Prostatic Neoplasm
Mostrando 1-11 de 11 artigos, teses e dissertações.
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1. Low grade urothelial carcinoma mimicking basal cell hyperplasia and transitional metaplasia in needle prostate biopsy
ABSTRACT Purpose The vast majority of urothelial carcinomas infiltrating the bladder are consistent with high-grade tumors that can be easily recognized as malignant in needle prostatic biopsies. In contrast, the histological changes of low-grade urothelial carcinomas in this kind of biopsy have not been studied. Materials and Methods We describe the clini
Int. braz j urol.. Publicado em: 2016-04
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2. A review of continuous vs intermittent androgen deprivation therapy: Redefining the gold standard in the treatment of advanced prostate cancer. Myths, facts and new data on a perpetual dispute
Objectives: To review the literature and present new data of continuous androgen deprivation therapy (ADT) vs intermittent androgen deprivation (IAD) as therapies for prostate cancer in terms of survival and quality of life and clarify practical issues in the use of IAD. Materials and Methods: We conducted a systematic search on Medline and Embase databas
Int. braz j urol.. Publicado em: 2014-01
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3. The initial learning curve for open radical prostatectomy / Curva de aprendizado inicial da prostatectomia radical retropúbica
Introduction: The learning curve is a period of skills improvement. Procedures are carried through with longer operating time, high risk of surgical complications and sub optimal functional outcomes. We have analyzed the residentsinitial learning curve in open radical prostatectomy in our institution. Method: Between June of 2006 and January of 2008, 184 ope
Publicado em: 2010
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4. Seleção e caracterização de peptídeos miméticos a proteínas tumorais no estadiamento clínico-patológico do câncer de próstata
Prostate cancer is the second cause of deaths by tumor in men, surpassed only to lung cancer. Currently, PSA (prostate-specific antigen) is clinical test of choice for PCa detection and treatment. However, the limitations of the PSA test such as large number of false positive results and unnecessary biopsies indicate the need for other means of screening for
Publicado em: 2010
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5. Evaluation of polymorphisms of matrix metalloproteinases genes in prostate cancer / Avaliação de polimorfismos dos genes das metaloproteinases da matriz no câncer de próstata
Introduction: Prostate cancer (PCa) is the most frequent tumor in males in Brazil. Research has been directed for the identification of molecular markers that can predict the PCa predisposition and prognosis. Single nucleotide polymorphisms (SNPs) are genome variations, present in a frequency of 1% or more. The matrix metalloproteinases (MMPs) are a family o
Publicado em: 2008
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6. Local staging of prostate cancer with magnetic resonance imaging versus power-Doppler ultrasound : comparison with hystopathological findings / "Estudo comparativo entre ressonância magnética e ultra-sonografia com power-Doppler no estadiamento local do câncer prostático: correlação com resultados anátomo-patológicos"
O adenocarcinoma prostático (ACP) é um tumor freqüente, que ocupa a segunda posição tanto em mortalidade quanto em incidência dentre as neoplasias malignas masculinas. O estadiamento local do ACP, que consiste na avaliação de extensão extracapsular (EEC) e invasão das vesículas seminais, tem importância fundamental na escolha do tratamento adequa
Publicado em: 2004
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7. Efficiency of 6- and 12-punctures biopsies to detect prostate cancer in patients with PSA< 10 ng/mL and normal digital rectal examination
OBJECTIVE: Establish the efficiency of 6- and 12-punctures transrectal ultrasound-guided needle biopsies in low risk patients for prostate cancer. Six-punctures (sextant) biopsies were compared to 12-punctures biopsies, assessing which is the best strategy to detect this neoplasm. MATERIALS AND METHODS: Among 240 patients submitted to prostate biopsy, 54 wit
International braz j urol. Publicado em: 2003-02
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8. Estudo da proteína de choque térmico GRP78 para o desenvolvimento de um sistema de receptor-ligante para o câncer de próstata / Use of the heat-shock protein GRP78 for the development of a receptor-ligand system in prostate cancer
Introduction: Despite the advances in diagnosis and treatment, advanced prostate cancer remains a lethal condition. Improved methods of therapy are needed to reduce the morbidity and mortality rates associated with this disease. The Glucose-regulated protein-78 (GRP78), a stress-responsive heat-shock protein involved in antigen presentation, was recently des
Publicado em: 2003
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9. Pharmacotherapy for benign prostatic hyperplasia.
Benign prostatic hyperplasia is a benign neoplasm of the prostate seen in men of advancing age. Microscopic evidence of the disorder is seen in about 70% of men by 70 years of age, whereas symptoms requiring some form of surgical intervention occur in 30% of men during their lifetime. Although the exact cause of benign prostatic hyperplasia is not clear, it
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10. My approach to intraductal lesions of the prostate gland
The morphologically heterogeneous (intra)ductal lesions of the prostate frequently present a diagnostic challenge, particularly when found within prostate needle biopsies. By current convention, all high‐grade intra‐acinar and intraductal neoplastic lesions of prostatic origin fall under the diagnostic umbrella term: prostatic intraepithelial neoplasm (P
BMJ Group.
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11. Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice
Dual inactivation of PTEN and INK4a/ARF tumor suppressor genes is a common feature observed in a broad spectrum of human cancer types. To validate functional collaboration between these genes in tumor suppression, we examined the biological consequences of Pten and/or Ink4a/Arf deficiency in cells and mice. Relative to single mutant controls, Ink4a/Arf−/�
The National Academy of Sciences.