actin-interacting and flagellar proteins in Leishmania spp.: bioinformatics predictions to functional assignments in phagosome formation
Several motile processes are responsible for the movement of proteins into and within the flagellar membrane, but little is known about the process by which specific proteins (either actin-associated or not) are targeted to protozoan flagellar membranes. Actin is a major cytoskeleton protein, while polymerization and depolymerization of parasite actin and ac
Genetics and Molecular Biology. Publicado em: 2009