Photosensitizers
Mostrando 1-12 de 69 artigos, teses e dissertações.
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1. EXPERIMENTAL STUDY OF THE NEUROTOXIC EFFECTS OF PHOTODYNAMIC THERAPY ON THE SPINAL CORD
RESUMO Objetivo Avaliar os efeitos da terapia fotodinâmica (PDT) na dura-máter usando os fotossensibilizadores cloreto de alumínio ftalocianina e azul de metileno em ensaios in vivo. Métodos Cinquenta e seis ratos Wistar machos divididos em dois grupos; um submetido à PDT e o outro submetido aos fotossensibilizadores sem a fotoativação (controle). O
Coluna/Columna. Publicado em: 02/09/2019
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2. ATIVIDADE FOTODINÂMICA E CONCEITOS: UM EXPERIMENTO DEMONSTRATIVO
A simple and low cost experiment is proposed to chemistry students associating the Photodynamic Activity involving Chemical and Biochemical concepts. The inclusion of this experiment in undergraduate courses in Chemistry promotes interdisciplinarity and contextualization, combining current and relevant topics to the teaching of program content. The experimen
Quím. Nova. Publicado em: 2018-06
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3. An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy
ABSTRACT Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are destroyed by reactive oxygen species (ROS) produced by photosensitizers following its activation with visible or near infrared light. The PDT success is dependent on different factors namely on the efficiency of the photosensitizer deliver and targeting ability. In
An. Acad. Bras. Ciênc.. Publicado em: 2018
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4. Cancer, Photodynamic Therapy and Porphyrin-Type Derivatives
ABSTRACT This review has two parts. The first one gives an approach to interdisciplinary studies against cancer carried out by many scientists using porphyrin-type substrates as photosensitizers in PDT. Intensive studies were performed for almost six decades. The successes really started in 1993 with the first formulation patented under the trade name Photof
An. Acad. Bras. Ciênc.. Publicado em: 2018
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5. Bacterial Cellulose Membranes as a Potential Drug Delivery System for Photodynamic Therapy of Skin Cancer
The development of drug delivery systems for photodynamic therapy (PDT) is increasingly demanded due to the hydrophobicity presented by most of photosensitizers molecules. Bacterial cellulose (BC), a highly pure cellulose produced by bacteria, possesses the essential features for applications in drug delivery systems, such as large surface area and excellent
J. Braz. Chem. Soc.. Publicado em: 2016-11
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6. Chlorophyllin Derivatives as Photosensitizers: Synthesis and Photodynamic Properties
Two new photosensitizers (PSs) derived from copper-chlorophyllin were designed to have excitation wavelengths appropriate for the use in photodynamic therapy (PDT) and to have amphiphilic character with positive charge, which favors binding to cell membranes and walls and the intracellular localization in mitochondria. Herein we describe the synthesis and ch
J. Braz. Chem. Soc.. Publicado em: 2015-12
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7. Pyranoflavylium derivatives extracted from wine grape as photosensitizers in solar cells
Derivados piranoflavinílicos, nomeadamente cianidina-3-glucósido, malvidina 3-O-glucósido, malvidina 3-O-comaroilglucósido, derivado pirúvico da cianidina-3-glucósido e derivado pirúvico da malvidina-3-glucósido, extraídos de uvas tintas foram usados como sensibilizadores em células solares sensibilizadas por corantes (DSSCs). Com estes corantes na
J. Braz. Chem. Soc.. Publicado em: 2014-06
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8. The susceptibility of Streptococcus mutans to antibacterial photodynamic therapy: a comparison of two different photosensitizers and light sources
Streptococcus mutans is the main etiological agent for dental caries. Recently, photodynamic therapy (PDT) has been introduced as a new modality in bacterial decontamination. Objective: This in vitro study was carried out to evaluate the susceptibility of Streptococcus mutans to antibacterial PDT using two different photosensitizers and light sources.
J. Appl. Oral Sci.. Publicado em: 2014-04
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9. Avaliação de fármacos fotossensíveis derivados da cloro alumínio ftalocianina no tratamento da progressão tumoral em modelo de matriz tridimensional mista / Evaluation of photosensitizers aluminum chloride phthalocyanine derivatives in the treatment of tumor progression in three-dimensional matrix.
Wound healing process can be favored by Low Level Laser Therapy, with the collagen and elastin matrix a dermic substitute described as an appropriate system in tissue engineering and in tridimensional skin systems. With this purpose, a study was elaborated using the system nanoemulsion of aluminium-chloride phthalocyanine (ClAlPc) as photosensitizer in skin
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/10/2012
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10. Inativação fotodinâmica de conídios dos fungos Aspergillus nidulans, Colletotrichum acutatum e Colletotrichum gloeosporioides com fotossensibilizadores fenotiazínicos e cumarínicos / Photodynamic inactivation of conidia of the fungi Aspergillus nidulans, Colletotrichum acutatum and Colletotrichum gloeosporioides with phenothiazinium and coumarinium photosensitizers
O tratamento fotodinâmico antifúngico (APDT) é um método promissor que combina um fotossensibilizador não tóxico (FS), oxigênio e luz visível para provocar a morte seletiva das células microbianas. O desenvolvimento do APDT depende da identificação de FS que sejam eficazes para as diferentes espécies de patógenos. No presente estudo, as suscetib
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/08/2012
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11. Photodynamic therapy of Pythium insidiosum inactivation in vitro and in vivo study / Terapia fotodinâmica para inativação do Pythium insidiosum - estudo in vitro e in vivo
Photodynamic Therapy (PDT) is a therapy based on the interaction of photosensitizer and light, in the presence of oxygen, to induce cellular death. Under the incidence of light, at an appropriated wavelength, these chemical compounds produce reactive oxygen species which affects the biomolecules of the target-cells. Pythiosis is a lifethreatening emerging di
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/08/2012
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12. STUDY OF THE INTERACTION OF PHTHALOCYANINE-DERIVED PHOTOSENSITIZERS WITH DRUG DELIVERY SYSTEMS FOR PHOTODYNAMIC THERAPY / ESTUDO DA INTERAÇÃO DE FOTOSSENSIBILIZANTES DERIVADOS DE FTALOCIANINAS COM SISTEMAS DE DISTRIBUIÇÃO DE FÁRMACOS PARA TERAPIA FOTODINÂMICA
A Terapia Fotodinâmica (PDT) consiste na irradiação com luz visível de um tecido após a aplicação de um fotossensibilizante. São produzidas diferentes espécies reativas, em especial oxigênio singleto, que desencadeiam uma série de eventos que resultam na inativação ou morte celular. O desenvolvimento de fotossensibilizantes e o estudo de sua dis
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/04/2012