Protective Cardiovascular Effects
Mostrando 1-12 de 50 artigos, teses e dissertações.
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1. Association of CYP2J2 polymorphism with susceptibility to psoriasis in Turkish population: a case-control study,
Abstract Background: Cytochrome P450 2J2 is mostly expressed in extrahepatic tissues; it metabolizes arachidonic acid to epoxyeicosatrienoic acids, with various cardio protective and anti-inflammatory effects. CYP2J2 polymorphism has been identified as a risk factor for cardiovascular diseases, but its association with psoriasis remains unknown. Objective:
An. Bras. Dermatol.. Publicado em: 2020-02
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2. Necrotic xanthogranuloma with disseminated annular lesions,
Abstract Background: Cytochrome P450 2J2 is mostly expressed in extrahepatic tissues; it metabolizes arachidonic acid to epoxyeicosatrienoic acids, with various cardio protective and anti-inflammatory effects. CYP2J2 polymorphism has been identified as a risk factor for cardiovascular diseases, but its association with psoriasis remains unknown. Objective:
An. Bras. Dermatol.. Publicado em: 2020-02
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3. Hydrogen sulfide protects H9c2 cardiomyoblasts against H2O2-induced apoptosis
Reactive oxygen species (ROS) are highly reactive chemical species that may cause irreversible tissue damage, and play a critical role in cardiovascular diseases. Hydrogen sulfide (H2S) is a gasotransmitter that acts as a ROS scavenger with cardio-protective effects. In this study, we investigated the cytoprotective effect of H2S against H2O2-induced apoptos
Braz J Med Biol Res. Publicado em: 15/04/2019
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4. Adiponectin is protective against endoplasmic reticulum stress-induced apoptosis of endothelial cells in sepsis
Endoplasmic reticulum (ER) stress is a critical molecular mechanism involved in the pathogenesis of sepsis. Hence, strategies for alleviating this stress may be essential for preventing cardiovascular injuries under sepsis. Adiponectin is secreted by adipocytes and its levels are decreased in sepsis. The purpose of this study was to investigate the protectiv
Braz J Med Biol Res. Publicado em: 14/11/2018
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5. Captopril alleviates hypertension-induced renal damage, inflammation, and NF-κB activation
Hypertensive renal damage generally occurs during the middle and late stages of hypertension, which is typically characterized by proteinuria and renal inflammation. Captopril, an angiotensin-converting enzyme (ACE) inhibitor, has been widely used for therapy of arterial hypertension and cardiovascular diseases. However, the protective effects of captopril o
Braz J Med Biol Res. Publicado em: 03/09/2018
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6. Short-term carcinogenesis evaluation of Casearia sylvestris
Abstract Casearia sylvestris Sw., Salicaceae, is an important medicinal plant widely used in Brazil for the treatment of various cardiovascular disorders. This species was included as of interest by Brazilian Unified Health System. Although preclinical studies described cardiovascular protective effects and apparent absence of toxicity, no studies have evalu
Rev. bras. farmacogn.. Publicado em: 2017-10
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7. Potential benefit of (-)-epigallocatechin-3-gallate for macrovascular complications in diabetes
Vascular problems are the most common complications in diabetes. Substantial evidence from epidemiological and pathophysiological studies show that hyperglycemia is a major risk factor for macrovascular complications in patients with diabetes. (-)-Epigallocatechin-3-gallate (EGCG), the major catechin derived from green tea, is known to exert a variety of car
Braz J Med Biol Res. Publicado em: 17/08/2017
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8. The Effect of PM 10 on Ischemia- Reperfusion Induced Arrhythmias in Rats
ABSTRACT Epidemiological studies show that particulate matter (PM) is the principal instigator of some adverse clinical symptoms involving cardiovascular diseases. PM exposure can increase experimental infarct size and potentiate myocardial ischemia and arrhythmias in experimental MI models such as ischemia-reperfusion (I/R) injury.The present study was aime
Braz. arch. biol. technol.. Publicado em: 28/07/2016
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9. Assessment of endothelial function by flow-mediated dilation in diabetic patients: Effects of physical exercise
Abstract The endothelium is now recognized as an endocrine organ that acts to maintain vascular homeostasis regulating the vascular tone and structure. The endothelial cells synthetize a variety of mediators among them, the main agent is the nitric oxide (NO), a potent vasodilator. NO exerts its protective role preventing leukocyte adhesion and migration, ex
Motriz: rev. educ. fis.. Publicado em: 2016-03
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10. Previous exercise training increases levels of PPAR-α in long-term post-myocardial infarction in rats, which is correlated with better inflammatory response
OBJECTIVE: Exercise is a protective factor for cardiovascular morbidity and mortality, with unclear mechanisms. Changing the myocardial metabolism causes harmful consequences for heart function and exercise contributes to metabolic adjustment modulation. Peroxisome proliferator-activated receptors (PPARs) are also myocardium metabolism regulators capable of
Clinics. Publicado em: 2016-03
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11. Quercetin postconditioning attenuates myocardial ischemia/reperfusion injury in rats through the PI3K/Akt pathway
Quercetin (Que), a plant-derived flavonoid, has multiple benefical actions on the cardiovascular system. The current study investigated whether Que postconditioning has any protective effects on myocardial ischemia/reperfusion (I/R) injury in vivo and its potential cardioprotective mechanisms. Male Sprague-Dawley rats were randomly allocated to 5 groups (20
Braz J Med Biol Res. Publicado em: 24/09/2013
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12. Omega 3 fatty acid for the prevention of cognitive decline and dementia
BACKGROUND: Evidence from observational studies suggests that diets high in omega-3 long-chain polyunsaturated fatty acids (PUFA) may protect people from cognitive decline and dementia. The strength of this potential protective effect has recently been tested in randomized controlled trials. OBJECTIVES: To assess the effects of omega-3 PUFA supplementation f
Sao Paulo Med. J.. Publicado em: 2012