Protein Synthesis
Mostrando 1-12 de 15130 artigos, teses e dissertações.
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1. Bioconjugation Between CdTe Quantum Dots and a Cationic Protein: An Analytical Method to Determine Protamine in Drug and Urine Samples
CdTe quantum dots (QD-CdTe) functionalized with mercaptosuccinic acid (MSA) were synthesized in an aqueous medium, varying synthesis time from 0.5 to 4 h. The nanoprobe were characterized by a direct relationship between synthesis time and QD size (2.61-3.04 nm). The QD-CdTe-MSA interacted with protamine (PT), a cationic protein, forming a bioconjugate, thus
J. Braz. Chem. Soc.. Publicado em: 2021-06
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2. A novel mutation in PRKAR1A gene in a patient with Carney complex presenting with pituitary macroadenoma, acromegaly, Cushing's syndrome and recurrent atrial myxoma
SUMMARY Carney complex (CNC) is a rare syndrome of multiple endocrine and non-endocrine tumors. In this paper we present a 23-year-old Iranian woman with CNC who harbored a novel mutation (c.642dupT) in PRKAR1A gene. This patient presented with pituitary macroadenoma, acromegaly, recurrent atrial myxoma, Cushing's syndrome secondary to primary pigmented nodu
Arch. Endocrinol. Metab.. Publicado em: 2021-06
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3. Hereditary angioedema: a disease seldom diagnosed by pediatricians
Abstract Objectives: To describe the hereditary angioedema to improve awareness of this condition and reduce diagnostic delay. Data sources: Relevant articles in the MEDLINE database through PubMed. Data synthesis: Hereditary angioedema is rare and has an autosomal dominant pattern of inheritance. Its onset occurs mainly in childhood, but there is an impo
J. Pediatr. (Rio J.). Publicado em: 2021-04
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4. Human Inborn Errors of Immunity (HIEI): predominantly antibody deficiencies (PADs): if you suspect it, you can detect it
Abstract Objective: This minireview gathers the scientific foundations of the literature on genetic errors in the development of the humoral immune system to help pediatricians suspect these defects. Sources: A systemic search using the PubMed MEDLINE database was performed for all Predominantly Antibody Deficiencies (PADs) described in the 2020 IUIS Exper
J. Pediatr. (Rio J.). Publicado em: 2021-04
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5. Synthesis of ZnO Nanoparticles by the Sol-Gel Protein Route: A Viable and Efficient Method for Photocatalytic Degradation of Methylene Blue and Ibuprofen
The photocatalytic degradation of methylene blue dye and ibuprofen drug was studied in the presence of zinc oxide, synthetized by the protein sol-gel route. The catalyst, calcined at 1000 ºC, presented a tendentious morphology to filaments characteristic of ZnO crystalline, characterized by X-ray diffraction (XRD) and confirmed by the presence of Zn energy
J. Braz. Chem. Soc.. Publicado em: 2020-08
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6. Synthesis, Characterization and in vitro, in vivo and in silico Anti-Inflammatory Studies of the Novel Hybrid Based on Ibuprofen and 3-Hydroxy-Copalic Acid Isolated from Copaiba Oil (Copaifera multijuga)
A novel anti-inflammatory hybrid 3-ibuprofenyl-copalic acid (3-IbuCA) was synthesized from 3-hydroxy-copalic acid isolated from Amazonian copaiba oil (Copaifera multijuga Hayne), and the anti-inflammatory ibuprofen. After full characterization, several assays to verify its anti-inflammatory effects were performed in vitro, in vivo and in silico (molecular do
J. Braz. Chem. Soc.. Publicado em: 2020-07
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7. BMP4 Induces Cardiomyocyte Hypertrophy Through the Activation of ERK 1/2 Signaling Pathway in H9c2 Cells
Abstract Bone morphogenetic protein-4 (BMP4) is a member of the bone morphogenetic protein family which plays an important role in bone formation, inflammation and cardiac hypertrophy. The aim of this study was to investigate the underlying molecular mechanism that BMP4-induced cardiomyocyte hypertrophy. H9c2 cells were used to measure cell surface area and
Braz. arch. biol. technol.. Publicado em: 20/12/2019
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8. Analysis of NH3-N Slow Release systems for fiber digestibility of low-quality forage: in vitro approach
ABSTRACT: Urea is a common non-protein supplement used in ruminant feed; however, excessive consumption may lead to poisoning by NH3. Although the slow release of urea into the rumen has shown to be an essential aspect for ruminant feed, to date only a few studies have addressed this matter. In this study we examined the influence of five different NH3-N slo
Sci. agric. (Piracicaba, Braz.). Publicado em: 20/12/2019
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9. Influence of High Light Intensity and Nitrate Deprivation on Growth and Biochemical Composition of the Marine Microalgae Isochrysis galbana
Abstract Isochrysis galbana is a brown microalgae widely used as a feed for marine organism in aquaculture. The aim of present study is to investigate the growth, biochemical composition, fatty acid profile, photosynthetic parameters and antioxidant activity (radical scavenging activity) of Isochrysis galbana cells cultivated under different levels (sub-opti
Braz. arch. biol. technol.. Publicado em: 20/12/2019
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10. Red clover silage: an alternative for mitigating the impact of nitrogen excretion in ovine production systems
ABSTRACT The objective was to quantify the flow of intestinal nutrients and nitrogen excretion and retention in sheep receiving isoproteic diets. Eight Texel x Lacaune wethers (average body weight = 25±2.5 kg) were fitted with duodenal cannula and housed in metabolic cages. Wethers were assigned to the treatments in a crossover design with two periods of 20
R. Bras. Zootec.. Publicado em: 25/11/2019
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11. Effect of bacterial endotoxin lipopolysaccharide treatment on duck Leydig cells
Abstract This study aimed to investigate the effects of bacterial endotoxin lipopolysaccharide (LPS) on hormone production and gene expression in duck Leydig cells and its underlying mechanisms. Leydig cells were collected from 200-day-old mallard ducks and divided into five treatment groups (0, 50, 100, 200, and 400 ng/mL LPS). After treatment with LPS for
Anim. Reprod.. Publicado em: 25/11/2019
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12. Novel homozygous mutation in a colombian patient with persistent müllerian duct syndrome: expanded phenotype
ABSTRACT The anti-Müllerian hormone triggers the regression of uterus and fallopian tubes in male embryos; if there are problems in the synthesis or action of this protein, Müllerian structures persist in an otherwise phenotypic male. The most frequent clinical presentation of Persistent Mullerian Duct syndrome is cryptorchidism and inguinal hernia. The fe
Int. braz j urol.. Publicado em: 07/11/2019