Piperolideos
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1. Evaluation of biological potential of natural piperolídeos of Piper malacophyllum (C. Presl) C. DC. and synthetic analogues / Avaliação do pontencial biológico de piperolídeos naturais de Piper malacophyllum (C. Presl) C. DC. e de análogos sintéticos
Based on the powerful antifungal activity of piperolides (1 e 2) isolated from Piper malacophyllum leaves extracts, several analogues were synthesized aiming at establishing preliminary structure-activity relationship against Cladosporium cladosporioides, C. sphaerospermum and against epimastigote form of Trypanosoma cruzi. Phytochemical studies carried out
Publicado em: 2008