Preserve The Human Genome
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Proteção do genoma humano e socioambientalismo : aspectos bioéticos e jurídicos
The build of the socio-environment paradigm is resultant from the comprehension that isolated protection is not possible, implying collective care. The human being, as a biodiversity integrant, is supported by his laws, but also by environment laws. The human genome is unique for each individual and distinguishes itself from the others beings of the same spe
Publicado em: 2009
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2. Patrimônio Genético Humano: Intervenções Genéticas e o direito das futuras gerações
Nos últimos anos o homem adquiriu um conhecimento científico capaz de alterar a composição química dos seres vivos, inclusive o da sua própria espécie. Essa nova realidade vem modificando as relações sociais diante das inéditas possibilidades conseguidas pelo ser humano, em especial no que se refere à técnica de recombinação de genes utilizada
Publicado em: 2005
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3. Evaluating genome dynamics: the constraints on rearrangements within bacterial genomes
Inversions and translocations distinguish the genomes of closely related bacterial species, but most of these rearrangements preserve the relationship between the rearranged fragments and the axis of chromosome replication. Within species, such rearrangements are found less frequently, except in the case of clinical isolates of human pathogens, where rearran
BioMed Central.
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4. Mechanism of human methyl-directed DNA methyltransferase and the fidelity of cytosine methylation.
The properties of the methyl-directed DNA (cytosine-5-)-methyltransferase (EC 2.1.1.37) suggest that it is the enzyme that maintains patterns of methylation in the human genome. Proposals for the enzyme's mechanism of action suggest that 5-methyldeoxycytidine is produced from deoxycytidine via a dihydrocytosine intermediate. We have used an oligodeoxynucleot
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5. Naturally occurring antisense: Transcriptional leakage or real overlap?
Naturally occurring antisense transcription is associated with the regulation of gene expression through a variety of biological mechanisms. Several recent genome-wide studies reported the identification of potential antisense transcripts for thousands of mammalian genes, many of them resulting from alternatively polyadenylated transcripts or heterogeneous t
Cold Spring Harbor Laboratory Press.
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6. Identification and analysis of alternative splicing events conserved in human and mouse
Alternative pre-mRNA splicing affects a majority of human genes and plays important roles in development and disease. Alternative splicing (AS) events conserved since the divergence of human and mouse are likely of primary biological importance, but relatively few of such events are known. Here we describe sequence features that distinguish exons subject to
National Academy of Sciences.
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7. The Exon Splicing Silencer in Human Immunodeficiency Virus Type 1 Tat Exon 3 Is Bipartite and Acts Early in Spliceosome Assembly
Inefficient splicing of human immunodeficiency virus type 1 (HIV-1) RNA is necessary to preserve unspliced and singly spliced viral RNAs for transport to the cytoplasm by the Rev-dependent pathway. Signals within the HIV-1 genome that control the rate of splicing include weak 3′ splice sites, exon splicing enhancers (ESE), and exon splicing silencers (ESS)
American Society for Microbiology.
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8. Establishment and Maintenance of DNA Methylation Patterns in Mouse Ndn: Implications for Maintenance of Imprinting in Target Genes of the Imprinting Center
Ndn is located on chromosome 7C, an imprinted region of the mouse genome. Imprinting of Ndn and adjacent paternally expressed genes is regulated by a regional imprinting control element known as the imprinting center (IC). An IC also controls imprint resetting of target genes in the region of conserved synteny on human chromosome 15q11-q13, which is deleted
American Society for Microbiology.