Porin
Mostrando 1-12 de 529 artigos, teses e dissertações.
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1. Detection and analysis of different interactions between resistance mechanisms and carbapenems in clinical isolates of Klebsiella pneumoniae
Abstract Carbapenems are considered last-line agents for the treatment of serious infections caused by Klebsiella pneumoniae, and this microorganism may exhibit resistance to β-lactam antibiotics due to different mechanisms of resistance. We evaluated 27 isolates of K. pneumoniae resistant to carbapenems recovered from inpatients at the University Hospital
Braz. J. Microbiol.. Publicado em: 2017-07
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2. Carbapenem-resistant and cephalosporin-susceptible: a worrisome phenotype among Pseudomonas aeruginosa clinical isolates in Brazil
Abstract The mechanisms involved in the uncommon resistance phenotype, carbapenem resistance and broad-spectrum cephalosporin susceptibility, were investigated in 25 Pseudomonas aeruginosa clinical isolates that exhibited this phenotype, which were recovered from three different hospitals located in São Paulo, Brazil. The antimicrobial susceptibility profil
Braz J Infect Dis. Publicado em: 2017-02
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3. Whole genome sequence of Klebsiella pneumoniae U25, a hypermucoviscous, multidrug resistant, biofilm producing isolate from India
Klebsiella pneumoniae U25 is a multidrug resistant strain isolated from a tertiary care hospital in Chennai, India. Here, we report the complete annotated genome sequence of strain U25 obtained using PacBio RSII. This is the first report of the whole genome of K. pneumoniaespecies from Chennai. It consists of a single circular chromosome of size 5,491,870-bp
Mem. Inst. Oswaldo Cruz. Publicado em: 2016-02
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4. Carbapenem and cefoxitin resistance of Klebsiella pneumoniae strains associated with porin OmpK36 loss and DHA-1 β-lactamase production
Clinical isolates of carbapenem-resistant Klebsiella pneumoniae (K. pneumoniae) strains are being increased worldwide. Five pan-resistant K. pneumoniae strains have been isolated from respiratory and ICU wards in a Chinese hospital, and reveal strong resistance to all β-lactams, fluoroquinolones and aminoglycosides. Totally 27 β-lactamase genes and 2 membr
Braz. J. Microbiol.. Publicado em: 2013
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5. Análise molecular de mecanismos determinantes de resistência a antibióticos em Pseudomonas aeruginosa e Acinetobacter ssp. / Molecular evaluation of the mechanisms that determine antimicrobial resistance in Pseudomonas aeruginosa and Acinetobacter spp.
P. aeruginosa e espécies de Acinetobacter são causas comuns de diversas infecções em pacientes hospitalizados, principalmente nos internados em centros de tratamento intensivo. Além disso, esses microrganismos se destacam por apresentarem resistência, intrínseca e adquirida, a várias classes de antibióticos, conferindo à bactéria fenótipos de mul
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/08/2011
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6. Alterações da permeabilidade e expressão de bombas de efluxo em isolados clínicos de Pseudomonas aeruginosa resistente ao imipenem / Permeability alterations and expression of efflux pumps in clinical isolates of imipenem-resistant Pseudomonas aeruginosa
Introdução: Isolados clínicos de Pseudomonas aeruginosa multirresistentes estão associados a elevadas taxas de mortalidade. A resistência ao imipenem é uma urgência global, uma vez que é considerado o tratamento de escolha para infecções associadas a bactérias Gram negativas multirresistentes. Assim, elucidar os mecanismos de resistência é de vi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/10/2010
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7. Estudo epidemiologico-molecular e da resistencia ao imipenem, ocasionda pela perda de canais de porina, em Pseudomonas aeruginosa isolada de pacientes hospitalizados / Study epidemiologist-molecullar and of the resistance to the imipenem, caused for the loss of porin canals, in isolated aeruginosa Pseudomonas of hospitalized patients
Introdução: A Pseudomonas aeruginosa é um importante agente de infecção nosocomial e motivo de grande preocupação por apresentar, com freqüência, resistência a diversos antimicrobianos. Os principais mecanismos de resistência encontrados são: inativação por enzimas, alterações na permeabilidade da membrana celular e promoção de efluxo. O co
Publicado em: 2007
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8. Partial purification of tightly bound mitochondrial hexokinase from maize (Zea mays L.) root membranes
In mammals, hexokinase (HK) is strategically located at the outer membrane of mitochondria bound to the porin protein. The mitochondrial HK is a crucial modulator of apoptosis and reactive oxygen species generation. In plants, these properties related to HK are unknown. In order to better understand the physiological role of non-cytosolic hexokinase (NC-HK)
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-09
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9. Klebsiella pneumoniae with multiple antimicrobial resistance
A Klebsiella pneumoniae strain was isolated from the urine of a patient at one of the centers participating in the 2001 edition of the MYSTIC program in Brazil. The initial phenotypic findings of the isolated K. pneumoniae presented an unusual MIC of 8 mug/mL to meropenem, 2 mug/mL to imipenem, elevated MICs to broad spectrum cephalosporins (ceftazidime/cefo
Brazilian Journal of Infectious Diseases. Publicado em: 2004-02
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10. Immunological properties of recombinant porin of Haemophilus influenzae type b expressed in Bacillus subtilis.
The major surface-located, channel-forming protein in the outer membrane of Haemophilus influenzae type b (Hib) is porin (341 amino acids; M(r), 37,782). In order to generate Hib porin that is devoid of lipooligosaccharides and capsular polysaccharide, the Hib porin gene ompP2 was subcloned into a plasmid vector and recombinant Hib porin was expressed in Bac
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11. Mechanism of protective immunity induced by porin-lipopolysaccharide against murine salmonellosis.
Investigations were undertaken to characterize the protective immunity induced by porin-lipopolysaccharide (LPS) against Salmonella typhimurium infection in mice. Mice immunized with porin-LPS showed higher levels of antiporin immunoglobulin G than mice which received porin alone. Further, T cells from porin-LPS-immunized mice showed an augmented proliferati
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12. Porin activity in the osmotic shock fluid of Escherichia coli.
Osmotic shock fluid of Escherichia coli exhibited pore-forming activity. This activity could be followed by an in vitro assay based on the conductivity increase for ions due to the presence of pores in black lipid membranes. The histogram (the distribution of conductivity increments in a single pore experiment) obtained with osmotic shock fluid from E. coli