Photochemotherapy
Mostrando 13-20 de 20 artigos, teses e dissertações.
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13. Antimicrobial effect of photodynamic therapy on oral biofilms / Estudo da ação antimicrobiana da terapia fotodinamica sobre biofilmes orais
A terapia fotodinâmica (TFD) é um tratamento antibacteriano alternativo para as doenças causadas por biofilmes como a cárie dental. Esta tese, apresentada na forma de 3 artigos, teve por objetivos: (1) revisar a literatura enfocando o efeito da TFD em bactérias cariogênicas, (2) validar um modelo de formação de biofilme de mono-espécies de estreptoc
Publicado em: 2005
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14. Photocytotoxicity of a 5-nitrofuran-ethenyl-quinoline antiseptic (Quinifuryl) to P388 mouse leukemia cells
Quinifuryl (MW 449.52), 2-(5'-nitro-2'-furanyl)ethenyl-4-{N-[4'-(N,N-diethylamino)-1'-methylbutyl]carbamoyl} quinoline, is a water soluble representative of a family of 5-nitrofuran-ethenyl-quinoline drugs which has been shown to be highly toxic to various lines of transformed cells in the dark. In the present study, the toxicity of Quinifuryl to P388 mouse
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-12
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15. Estudo das características espectroscópicas dos corantes ciânicos com dois cromóforos na interação com DNA: efeitos da força iônica. / Spectroscopic studies of bichromophoric cyanine dyes (BCD) in their interaction with DNA: effect of ionic strength.
Cancer is a pathology responsible for a great number of deaths. The conventional methods of treatment, chemotherapy and radiotherapy, are not always efficient, and multiple side effects are intrinsic for these therapies. In early 70s appeared a new method called Photodynamic Therapy (PDT), that shows few side effects as compared with conventional thera
Publicado em: 2002
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16. Mechanisms of lymphocytotoxicity induced by extracorporeal photochemotherapy for cutaneous T cell lymphoma.
Extracorporeal photochemotherapy is an effective treatment for cutaneous T cell lymphoma but its mode of action is uncertain. The reduction in viability of patients' photoirradiated buffy coat lymphocytes was correlated with a 35% increase in DNA single-strand breaks and marked decreases in cellular ATP and NAD levels (to 58 and 34% of control, respectively)
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17. UVA/UVA1 phototherapy and PUVA photochemotherapy in connective tissue diseases and related disorders: a research based review
BioMed Central.
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18. Photochemical Inactivation of Deoxyribonucleic and Ribonucleic Acid Viruses by Chlorpromazine
Chlorpromazine, a widely used tranquilizing drug of the phenothiazine group, was found to be a very potent photochemical inactivator of both deoxyribonucleic acid and ribonucleic acid viruses in the presence of long-wave ultraviolet light (320 to 380 nm). Neither the light alone nor chlorpromazine alone caused any appreciable inactivation. The known chlorpro
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19. Intramitochondrial dyes allow selective in vitro photolysis of carcinoma cells.
Carcinoma cell mitochondria preferentially accumulate and retain certain cationic dyes to a much greater extent than most normal cells. Thus, they can potentially serve as targets for highly selective photochemotherapy. We evaluated 10 rhodamine and cyanine dyes as carcinoma-specific mitochondrial photosensitizers in vitro. The most effective, N,N'-bis(2-eth
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20. Targeted Antimicrobial Photochemotherapy
This study explores a new approach for antimicrobial therapy with light activation of targeted poly-l-lysine (pL)–chlorin e6 (ce6) conjugates. The goal was to test the hypothesis that these conjugates between pL and ce6 would efficiently target photodestruction towards gram-positive (Actinomyces viscosus) and gram-negative (Porphyromonas gingivalis) oral s
American Society for Microbiology.