Prostaglandin E1
Mostrando 13-24 de 744 artigos, teses e dissertações.
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13. Cellular and molecular studies of the effects of a selective COX-2 inhibitor celecoxib in the cardiac cell line H9c2 and their correlation with death mechanisms
Cardiovascular disease is one of the leading causes of death worldwide, and evidence indicates a correlation between the inflammatory process and cardiac dysfunction. Selective inhibitors of cyclooxygenase-2 (COX-2) enzyme are not recommended for long-term use because of potentially severe side effects to the heart. Considering this and the frequent prescrib
Braz J Med Biol Res. Publicado em: 29/11/2013
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14. Ischemia and reperfusion of rat small intestine using pentoxyfilline and prostaglandin E1
PURPOSE: To investigate the small intestinal tissue alterations in rats submitted to ischemia and tissue reperfusion using pentoxyfilline or prostaglandin E1. METHODS: Thirty five Wistar rats were used, distributed into group control (A) n=10 were submitted to intestinal ischemia and reperfusion during 60 minutes and no one drug have been utilized. In the gr
Acta Cir. Bras.. Publicado em: 2013-11
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15. Participation of cannabinoid receptors in peripheral nociception induced by some NSAIDs
Nonsteroidal anti-inflammatory drugs (NSAIDs) have been used extensively to control inflammatory pain. Several peripheral antinociceptive mechanisms have been described, such as opioid system and NO/cGMP/KATP pathway activation. There is evidence that the cannabinoid system can also contribute to the in vivo pharmacological effects of ibuprofen and indometha
Braz J Med Biol Res. Publicado em: 2012-12
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16. Effects of prostaglandin administration 10 days apart on reproductive parameters of cyclic dairy nulliparous goats
Relataram-se os efeitos da aplicação de prostaglandina sobre características reprodutivas de cabras leiteiras nulíparas cíclicas. Cabras Alpinas (n=9) e Saanen (n=9) receberam duas doses de 22,5mg PGF2a com 10 dias de intervalo. A progesterona plasmática (ng/mL) foi determinada a partir de amostras de sangue coletadas nos dias 0 (primeira dose), 5, 10
Arquivo Brasileiro de Medicina Veterinária e Zootecnia. Publicado em: 2012-04
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17. Follicle-stimulating hormone to substitute equine chorionic gonadotropin in the synchronization of ovulation in Santa Inês ewes
The substitution of equine chorionic gonadotropin (eCG) by follicle-stimulating hormone (FSH) in protocols for synchronization of ovulation in Santa Inês ewes was assessed. Ten females were submitted to the insertion of intravaginal sponges containing 60 mg medroxyprogesterone acetate for 10 days; after this period sponges were withdrawn and the animals wer
Revista Brasileira de Zootecnia. Publicado em: 2012-03
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18. Nanoemulsões como sistemas de liberação parenteral de fármacos
Lipid nanoemulsions have recently been proposed as parenteral delivery systems for poorly-soluble drugs. These systems consist of nanoscale oil/water dispersions stabilized by an appropriate surfactant system in which the drug is incorporated into the oil core and/or adsorbed at the interface. This article reviews technological aspects of such nanosystems, i
Quím. Nova. Publicado em: 2012
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19. Análise do papel da prostaglandina E2 na proliferação, migração e apoptose na linhagem de glioma humano T98G e o efeito do ácido gama-linolênico e ibuprofeno sobre este prostanóide. / Analysis of the role of prostaglandin E2 on proliferation, migration and apoptosis in the T98G human glioma cell line and the effects of gamma - linolenic acid and Ibuprofen on this prostanoid.
Gliomas são tumores do sistema nervoso central e o glioblastoma multiforme (GBM) é sua forma mais comum e de pior prognóstico. A proliferação desordenada, migração estão entre os processos biológicos que conferem ao GBM um comportamento altamente agressivo. O objetivo deste estudo foi analisar in vitro o papel de PGE2 na proliferação, migração e
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/08/2011
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20. Indução de codominância e dupla ovulação e novas abordagens em luteólise de bovinos / Induced codominance and double ovulation and new approaches on luteolysis in cattle
The day-4 ablation model for increasing the incidence of double ovulations in heifers was used for the chapters 2 and 3. In this regard, follicles ≥ 5 mm were ablated at 4 d post-ovulation to induce a prominent FSH surge and a new follicular wave, and two injections of prostaglandin F2α (12 h apart) were given two days later (6 d) to favor ovulati
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/02/2010
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21. Noncrystalline uric acid inhibits proteoglycan and glycosaminoglycan synthesis in distal tubular epithelial cells (MDCK)
Hyperuricemia is associated with renal stones, not only consisting of uric acid (UrAc) but also of calcium oxalate (CaOx). Glycosaminoglycans (GAGs) are well-known inhibitors of growth and aggregation of CaOx crystals. We analyzed the effect of noncrystalline UrAc on GAG synthesis in tubular distal cells. MDCK (Madin-Darby canine kidney) cells were exposed t
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-10
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22. Juveniles versus adults: differences in PGE2 levels in the gingival crevicular fluid during orthodontic tooth movement
This study aimed to investigate age-related changes in the biosynthetic capacity of prostaglandin E2 (PGE2) in the gingival crevicular fluid (GCF) during one month of orthodontic treatment. Twenty-five juvenile subjects (mean age 13 ± 2.1 years) and 23 adults (mean age 24 ± 2.1 years) were included. GCF was collected immediately before the force applicatio
Brazilian Oral Research. Publicado em: 2010-03
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23. Participação da Prostaglandina E2 e seus receptores na proliferação celular do carcinoma epidermóide de cabeça e pescoço / Role of Prostaglandin E2 and its receptors in head and neck squamous cell carcinoma.
O carcinoma epidermóide de cabeça e pescoço (CECP) representa 6ª malignidade mais comum no mundo. Para melhor entender os mecanismos envolvidos na iniciação tumoral, progressão e metástase, é necessária a elucidação dos eventos moleculares que guiam esses processos. É também importante a investigação da interação e modulação das células
Publicado em: 2010
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24. Diagnóstico ultra-sonográfico do momento ovulatório em búfalas (Bubalus bubalis) inseminadas no estro espontâneo e induzido / Ultrasonographical diagnosis of ovulation in buffaloes (Bubalus bubalis) inseminated in spontaneous and induced oestrus
O objetivo deste experimento foi determinar o intervalo entre o início do estro induzido ou espontâneo e a ovulação em fêmeas bubalinas (Bubalus bubalis) com o auxílio da ultra-sonografia, o que permitirá a determinação de um horário mais apropriado para a I.A. pré-fixada. Nos meses de março a junho, outono no sul do Brasil (época reprodutiva do
Publicado em: 2010