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Mostrando 1-12 de 3617 artigos, teses e dissertações.
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1. Enthesitis-related arthritis: monitoring and specific tools
Abstract Objective: In this article, the authors aimed to review the different tools used in the monitoring of enthesitis-related arthritis. Sources: The authors performed a literature review on PubMed, Google Scholar, and Scopus databases. The dataset included the original research and the reviews including patients with enthesitis-related arthritis or ju
Jornal de Pediatria. Publicado em: 2022
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2. DESVENDANDO UM CASO: QUANDO ESTUDANTES SE TORNAM PERSONAGENS DE UMA HISTÓRIA NA DISCIPLINA DE QUÍMICA ORGÂNICA EXPERIMENTAL
Being part of the Pharmacy course curriculum, Organic Chemistry emphasizes the fundamentals of Organic Synthesis, reaction mechanisms, as well as the methods for separation, purification and identification of organic compounds. However, students do not always realize the direct association between this knowledge and their future working field. In an effort t
Química Nova. Publicado em: 2022
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3. Oxidative Stress and Changes of Important Metabolic Gene Expressions as a Potential Biomarker in the Diagnosis of Atherosclerosis in Leukocytes
ABSTRACT Introduction: Presenilin 1 (PSEN1), catalase (CAT), glutathione-S-transferase (GST) and paraoxonase 1 (PON1) play a vital role in prediction, diagnosis and therapy of metabolic disorders. Methods: Metabolic enzyme activities and lipid peroxidation in serum of cerebrovascular diseases (CVD) and coronary artery diseases were measured by spectrophoto
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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4. Serum Long-Noncoding RNA H19 and β-Catenin as Biomarkers for Early Diagnosis of Colorectal Cancer in Egyptian Patients: A Case Control Study
Abstract Colorectal cancer (CRC) is the third most prevalent cancer and the second most common cause of cancer death; however, its early detection can improve the survival. Colonic polyps are considered one of the CRC's major risk factors. Throughout many biological processes and malignancies, the non-coding RNAs have essential functions. Certain long noncod
Journal of Coloproctology (Rio de Janeiro). Publicado em: 2022
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5. Association of FOXO3 polymorphism (rs3800231) and clinical subphenotypes of beta thalassemic individuals
Abstract Introduction Studies have shown that the loss of the FOXO3 transcriptional function is involved in the pathophysiology of some chronic erythroid disorders, including beta-thalassemia (β-thal). Therefore, the single nucleotide polymorphism (SNP) rs3800231 (35-2764A > G) could contribute to alterations in its transcriptional activity, acting as a mo
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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6. Fatty acid-binding protein 4 circulating levels in non-segmental vitiligo
Abstract Background: Vitiligo is an acquired and progressive mucocutaneous disease resulting from the loss of active epidermal melanocytes. Metabolic syndrome (MetS) affects about 25% of the world’s population and is linked to inflammatory skin diseases including vitiligo. Fatty AcidBinding Protein 4 (FABP4) is an intracellular lipid chaperone. FABP4 is c
Anais Brasileiros de Dermatologia. Publicado em: 2022
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7. Avaliação de uso de parques por meio de protocolos da saúde pública: um estudo comparativo
Resumo Estudos têm apontado o importante papel dos espaços públicos como suporte para uma vida mais saudável. O objetivo da pesquisa foi verificar a existência de associação entre as configurações espaciais de parques localizados em áreas socioeconômicas distintas com a prática de atividade física. A estratégia metodológica foi a de estudo de
Ambient. constr.. Publicado em: 2021-04
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8. Blood microRNA expressions in patients with mild to moderate psoriasis and the relationship between microRNAs and psoriasis activity,
Abstract Background: In recent studies, microRNAs (mi-RNAs) have been shown to play an important role in psoriasis pathogenesis. However, studies evaluating mi-RNAs in the blood of psoriasis patients including a large number of mi-RNA panels are scarce. Objective: The authors aimed to assess mi-RNA expressions in blood samples of psoriasis patients, as wel
An. Bras. Dermatol.. Publicado em: 2020-12
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9. New Synthetic Quinolines as Cathepsin K Inhibitors
Cathepsin K is a papain-like cysteine protease and is responsible for collagen degradation in bone tissue and thus represents an important target for the development of new therapies for treating diseases such as osteoporosis. Quinolines are an important class of heterocyclic molecular leads with a great pharmacological potential and represent a relevant sca
J. Braz. Chem. Soc.. Publicado em: 2020-08
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10. Reabilitação com uso de realidade virtual: atividade física para pacientes admitidos na unidade de terapia intensiva
RESUMO Objetivo: Avaliar o nível de atividade que o uso do videogame Nintendo WiiTM pode provocar em pacientes na unidade de terapia intensiva, além dos níveis de segurança do método e da satisfação do paciente. Métodos: Ensaio experimental em centro único conduzido em um hospital terciário. Incluíram-se pacientes com idade igual ou superior a 1
Rev. bras. ter. intensiva. Publicado em: 20/01/2020
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11. Cytotoxic Activity of Synthetic Chiral Amino Acid Derivatives
Cancer is a chronic degenerative disease considered one of the most important causes of death worldwide. In this context, a series of dual-protected amino acid derivatives was synthesized and evaluated as potential novel anticancer agents. The 40 derivatives were prepared in up to three reaction steps. The cytotoxic activities were screened in vitro against
J. Braz. Chem. Soc.. Publicado em: 2020-01
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12. Antioxidant potential of various solvent extract from Morus alba fruits and its major polyphenols composition
RESUMO: As condições de extração são um fator importante no processo de obtenção de compostos bioativos da matriz vegetal. Estes compostos diferem-se estruturalmente. As estruturas de fito conjugações e suas interações com outros ingredientes alimentares não são totalmente conhecidas, enquanto esses dois aspectos devem desempenhar um papel sign
Cienc. Rural. Publicado em: 13/12/2019