Protein Kinase
Mostrando 25-36 de 12172 artigos, teses e dissertações.
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25. Baicalin ameliorates chronic mild stress-induced depression-like behaviors in mice and attenuates inflammatory cytokines and oxidative stress
The natural flavonoid glycoside baicalin (BA) produces a variety of pharmaceutical effects, particularly for psychiatric/neurological disorders. This study evaluated the behavioral and neuroprotective effects of BA in mice subjected to chronic unpredictable mild stress, a model of depression. BA (25 and 50 mg/kg) significantly increased sucrose consumption a
Braz J Med Biol Res. Publicado em: 19/06/2019
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26. Metaphylactic effect of calcium on milk composition and animal health in post-partum dairy cows
Abstract: The aim of this study was to evaluate the effects of subcutaneous calcium administration in post-partum dairy cows with respect to carbohydrate, protein and lipids metabolism, as well as its effects on milk composition. Twenty post-partum dairy cows were randomly divided into two groups (n=10): a control and a treated group with a single dose (150
An. Acad. Bras. Ciênc.. Publicado em: 19/06/2019
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27. Perfil metabólico de vacas Holandês e mestiças Holandês x Jersey no periparto
RESUMO O objetivo do presente trabalho foi determinar e comparar o perfil metabólico de vacas Holandês (H) e mestiças Holandês x Jersey (HxJ) no periparto. Avaliaram-se 24 vacas, sendo 11 vacas Holandês e 13 mestiças Holandês x Jersey. Semanalmente, coletou-se sangue para a determinação das concentrações séricas de glicose, beta-hidroxibutirato (
Arq. Bras. Med. Vet. Zootec.. Publicado em: 14/06/2019
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28. Protective effect of crocetin from Crocus sativus L. on myocardial ischemia-reperfusion injury in rats
Abstract This study investigated the protective effect of crocetin from Crocus sativus L. on myocardial ischemia-reperfusion injury (MIRI) in rats. Sixty SD rats were randomly divided into sham-operated, model, and low-, medium- and high-dose crocetin groups. Later 3 groups were intragastrically administrated with 10, 20 and 40 mg/kg crocetin from Crocus sat
Food Sci. Technol. Publicado em: 06/06/2019
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29. Parâmetros fisiológicos e bioquímicos de equinos em treinamento de três tambores: pós-condicionamento, pós-percurso e pós-descanso
RESUMO Foram avaliados parâmetros fisiológicos e bioquímicos em equinos Quarto de Milha durante treinamento de três tambores, antes do condicionamento (T0), após o condicionamento (T1), após um percurso (T2), após descanso do percurso, por 20 minutos (T3) e após descanso do percurso, por 40 minutos (T4). Os parâmetros físicos avaliados foram: frequ
Arq. Bras. Med. Vet. Zootec.. Publicado em: 06/06/2019
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30. Mechanisms by Which Metabolic Reprogramming in GSD1 Liver Generates a Favorable Tumorigenic Environment
Abstract Glycogen storage disease type 1 (GSD1) is an inherited disorder caused by impaired glucose 6-phosphatase activity. This impairment translates into the inhibition of endogenous glucose production and the subsequent accumulation of cellular glucose 6-phosphate. Excess glucose 6-phosphate enhances glycolysis, increases the production of fatty acids, ur
J. inborn errors metab. screen.. Publicado em: 30/05/2019
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31. Dietary Management of the Ketogenic Glycogen Storage Diseases
Abstract The glycogen storage diseases (GSDs) comprise a group of rare inherited disorders of glycogen metabolism. The hepatic glycogenolytic forms of these disorders are typically associated with hypoglycemia and hepatomegaly. For GSD I, secondary metabolic disturbances include fasting hyperlactatemia, hyperuricemia, and hyperlipidemia. Glycogen storage dis
J. inborn errors metab. screen.. Publicado em: 30/05/2019
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32. PERFIL BIOQUÍMICO SÉRICO DE VACAS DAS RAÇAS NELORE E GIROLANDO CRIADAS NO ESTADO DO MARANHÃO
Resumo O objetivo do trabalho foi avaliar a atividade sérica da aspartato aminotransferase (AST), fosfatase alcalina (ALP), creatina quinase (CK), gamaglutamiltransferase (GGT) e as concentrações séricas de albumina, bilirrubina, cálcio total e ionizado, colesterol, creatinina, fósforo, magnésio, potássio, proteína total, sódio, triglicérides e ur
Ciênc. anim. bras.. Publicado em: 20/05/2019
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33. Overexpression of CDC7 in malignant salivary gland tumors correlates with tumor differentiation
Resumo Introdução: A cell division cycle-7 é uma serina/treonina quinase que tem um papel básico na regulação do ciclo celular e é um potencial marcador prognóstico ou terapêutico em alguns tipos de câncer humano. Objetivos: Este estudo investigou a expressão de cell division cycle-7 em tumores de glândulas salivares benignos e malignos e tamb�
Braz. j. otorhinolaryngol.. Publicado em: 29/04/2019
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34. Skp2 inhibitor SKPin C1 decreased viability and proliferation of multiple myeloma cells and induced apoptosis
Multiple myeloma (MM) is a malignant neoplasm of plasma, and exhibits several harmful effects including osteolytic injuries, hypercalcemia, and immune dysfunction. Many patients with MM succumb to the underlying malignancy. An S-phase kinase-related protein 2 (Skp2) inhibitor, designated SKPin C1, has been developed and confirmed to have an inhibitory effect
Braz J Med Biol Res. Publicado em: 25/04/2019
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35. Comparing the effects of vitamin E tocotrienol-rich fraction supplementation and α-tocopherol supplementation on gene expression in healthy older adults
OBJECTIVES This study aims to compare the differential gene expression resulting from tocotrienol-rich fraction and α-tocopherol supplementation in healthy older adults. METHODS A total of 71 eligible subjects aged 50 to 55 years from Gombak and Kuala Lumpur, Malaysia, were divided into three groups and supplemented with placebo (n=23), α-tocopherol (n
Clinics. Publicado em: 11/03/2019
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36. Gliclazide reduced oxidative stress, inflammation, and bone loss in an experimental periodontal disease model
Abstract Objective The aim of this study was to evaluate the effects of gliclazide on oxidative stress, inflammation, and bone loss in an experimental periodontal disease model. Material and Methods Male albino Wistar rats were divided into no ligature, ligature, and ligature with 1, 5, and 10 mg/kg gliclazide groups. Maxillae were fixed and scanned usin
J. Appl. Oral Sci.. Publicado em: 21/02/2019