Protein Structure
Mostrando 13-24 de 12111 artigos, teses e dissertações.
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13. Benzodioxol Group Driving Supramolecular Arrangement of Two Tri-Methoxy Chalcones onto Β-Secretase 1 Enzyme Active Site
Chalcones are compounds with wide interesting biological activities including Alzheimer’s disease. A comparative study was performed between the chalcones (E)-1-(2-aminophenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one and 1-(6-amino-1,3-benzodioxol-5-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one regarding the influence of benzodioxol group on their molecu
J. Braz. Chem. Soc.. Publicado em: 16/09/2019
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14. Protein identification from the parotoid macrogland secretion of Duttaphrynus melanostictus
ABSTRACT Background: Bufonid parotoid macrogland secretion contains several low molecular mass molecules, such as alkaloids and steroids. Nevertheless, its protein content is poorly understood. Herein, we applied a sample preparation methodology that allows the analysis of viscous matrices in order to examine its proteins. Methods: Duttaphrynus melanostic
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 19/08/2019
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15. Galectin 3: an extraordinary multifunctional protein in dermatology. Current knowledge and perspectives
Abstract: Galectin 3 is a unique ~31 kDa protein that recognizes the N-acetyl-lactosamine structure of several glycoconjugates. It mainly occurs in epithelial and myeloid cells, but is also found in a variety of human cell types. In view of the crucial role played by galectin 3 in the regulation of cellular processes of essential importance and in the pathog
An. Bras. Dermatol.. Publicado em: 29/07/2019
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16. Do different arbuscular mycorrhizal fungi affect the formation and stability of soil aggregates?
RESUMO A estrutura é uma das propriedades mais importantes do solo, definida pelo arranjo das partículas e do espaço poroso formando agregados. Dentre os fatores biológicos que influenciam a formação e estabilização dos agregados no solo, destacam-se os fungos micorrízicos arbusculares (FMAs) através das hifas extrarradiculares e produção de glom
Ciênc. agrotec.. Publicado em: 01/07/2019
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17. Scanning Electron Microscopy and Crystallinity of starches granules from cowpea, black and carioca beans in raw and cooked forms
Abstract Beans are a vital food for the population around the world because it contains a relatively high amount of protein, vitamins, fiber, and minerals, being an important vegetable source of iron, particularly when combined with ascorbic acid and cysteine. The starch content in the seed is between 45 and 60%. This paper evaluated the granular structure o
Food Sci. Technol. Publicado em: 27/06/2019
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18. Identification of a Novel TAZ Gene Mutation in a Family With X-Linked Dilated Cardiomyopathy Barth Syndrome
Abstract Mutations in the tafazzin (TAZ) gene on chromosome Xq28 are responsible for the Barth syndrome (BTHS) phenotype resulting in a loss of function in the protein tafazzin involved in the transacylation of cardiolipin, an essential mitochondrial phospholipid. TAZ gene was investigated in the proband in our study, who died of dilated cardiomyopathy at 8
J. inborn errors metab. screen.. Publicado em: 19/06/2019
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19. Milk from different species on physicochemical and microstructural yoghurt properties
RESUMO: O objetivo da presente pesquisa foi avaliar as diferenças nas propriedades químicas e na estrutura física do iogurte produzido com leite de diferentes espécies (ovinos, bovinos e caprinos). Para cada experimento, leite de ovelha cru (S), vaca (C) e cabra (G), foram usados para fabricar 4L de iogurtes (Y) de cada espécie (SY, CY e GY, respectiva
Cienc. Rural. Publicado em: 13/06/2019
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20. Cardiac function and intracellular Ca2+ handling proteins are not impaired by high-saturated-fat diet-induced obesity
Obesity is often associated with changes in cardiac function; however, the mechanisms responsible for functional abnormalities have not yet been fully clarified. Considering the lack of information regarding high-saturated-fat diet-induced obesity, heart function, and the proteins involved in myocardial calcium (Ca2+) handling, the aim of this study was to t
Braz J Med Biol Res. Publicado em: 27/05/2019
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21. Effect of the antifreeze protein on the microstructure of strawberries (Fragaria ananassa Duch)
Resumo O presente trabalho tem o objetivo de elucidar o efeito da proteína anticongelante sobre a microestrutura e as propriedades físico-químicas do morango hidropônico, avaliado quanto a acidez titulável, pH, cor e microscopia ótica, antes do congelamento, in natura (IN) e impregnado com proteína anticongelante (IP), depois do descongelamento sem pr
Braz. J. Food Technol.. Publicado em: 20/05/2019
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22. Moderate-intensity exercise allows enhanced protection against oxidative stress-induced cardiac dysfunction in spontaneously hypertensive rats
The progression of myocardial injury secondary to hypertension is a complex process related to a series of physiological and molecular factors including oxidative stress. This study aimed to investigate whether moderate-intensity exercise (MIE) could improve cardiac function and oxidative stress in spontaneously hypertensive rats (SHRs). Eight-week-old male
Braz J Med Biol Res. Publicado em: 16/05/2019
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23. Systemic injection of an H4 receptor agonist induces a decrease in CREB and pCREB levels in the cerebellar vermis and prefrontal cortex in mice
Studies have shown that an injection with the histamine H4 receptor agonist VUF-8430 modulates emotional memory processes. In the present study, the aim was to verify if intraperitoneal (ip) injection of VUF-8430 (500 ng/kg) in mice affects the synthesis of proteins required for memory consolidation processes by activating the phosphorylation of CREB (pCREB)
Braz J Med Biol Res. Publicado em: 25/04/2019
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24. In silico prediction of the functional and structural consequences of the non-synonymous single nucleotide polymorphism A122V in bovine CXC chemokine receptor type 1
Resumo O presente estudo objetivou avaliar se o polimorfismo causal A122V promove alterações nas propriedades funcionais e estruturais da proteína receptora de quimiocina CXC do tipo 1 (CXCR1) de bovino Bos taurus por análises in silico. Duas sequências de aminoácidos da CXCR1 bovina foram selecionadas a partir do banco de dados UniProtKB/Swiss-Prot:
Braz. J. Biol.. Publicado em: 18/04/2019