Post Transcriptional Regulation
Mostrando 13-24 de 317 artigos, teses e dissertações.
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13. Effect of acute iodine administration on the regulation of sodium-iodide symporter (NIS) gene expression in vivo and in vitro studies. / Efeito da administração aguda de iodo na regulação da expressão do gene do co-transportador de sódio-iodeto (NIS) - estudo in vivo e in vitro.
O iodo em excesso promove o efeito Wolff-Chaikoff. Oligominerais já foram descritos como potenciais reguladores da expressão de proteínas. Tornou-se interessante avaliar se o iodo interferiria com a expressão do mRNA da NIS, em curtos períodos de tempo. Foram realizados, em ratos e células (de 30 min24h), estudos de expressão, comprimento de cauda pol
Publicado em: 2008
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14. Regulação da biossíntese de ácidos graxos insaturados durante a ontogenia de sementes de soja / Regulation of the unsaturated fatty acid biosynthesis during the ontogeny of soybean seeds
The fatty acid composition of soybean seeds has a direct impact on its oxidative stability. High levels of polyunsaturated fatty acids such as linoleic and linolenic acids make the oil more susceptible to hydrolytic and oxidative degradation leading to the formation of volatile compounds which alter the quality and flavor of foods. For this reason, there is
Publicado em: 2008
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15. Efeito da inativação do retroelemento Tnt1 na regeneração de plantas de fumo / Retrotransposon Tnt1 inactivation: effect upon regeneration of tobacco plants
Transposable elements are DNA sequences that have the ability of transposition. These elements are divided in two groups according to their transposition mechanism. Those that transpose directly as a DNA molecule are called transposons and those that are dependent on a RNA intermediate are called retrotransposons. Retrotransposons are found in various organi
Publicado em: 2007
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16. Analise funcional do regulador de transcrição do tipo bZIP AtbZIP9 de Arabidopsis thaliana atraves da superexpressão de seus genes alvos / Fucntional characterization of the Arabidopsis thaliana bZIP transcription factor AtbZIP9 by overexpression of its target genes
Transcriptional regulatory factors (TFs) play an important role in controlling growth and development of ali organisms. bZIPs TFs have been described in ali eukaryotes and are characterized by a basic aminoacid rich DNA binding domain and a leucine zipper, responsible for dimerization. bZIPs have been reported to act in several different plantspecific proces
Publicado em: 2007
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17. Caracterização das subunidades catalíticas do proteassoma 20S em cepas de Trypanosoma cruzi susceptíveis e resistentes ao benzonidazol
Chagas disease is caused by Trypanosoma cruzi. According to WHO, in Latin America, 16-18 million people is infected with this protozoan. Due the involvement of the proteasome in the cellular biology of the T. cruzi and the low efficiency of the drugs used in the individuals treatment with Chagas disease, we believed that the characterization of the catalytic
Publicado em: 2007
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18. Efeito do PSI na inibição do proteassoma 20S de Trypanosoma cruzi
In recent decades the proteases of protozoa parasites have emerged as potential therapeutic targets. One of them, the 20S proteasome, is a self-compartimentalizing protease that plays a crucial role in cell biology regulating several cellular processes including proteins degradation, cell-cycle control, and antigens presentation. In this sense, the main obje
Publicado em: 2007
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19. Identification of differentially expressed genes in queen and worker castes of Melipona quadrifasciata / Identificação de genes diferencialmente expressos nas castas da rainha e operaria de Melipona quadrifasciata
Caste polyphenism is a multifaceted phenomenon, most evident in the marked differences in reproductive capacity and longevity between queens and workers. In the present study, the stingless bee Melipona quadrifasciata anthidioides was chosen to investigate differences in gene expression between newly emerged adult queens and workers. This study has focused o
Publicado em: 2005
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20. Proteina desacopladora de plantas : efeito do estresse oxidativo na sua expressão e atividade e reconstituição funcional da isoforma de Arabidopsis thaliana
The present work is divided in two parts: the functional reconstitution of the Arabidopsis thaZiana uncoupling protein 1 (AtPUMPI) and the expression and activity of the uncoupling protein under several abiotic stresses. AtPUMPI expression in Saccharomyces cerevisae and Escherichia coZi allowed us to confirm that this gene codes for a true uncoupling protein
Publicado em: 2003
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21. Transcriptional and post-transcriptional regulation of storage protein gene expression in sulfur-deficient pea seeds.
We have used in vitro transcription in isolated pea nuclei to determine whether the expression of genes for the seed storage proteins legumin and vicilin is regulated transcriptionally or post-transcriptionally in response to changing sulfur status in the developing seed. During the first 48 h of recovery from S deficiency, transcription of legumin genes inc
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22. Post-transcriptional regulation of pro-inflammatory gene expression
The cytokine tumour necrosis factor (TNF)α is a vital mediator of the innate immune response, and a pleiotropic regulator of cellular function. Its involvement in rheumatoid arthritis is illustrated by the clinical benefits of TNFα blockade. Post-transcriptional regulation (the control of mRNA stability and translation) appears to play a critical role in t
BioMed Central.
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23. Post-transcriptional regulation of nitrate reductase by light is abolished by an N-terminal deletion.
Higher plant nitrate reductases (NRs) carry an N-terminal domain whose sequence is not conserved in NRs from other organisms. A gene composed of a full-length tobacco NR cDNA with an internal deletion of 168 bp in the 5' end fused to the cauliflower mosaic virus 35S promoter and appropriate termination signals was constructed and designated as delta NR. An N
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24. Transcriptional and post-transcriptional regulation of c-myc expression during the differentiation of murine erythroleukemia Friend cells.
c-myc RNA rapidly decreases to barely detectable levels in Friend erythroleukemia cells induced to differentiate upon the addition of dimethylsulfoxide. We show here that c-myc gene is down-regulated both at the transcriptional level presumably by a block in the elongation of primary transcripts and at the post-transcriptional level by an increase in the deg