Photosensitizer
Mostrando 13-24 de 85 artigos, teses e dissertações.
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13. Bifunctional Porous SiO2 Complex Nanoparticles with Properties of Enzymatic Catalysis and Optical Oxygen Sensing
The porous fluorescent SiO2 nanoparticles encapsulating photosensitizer Ru(bpy)3Cl2were prepared by Stöber method and used as a carrier to immobilize glucose oxidase (GOD) to form the bifunctional porous SiO2 complex nanoparticles (BPSCNp) with the properties of enzymatic catalysis and optical oxygen sensing. The optimal immobilization conditions are as fol
J. Braz. Chem. Soc.. Publicado em: 2015-09
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14. SPECTROSCOPIC STUDY OF ALUMINUM PHTHALOCYANINE CHLORIDE (AlPcCl) IN HOMOGENEOUS AND MICRO-HETEROGENEOUS MEDIA CONSISTING OF P-123 AND F-127 POLYMERIC MICELLES
Aluminum phthalocyanine chloride (AlPcCl) is a photoactive compound which has been used as a photosensitizer (PS) in photodynamic therapy (PDT). Its spectroscopic properties have been studied in solvents of different polarities (ethanol, acetone, dimethylsulfoxide and chloroform). Its solubility has been found to decrease with increasing solvent polarity,
Quím. Nova. Publicado em: 2015-06
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15. The susceptibility of Streptococcus mutans to antibacterial photodynamic therapy: a comparison of two different photosensitizers and light sources
Streptococcus mutans is the main etiological agent for dental caries. Recently, photodynamic therapy (PDT) has been introduced as a new modality in bacterial decontamination. Objective: This in vitro study was carried out to evaluate the susceptibility of Streptococcus mutans to antibacterial PDT using two different photosensitizers and light sources.
J. Appl. Oral Sci.. Publicado em: 2014-04
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16. Physico-chemical properties of meso-tetrakis(p-methoxyphenyl)porphyrin (TMPP) incorporated into pluronicTM p-123 and f-127 polymeric micelles
The physicochemical properties (solubilization, structural organization and stability) of meso-tetrakis(p-methoxyphenyl)porphyrin (TMPP), a promising photosensitizer for photodynamic therapy, solubilized in polymeric micelles of tri-block copolymers PluronicTM P-123 and F-127, were studied. The formulations obtained by the solid dispersion method led to mono
Quím. Nova. Publicado em: 2014
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17. Photodynamic therapy associated with full-mouth ultrasonic debridement in the treatment of severe chronic periodontitis: a randomized-controlled clinical trial
Background: Photodynamic therapy (PDT) is a method of microbial reduction which can benefit periodontal treatment in areas of difficult access, such as deep pockets and furcations. The aim of this randomized controlled clinical trial was to evaluate the effects of PDT as an adjunct to full-mouth ultrasonic debridement in the treatment of severe chronic per
J. Appl. Oral Sci.. Publicado em: 2013-04
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18. Estudos quimiométricos da pheo formulada em pluronics®: ação fotodinâmica Sobre Artemia salina
The self-aggregation of pheophytin, a possible photosensitizer for Photodynamic Therapy, is solved by formulation in polymeric surfactant as P-123. The photosensitizer incorporation was found to be time dependent, exhibiting two steps: a partition at the micellar interface followed by an incorporation into the micelle core. The photodynamic efficiency of the
Quím. Nova. Publicado em: 2013
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19. Avaliação de fármacos fotossensíveis derivados da cloro alumínio ftalocianina no tratamento da progressão tumoral em modelo de matriz tridimensional mista / Evaluation of photosensitizers aluminum chloride phthalocyanine derivatives in the treatment of tumor progression in three-dimensional matrix.
Wound healing process can be favored by Low Level Laser Therapy, with the collagen and elastin matrix a dermic substitute described as an appropriate system in tissue engineering and in tridimensional skin systems. With this purpose, a study was elaborated using the system nanoemulsion of aluminium-chloride phthalocyanine (ClAlPc) as photosensitizer in skin
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/10/2012
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20. Photodynamic therapy of Pythium insidiosum inactivation in vitro and in vivo study / Terapia fotodinâmica para inativação do Pythium insidiosum - estudo in vitro e in vivo
Photodynamic Therapy (PDT) is a therapy based on the interaction of photosensitizer and light, in the presence of oxygen, to induce cellular death. Under the incidence of light, at an appropriated wavelength, these chemical compounds produce reactive oxygen species which affects the biomolecules of the target-cells. Pythiosis is a lifethreatening emerging di
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/08/2012
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21. Obtenção e caracterização de ftalocianinas com substituintes quirais com potencial aplicação em terapia fotodinâmica / Synthesis and characterization ofphthalocyanines with chiralsubstituints with potencialfor use in Photodynamic Therapy
The main objective of this project is the synthesis and characterization of new phthalocyanines with chiral substituents to improve their photophysical and photochemical properties for use as photosensitizers in Photodynamic Therapy. Three new phthalocyanines were synthesized and characterized, one with the racemic mixture of 1-(4-bromophenyl)- ethanol, and
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/02/2012
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22. Identificação de lesões de pele por detecção fotodinâmica mediada por ácido aminolevulínico / Identification of skin lesions through aminolaevulinic acidmediated photodynamic detection
No Brasil, o câncer de pele não-melanoma é o tipo de câncer mais comum, corresponde a cerca de 95% de todos os tipos de câncer de pele e 25% de todo o tipo de tumor maligno. O diagnóstico precoce permite tratar lesões logo nos primeiros estágios da doença, melhorando as condições do paciente. Assim, é de grande importância desenvolver técnicas
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 10/02/2012
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23. Estudo químico-quântico de corantes catiônico e aniônicos para aplicação em terapia fotodinâmica / Quantum-chemical study of cationic and anionic dyes applied in photodynamic therapy / Estudo químico-quântico de corantes catiônico e aniônicos para aplicação em terapia fotodinâmica / Quantum-chemical study of cationic and anionic dyes applied in photodynamic therapy
The present work studies the dyes Methylene Blue, Toluidine Blue, Eosin Y, Erytrosin B, Fluorescein and Rose Bengal using quantum-chemical calculations, aiming to propose an appropriate Density Functional Theory-based methodology and to understand the mechanisms of action of those dyes in photodynamic therapy. Structures in singlet and triplet states were op
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/04/2011
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24. Aplicação do corante da casca da berinjela em células solares fotossensibilizadas. / Application of dye from the peel of eggplant in photosensitizer in solar cells.
Despite the efficiency of conventional solar cells reach about 20%, the cost of producing electricity using photovoltaic panels about 42 cents per kWh is still much higher than the cost of power generated by hydroelectric, 8 cents per kWh. Given the high cost of producing solar panels, woke up the interest in solar cells using dyes fotoexcitáveis known as G
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2011