Prostaglandins
Mostrando 1-12 de 565 artigos, teses e dissertações.
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1. Pre-TAI protocol strategies to increase reproductive efficiency in beef and dairy cows
Abstract Ovulation synchronization protocols are well established in beef and dairy cows. However, the protocol response rate is around 70-90%. In beef cows, factors such as inadequate nutrition and calf presence negatively impact the response of progesterone (P4)/estradiol-based ovulation synchronization protocols by interfering with GnRH release and conseq
Anim. Reprod.. Publicado em: 28/11/2019
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2. Explanation for the signs and symptoms of tooth eruption: mast cells
Resumo Para contribuir com a compreensão dos mecanismos relacionados à sintomatologia e aos sinais associados à erupção dentária, investigou-se a presença de mastócitos nos tecidos pericoronários na fase intraóssea (Grupo 1) e submucosa (Grupo 2), comparando-os entre si e com a mucosa bucal (Grupo 3). Em cada grupo, 14 espécimes foram analisados m
Dental Press J. Orthod.. Publicado em: 20/05/2019
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3. Effect of phospholipase A2 inhibitors during infection caused by Leishmania (Leishmania) amazonensis
Abstract Background: Lipid metabolites play an important role in parasite differentiation and virulence. Studies have revealed that Leishmania sp. uses prostaglandins to evade innate barriers, thus enabling the parasites to survive inside immune cells. Despite the role of the enzyme Phospholipase A2 (PLA2) in prostaglandins production, few studies have inve
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 21/09/2018
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4. Carcinoid syndrome: update on the pathophysiology and treatment
Approximately 30-40% of patients with well-differentiated neuroendocrine tumors present with carcinoid syndrome, which is a paraneoplastic syndrome associated with the secretion of several humoral factors. Carcinoid syndrome significantly and negatively affects patients’ quality of life; increases costs compared with the costs of nonfunctioning neuroendocr
Clinics. Publicado em: 09/08/2018
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5. Hepatoprotective Role of α-Lipoic acid and Thymoquinone in Acetaminophen- Induced Liver Injury: Down-Regulation of COX-2 and flt-1 Expression
ABSTRACT Acetaminophen (APAP) is a widely-used analgesic, while toxic doses of which induce liver injury. Inducible cyclooxygenase-2 (COX-2) is derived prostaglandins which play an anti-inflammatory role in acetaminophen-induced hepatotoxicity. Selective activation of vascular endothelial growth factor (VEGFR1, flt -1) on endothelial cells increased mRNA lev
Braz. arch. biol. technol.. Publicado em: 17/08/2017
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6. Enhanced cyclooxygenase-2 activity leads to intestinal dysmotility following hemorrhagic shock
ABSTRACT PURPOSE: To test whether hemorrhagic shock (HS) increases the Cyclooxygenase-2 (COX-2) expression in the intestine and whether this enhanced COX-2 expression mediates the intestinal dysmotility after HS. METHODS: Male Wistar rats were randomly divided into HS sham group and HS group. At 180 min following HS establishment, the duodenum samples wer
Acta Cir. Bras.. Publicado em: 2015-12
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7. Effects of exercise training on stress-induced vascular reactivity alterations: role of nitric oxide and prostanoids
Background: Physical exercise may modify biologic stress responses. Objective: To investigate the impact of exercise training on vascular alterations induced by acute stress, focusing on nitric oxide and cyclooxygenase pathways. Method: Wistar rats were separated into: sedentary, trained (60-min swimming, 5 days/week during 8 weeks, carrying a 5% body-weigh
Braz. J. Phys. Ther.. Publicado em: 12/06/2015
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8. Treatment with some anti-inflammatory drugs reduces germ tube formation in Candida albicans strains
Candida albicans is an opportunistic dimorphic fungus that inhabits various host mucosal sites. It can cause both superficial and serious systemic disease. Conversion from the yeast to the hyphal form has been associated with increased virulence and mucosal invasiveness. The aim of this study was to investigate the effect of sodium diclofenac and aspirin on
Braz. J. Microbiol.. Publicado em: 2014-12
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9. Arachidonic acid affects biofilm formation and PGE2 level in Candida albicans and non-albicans species in presence of subinhibitory concentration of fluconazole and terbinafine
Candida albicans utilizes arachidonic acid (AA) released during the course of infection (Candidiasis) from phospholipids of infected host cell membranes and synthesizes extracellular prostaglandin(s) which play an important role in hyphae formation and host cell damage. C. albicans biofilms secrete significantly more prostaglandin(s) and evidence suggests t
Braz J Infect Dis. Publicado em: 2014-06
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10. InvestigaÃÃo dos mecanismos de aÃÃo da atividade gastroprotetora de 1,4-cineol em modelos de Ãlcera gÃstrica em camundongos. / Investigation of mechanisms of action of gastroprotective activity of 1,4-cineole in gastric ulcer models in mice.
1,4-Cineol à um monoterpeno Ãter amplamente distribuido, o qual à um dos constituintes responsÃveis pelo odor do limÃo. O objetivo deste trabalho foi avaliar o efeito gastroprotetor de 1,4-Cineol (CIN 100 e 200 mg/Kg) nos modelos de lesÃo induzidas por etanol ou piroxicam em camundongos e, posteriormente, investigar os possÃveis mecanismos de aÃÃo f
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/08/2012
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11. Ciclooxigenase-2 modula in vivo a expressão de marcadores da osteoclastogênese e genes envolvidos no metabolismo ósseo em resposta ao lipopolissacarídeo bacteriano / Ciclooxygenase-2 modulates in vivo the expression of osteoclastiogenesis makers and genes involved in bone metabolism in response to bacterial lipopolysaccharide
During an inflammatory response, several mediators are locally released in order to stimulate cellular and humoral immune response. Through the action of cyclooxygenase and lipoxygenase enzymes structural changes occur in the arachidonic acid chain leading to synthesis of prostaglandins or leukotrienes and lipoxins, respectively. Such mediators are responsib
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/06/2012
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12. Mecanismos envolvidos na ação anti-hiperalgésica do agonista opióide mu no tecido periférico / Mechanisms underlying the anti-hyperalgesic effect of muopioid agonists in the peripheral tissue
Os objetivos deste estudo foram: (1) Verificar se a administração local de prostaglandina E2 (PGE2) no tecido periférico aumenta o efeito anti-hiperalgésico da ativação do receptor opióide mu e se este efeito é mediado por um aumento da expressão de receptor opióide mu (2) Testar se o efeito anti-hiperalgésico da ativação do receptor opióide mu
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2012