Polar Compounds
Mostrando 13-24 de 195 artigos, teses e dissertações.
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13. Phenolic compounds from Virola venosa (Myristicaceae) and evaluation of their antioxidant and enzyme inhibition potential
Resumo Virola venosa, popularmente conhecida como ucuuba-da-mata, ocorre naturalmente na região amazônica e tem potencial para fornecer compostos naturais úteis, como já foi mostrado para outras espécies de Virola. Por isso, o objetivo deste estudo foi determinar a composição química dos extratos do tronco e das folhas de V. venosa e os possíveis po
Acta Amaz.. Publicado em: 2019-03
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14. A new tricyclic abietane diterpenoid from Salvia chloroleuca and evaluation of cytotoxic and apoptotic activities
Abstract In this study, sahandone (1) and a new diterpenoid named sahandol II (2) were isolated from the roots of Salvia chloroleuca Rech. f. & Aellen, Lamiaceae. The absolute configurations of compounds 1 and 2 were assigned by comparison of experimental electronic circular dichroism spectra and comparing with published data. Cytotoxic and apoptotic evaluat
Rev. bras. farmacogn.. Publicado em: 2019-02
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15. SYNTHESIS, ELECTRONIC AND SPECTRAL PROPERTIES OF NEW 1,3,4-THIADIAZOLE COMPOUNDS AND THE SPECTRAL ANALYSIS OF THEIR CONFORMERS USING DENSITY FUNCTIONAL THEORY
In this study, new 1,3,4-thiadiazole compounds were synthesised and characterised by FT-IR, 1H-NMR, UV-vis spectroscopy and elemental analysis, Furthermore, the relationship between the electronic and spectral data of the 16 conformers of each compound was investigated by theoretical calculations; the theoretical data were compared with the experimental resu
Quím. Nova. Publicado em: 2019-02
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16. Investigation of Distribution of Antioxidant Compounds from Natural Sources and Study of Lipid Protection in Oil-in-Water Emulsions
The investigation of the distribution of antioxidant compounds between emulsions phases, employing natural sources of these compounds directly in the emulsions, is rarely addressed. The use of ultra performance liquid chromatography coupled to a mass spectrometer (UPLC-MS), combined with accelerated oxidation tests and oxygen radical absorbance capacity meth
J. Braz. Chem. Soc.. Publicado em: 2018-08
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17. Polydimethylsiloxane as a Matrix for the Stabilization and Immobilization of Zero-Valent Iron Nanoparticles. Applications to Dehalogenation of Environmentally Deleterious Molecules
A wet-synthetic method is described to obtain magnetic, air-stable, zero-valent iron nanoparticles coated with an alkanedioic acid. The particles can be immobilized in an amino-substituted polysiloxane matrix to provide materials capable of dechlorinating, debrominating, and deiodinating a wide variety of halogenated organic molecules dissolved initially in
J. Braz. Chem. Soc.. Publicado em: 2018-07
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18. MÉTODOS AMBIENTALMENTE AMIGÁVEIS PARA A IODAÇÃO REGIOSSELETIVA DA 3,7,3’,4’-TETRAMETOXI-QUERCETINA
Halogenated compounds are valuable substrates for the field of organic synthesis and more specifically as reagents for coupling reactions. Environmental friendly procedures for regioselective iodination is the aim of this study, using four different methods previously described in the literature, that embrace green chemistry concepts, to obtain the 6- and 8-
Quím. Nova. Publicado em: 2018-05
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19. PHENOLIC DERIVATIVES AND ANTIOXIDANT ACTIVITY OF POLAR EXTRACTS FROM Bauhinia pulchella
A tea made with the leaves or stem bark of Bauhinia pulchella Benth (Fabaceae) is used in the treatment of diabetes. Ethanol (EEF) and aqueous (EAF) extracts were obtained from the leaves and the antioxidant and citotoxic activities were tested, as well as quantify the content of flavonoids and phenolic compounds (TPC). EEF and EAF showed similar profiles by
Quím. Nova. Publicado em: 2018-04
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20. Anti-Trypanosoma Activity and Synergistic Effects of Natural and Semi-Synthetic Triterpenes and Predominant Cell Death through Autophagy in Amastigote Forms
Chagas' disease is a parasitic disease with unsatisfactory treatment, mainly in chronic stage. This study aimed to evaluate the trypanocidal activity and action mechanisms of α/β-amyrin and its semi-synthetic derivatives, together with four isolated natural triterpenes, tested against trypomastigote and amastigote forms. The structure-activity relationship
J. Braz. Chem. Soc.. Publicado em: 2017-12
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21. Anti-adhesion potential of non-polar compounds and extracts from Ficus natalensis
Abstract Four triterpenoids, ergosta-4,6,8(14),22-tetraene-3-one 1, stigma-4-ene-3-one 2, 3β-hydroxy-21β-H-hop-22(29)-ene 3, sitosterol and a quinone, tectoquinone 4, were isolated from the leaf, stem bark and fruit extracts of Ficus natalensis subsp. natalensis, Moraceae, a medicinal fig found in Africa. The pure compounds 1–4 and crude extracts were te
Rev. bras. farmacogn.. Publicado em: 2017-10
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22. Schinus terebinthifolius: phenolic constituents and in vitro antioxidant, antiproliferative and in vivo anti-inflammatory activities
ABSTRACT Schinus terebinthifolius Raddi, Anacardiaceae, native to Brazil, is referred to as "pimento-rosa" and is used to treat inflammatory disease in folk medicine. Studies have reported important pharmacological properties, but these effects have still not been fully exploited. This study reports that the crude extract and isolated compounds of S. terebin
Rev. bras. farmacogn.. Publicado em: 2017-08
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23. EQUILÍBRIO QUÍMICO E CINÉTICA ENZIMÁTICA DA INTERAÇÃO DE α-AMILASE COM COMPOSTOS FENÓLICOS ENCONTRADOS EM CERVEJA
α-amylase is a key enzyme in the production of beer due to the breakdown of starch into fermentable sugars. During the preparation of the brewing mash, the enzyme can be affected by polyphenols present in the mixture. Our aim was to evaluate the kinetics and equilibrium of the interaction of α-amylase with some polyphenols (chlorogenic, caffeic, ferulic ac
Quím. Nova. Publicado em: 2017-08
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24. Special metabolites isolated from Urochloa humidicola (Poaceae)
ABSTRACT This study aims to identify special metabolites in polar extracts from Urochloa humidicola (synonym Brachiaria humidicola) that have allelopathic effects and induce secondary photosensitization in ruminants. The compounds were isolated and identified via chromatographic and spectroscopic techniques. The compounds 4-hydroxy-3-methoxy-benzoic acid, tr
An. Acad. Bras. Ciênc.. Publicado em: 2017-06