Phosphoproteomics
Mostrando 1-4 de 4 artigos, teses e dissertações.
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1. Caracterização do papel das proteínas quinases C (PKCs) na proliferação e auto-renovação das células tronco embrionárias murinas / Characterization of the role of protein kinases C (PKC) in proliferation and self-renewal of murine embryonic stem cells
Células tronco embrionárias (CTE) são capazes de proliferar indefinidamente mantendo a sua pluripotência, isto é, a capacidade de se diferenciar em diversos tipos celulares perante estímulos adequados. Esse potencial tem sido intensamente estudado, de modo a permitir a utilização dessas células em terapias de reposição celular. Trabalhos anteriore
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 04/08/2011
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2. A New Approach for Quantitative Phosphoproteomic Dissection of Signaling Pathways Applied to T Cell Receptor Activation*
Reversible protein phosphorylation plays a pivotal role in the regulation of cellular signaling pathways. Current approaches in phosphoproteomics focus on analysis of the global phosphoproteome in a single cellular state or of receptor stimulation time course experiments, often with a restricted number of time points. Although these studies have provided som
The American Society for Biochemistry and Molecular Biology.
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3. Phosphoproteomics of the Arabidopsis Plasma Membrane and a New Phosphorylation Site DatabaseW⃞
Functional genomic technologies are generating vast amounts of data describing the presence of transcripts or proteins in plant cells. Together with classical genetics, these approaches broaden our understanding of the gene products required for specific responses. Looking to the future, the focus of research must shift to the dynamic aspects of biology: mol
American Society of Plant Biologists.
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4. Large-scale Proteomics Analysis of the Human Kinome
Members of the human protein kinase superfamily are the major regulatory enzymes involved in the activity control of eukaryotic signal transduction pathways. As protein kinases reside at the nodes of phosphorylation-based signal transmission, comprehensive analysis of their cellular expression and site-specific phosphorylation can provide important insights
The American Society for Biochemistry and Molecular Biology.