Phospholipids
Mostrando 25-36 de 1551 artigos, teses e dissertações.
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25. Simultaneous transfer of cholesterol, triglycerides, and phospholipids to high-density lipoprotein in aging subjects with or without coronary artery disease
OBJECTIVE: To verify whether the capacity of high-density lipoprotein (HDL) to simultaneously receive nonesterified cholesterol, triglycerides, cholesteryl esters, and phospholipids changes with aging and the presence of coronary artery disease. DESIGN: Cross-sectional study with biochemical analyses. SUBJECTS: Eleven elderly patients with coronary artery di
Clinics. Publicado em: 2011
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26. Obtenção e caracterização de frações purificadas de saponinas de chenopodium quinoa e avaliação da formação de complexos do tipo iscom : atividades biológicas das frações e dos complexos formados
Chenopodium quinoa (quinoa) seeds are a rich protein source and well-known for their high saponin content. Chemically, quinoa saponins are triterpene glycosides being phytolaccagenic, hederagenin, oleanolic and serjanic acids the most common aglycones found in seeds. Its immunoadjuvant properties have been examined and the results obtained were conflicting.
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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27. Modificações químicas do ácido hialurônico para a produção de géis reticulados e de fosfolipídios derivatizados / Chemical modification of hyaluronic acid for production of cross-linked gels and derivatized phospholipids
Neste trabalho foram estudadas as reações de modificação química do ácido hialurônico (AH) com divinilsulfona (DVS) para preparação de géis reticulados e com carbodiimidas para preparação de fosfolipídios derivatizados. A modificação com DVS envolve os grupos hidroxílicos do AH, enquanto a modificação mediada por carbodiimida envolve os gru
Publicado em: 2011
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28. Encapsulação de anfotericina B em lipossomas como sistemas de entrega modificada do fármaco para aplicação endovenosa / Encapsulation of amphotericin B into liposomes as modified delivery systems of the drug for endovenous administration
Fungal infections are among the most important causes of death among immunocompromised patients. Amphotericin B (AmB) is an antifungal polyene macrolide, representative of the group of chemotherapeutics which mechanism of action consists in change of membrane cell permeability. AmB is more damaging to fungal cells, but interacts with mammalian cell membrane
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/04/2010
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29. Melatonina, isoenzimas de glutationa S-transferases e estresse oxidante em pacu Piaractus mesopotamicus (Holmberg, 1887) / Melatonin, Glutathione S-transferases isoenzymes, and oxidative stress in pacu, Piaractus mesopotamicus (Holmberg, 1887).
Oxygen is vital for vertebrates. However, changes in the levels of dissolved oxygen in water might cause oxidative stress in fishes because the shortage of oxygen followed by reoxygenation originates reactive oxygen species (ROS) inside cells. Higher intracellular levels of ROS favor alterations of proteins, phospholipids and nucleic acid molecules, which re
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/03/2010
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30. Thermodynamics of molecular recognitions between antineoplastic drug taxol and phosphatidylcholine
The aim of this study was to study the basic features of Taxol recognition with phospholipids by applying the thermodynamic and spectroscopic measurements. The obtained information could be used further for deductions on its precise cellular and pharmacological mechanisms of action, on improvements of its solubility properties by phospholipids, as well as fo
Brazilian Archives of Biology and Technology. Publicado em: 2010-12
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31. Expression of mdr isoforms in mice during estrous cycle and under hormone stimulation
The multidrug resistance (MDR) phenotype is associated with the expression of P-glycoprotein (Pgp), coded by the multigenic mdr family. Mice present the isoforms mdr1 and mdr3, which are responsible for multidrug resistance, and mdr2, that is involved in the transport of phospholipids. mdr1 expression has more recently been associated also with the secretion
Publicado em: 2010
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32. Chronic postnatal administration of methylmalonic acid provokes a decrease of myelin content and ganglioside N-acetylneuramic acid concentration in cerebrum of young rats
Levels of methylmalonic acid (MMA) comparable to those of human methylmalonic acidemia were achieved in blood (2-2.5 mmol/l) and brain (1.35 µmol/g) of rats by administering buffered MMA, pH 7.4, subcutaneously twice a day from the 5th to the 28th day of life. MMA doses ranged from 0.76 to 1.67 µmol/g as a function of animal age. Control rats were treated
Publicado em: 2010
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33. Desenvolvimento de metodologia para funcionalizar superfícies de ouro com biomoléculas. Construção de biosensor para detecção de citocromo c. / Development of methodology to functionalize gold surfaces with biomolecules. Construction of biosensor for detection of cytochrome c
Neste trabalho estão apresentadas novas estratégias para funcionalizar superfícies de ouro baseadas na sustentação de bicamadas lipídicas em superfícies de sensores de imagem por Ressonância de Plasmons de Superfície (SPRi) e a construção de um biosensor para detecção de citocromo c. SPRi é uma técnica ótica de gravimetria em tempo real. Por
Publicado em: 2010
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34. Efeito de características estruturais da quitosana sobre sua interação com filmes de Langmuir como modelo de biomembrana / Effects from the structural characteristics of chitosan on its interaction in Langmuir films as biomembrane models.
Chitosans are polysaccharides used in medicine, pharmacy, dentistry and in the inhibition of microorganisms growth (eg. as bactericidal agent). In these applications their action should depend on the interaction with cell membranes, which is difficult to verify because isolating a membrane is not easy. An alternative is to investigate the interaction with me
Publicado em: 2010
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35. Na,K-ATPase reconstituída em lipossomos de fosfolipídios e colesterol: caracterização biofísica e bioquímica / Na,K-ATPase reconstituted into phospholipids and cholesterol liposomes: biochemical and biophysical characterization.
A Na,K-ATPase é uma proteína integral que utiliza a energia derivada da hidrólise do ATP para transportar íons Na+ e K+ através da membrana contra seus gradientes eletroquímicos. É composta por três subunidades, denominadas alfa, beta e gama. Alguns autores defendem que o protômero (alfa-beta) seja a unidade estrutural e funcional da enzima, porém
Publicado em: 2010
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36. INFLUENCE DIFFERENT FATTY ACID OF THE DIET ON AN ANIMAL MODEL OF MANIA INDUCED BY AMPHETAMINE IN RATS / INFLUÊNCIA DOS DIFERENTES ÁCIDOS GRAXOS DA DIETA SOBRE UM MODELO ANIMAL DE MANIA INDUZIDO POR ANFETAMINA EM RATOS
Fatty acids (FA) are constituent important of the neuronal phospholipids membranes and they carry out important functions in the development and function of the brain During the last decades changes were observed in the feeding habits of western countries, with an increase of the trans FA and omega-6 (n-6) and detriment of omega-3 fatty acids (n-3) consumpti
Publicado em: 2010