Ponies
Mostrando 13-24 de 49 artigos, teses e dissertações.
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13. Clinical, histopathological, and immunological responses of ponies to Ehrlichia sennetsu and subsequent Ehrlichia risticii challenge.
Ehrlichia risticii has a close antigenic relationship to E. sennetsu. Sera of ponies experimentally infected with E. risticii, the etiologic agent of Potomac horse fever, consistently reacted with E. sennetsu, a human pathogen, in indirect fluorescent-antibody (IFA) testing, while human E. sennetsu convalescent serum reacted with E. risticii by IFA testing a
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14. Causative ehrlichial organisms in Potomac horse fever.
An ehrlichia was consistently isolated from the peripheral blood leukocyte fraction of ponies that had been experimentally infected with Potomac horse fever by whole blood transfusion from naturally infected horses. The organism was propagated in a human histiocyte cell line for 3 to 5 weeks and then inoculated intravenously or intradermally into healthy adu
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15. Complement requirement for virus neutralization by antibody and reduced serum complement levels associated with experimental equine herpesvirus 1 infection.
Pony foals, negative for detectable serum-neutralizing antibody to equine herpesvirus 1 by the standard tube-culture virus neutralization test, were experimentally infected with equine herpesvirus 1. Complement-requiring (CR) and non-complement-requiring (NCR) serum-neutralizing antibodies were evaluated in preinfection and postinfection sera by means of a c
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16. Effect of prednisolone on the leukocyte counts of ponies and on the reactivity of lymphocytes in vitro and in vivo.
Treatment of ponies with a single dose of prednisolone markedly reduced the number of blood lymphocytes. A decrease of the number of eosinophils was also observed. In contrast, the number of neutrophils significantly increased. These profound changes were temporary and returned to the pretreatment level within 48 h. The number of monocytes did not show any o
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17. Efficacy of inactivated whole-virus and subunit vaccines in preventing infection and disease caused by equine infectious anemia virus.
We report here on a series of vaccine trials to evaluate the effectiveness of an inactivated equine infectious anemia virus (EIAV) whole-virus vaccine and of a subunit vaccine enriched in EIAV envelope glycoproteins. The inactivated vaccine protected 14 of 15 immunized ponies from infection after challenge with at least 10(5) 50% tissue culture-infective dos
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18. Equine infectious anemia virus replication is upregulated during differentiation of blood monocytes from acutely infected horses.
Equine infectious anemia virus is a lentivirus that replicates in mature tissue macrophages of horses. Ponies were infected with equine infectious anemia virus. During febrile episodes, proviral DNA was detectable, but viral mRNA was not detectable. As cultured blood monocytes from these ponies differentiated into macrophages, viral expression was upregulate
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19. Temporal effects of freezing on plasma nitric oxide concentrations in ponies
The purpose of this study was to compare concentrations of nitric oxide (NO) in fresh plasma versus frozen plasma, and determine the temporal effects of freezing on jugular venous plasma NO concentrations in clinically healthy ponies. Twenty-eight helminth-naïve ponies, aged from 4 to 6 mo, were raised and maintained under parasite-free conditions. Blood wa
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20. Left ventricular oxygen extraction during submaximal and maximal exertion in ponies.
1. Left ventricular (LV) myocardial O2 extraction was studied in five healthy ponies which had catheters implanted in the great cardiac vein and main pulmonary artery 15-30 days before the study. The abdominal aorta was percutaneously catheterized to sample arterial blood. 2. In addition, phasic LV and aortic pressures, LV dP/dtmax and rate-pressure product
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21. Genomic quasispecies associated with the initiation of infection and disease in ponies experimentally infected with equine infectious anemia virus.
Equine infectious anemia virus (EIAV) provides a uniquely dynamic system in which to study the mechanism and role of genomic variation in lentiviral persistence and pathogenesis. We have used a Shetland pony model of infection to investigate the association of specific long terminal repeat (LTR) and env gene genomic sequences with the initiation of infection
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22. Blood flow to the respiratory and limb muscles and to abdominal organs during maximal exertion in ponies.
Using radionuclide-labelled microspheres, 15 micron in diameter, we studied blood flow in the respiratory muscles (diaphragm and intercostal muscles), abdominal organs (adrenal glands, kidneys, pancreas, spleen and the small and large intestines), muscles of propulsion (gluteus medius and biceps femoris), and other working (triceps brachii and longissimus do
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23. Immune Responses and Viral Replication in Long-Term Inapparent Carrier Ponies Inoculated with Equine Infectious Anemia Virus
Persistent infection of equids by equine infectious anemia virus (EIAV) is typically characterized by a progression during the first year postinfection from chronic disease with recurring disease cycles to a long-term asymptomatic infection that is maintained indefinitely. The goal of the current study was to perform a comprehensive longitudinal analysis of
American Society for Microbiology.
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24. Role of Cerebrospinal Fluid [H+] in Ventilatory Deacclimatization from Chronic Hypoxia
Once ventilatory acclimatization begins in sea level residents sojourning at high altitude, abrupt restoration of normal oxygen tensions will not restore ventilation to normal. We have investigated the role of cerebrospinal fluid (CSF) [H+] in this sustained hyperventilation by measuring CSF acid-base status in seven men (lumbar) and five ponies (cisternal)