Phentolamine
Mostrando 1-12 de 254 artigos, teses e dissertações.
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1. The vascular and neurogenic factors associated with erectile dysfunction in patients after pelvic fractures
ABSTRACT Erectile dysfunction (ED) is a common complication of pelvic fractures. To identify the vascular and neurogenic factors associated with ED, 120 patients admitted with ED after traumatic pelvic fracture between January 2009 and June 2013 were enrolled in this study. All patients answered the International Index of Erectile Function (IIEF-5) questionn
Int. braz j urol.. Publicado em: 2015-10
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2. Modulatory effects of taurine on jejunal contractility
Taurine (2-aminoethanesulfonic acid) is widely distributed in animal tissues and has diverse pharmacological effects. However, the role of taurine in modulating smooth muscle contractility is still controversial. We propose that taurine (5-80 mM) can exert bidirectional modulation on the contractility of isolated rat jejunal segments. Different low and high
Braz J Med Biol Res. Publicado em: 14/10/2014
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3. Vasoconstrictor effect of Africanized honeybee (Apis mellifera L.) venom on rat aorta
Background : Apis mellifera stings are a problem for public health worldwide, particularly in Latin America due to the aggressiveness of its Africanized honeybees. Massive poisoning by A. mellifera venom (AmV) affects mainly the cardiovascular system, and several works have described its actions on heart muscle. Nevertheless, no work on the pharmacological
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 25/09/2013
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4. Molecular and phenotypic characterization of Acinetobacter calcoaceticus-Acinetobacter baumannii isolates / Caracterização molecular e fenotípica de amostras bacterianas pertencentes ao complexo Acinetobacter calcoaceticus-Acinetobacter baumannii
The genus Acinetobacter has emerged as one of the most troublesome pathogens for health care institutions globally. Its clinical significance, especially over the last 15 years, has been driven by its remarkable ability to up regulate or acquire resistance determinants, making it one of the organisms threatening the current antibiotic era. A. baumannii, A. 3
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/08/2011
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5. Renal- and calcium-dependent vascular effects of Polybia paulista wasp venom
In the present study, the effects of Polybia paulista venom (PPV) on renal and vascular tissues were investigated. Isolated kidneys perfused with PPV (1 and 3 μg/mL) had increased perfusion pressure, renal vascular resistance, urinary flow, and glomerular filtration rate; and reduced sodium tubular transport. Histological evaluation demonstrated deposits of
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2011
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6. Effect of cyproterone acetate on alpha1-adrenoceptor subtypes in rat vas deferens
Gonadal hormones regulate the expression of alpha1-adrenoceptor subtypes in several tissues. The present study was carried out to determine whether or not cyproterone acetate, an anti-androgenic agent, regulates the alpha1-adrenoceptor subtypes that mediate contractions of the rat vas deferens in response to noradrenaline. The actions of subtype selective al
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-11
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7. Fentolamina: aspectos farmacocinéticos e farmacodinâmica no corpo carvenoso humano / Phentolamine: pharmacokinetic aspects and pharmacodynamics in human corpus cavernosum. In vivo and in vitro study
Disfunção erétil (DE) é definida como uma inabilidade para conseguir e manter uma ereção para satisfação sexual. A fentolamina um antagonista a-adrenérgico tem sido usado para tratar DE desde 1994, principalmente em combinação com outros agentes vasoativos. Mais recentemente uma formulação oral mesilato de fentolamina foi desenvolvida para a doe
Publicado em: 2003
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8. Estudo do efeito da dobutamina (Dobutrex) R e da radiação laser sobre a ação hidrosmotica da vasopressina em bexiga de sapo "in vitro"
In the present work the effects of several pharmacological agents in special Dobutamine and a physical agent-Laser radiation - on the events that follow the interaction of Vasopressin with membrane receptors related to syn¬thesis and inactivation of cyclic-AMP in the toad bladder, are described and characterized. Water flow across the membrane was measured
Publicado em: 1991
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9. Alpha 1- and alpha 2-adrenoreceptor actions of phentolamine and prazosin on breathing movements in fetal sheep in utero.
1. We studied the effects of systemic administration of the alpha 1- and alpha 2-adrenoreceptor antagonist phentolamine and the selective alpha 1-adrenoreceptor antagonist prazosin on fetal breathing movements (FBM) and electrocortical activity (ECoG) in fetal sheep. In one group of fetuses (group I; n = 7) the effects of phentolamine were measured during no
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10. Electrophysiological properties of phentolamine in man.
The effects of phentolamine, 0-3 mg/min given intravenously for 15 minutes, on His bundle electrograms were studied in 11 patients with heart disease. Recordings were made at varied heart rates, using atrial pacing. Phentolamine significantly reduced the AH interval in every patient but it had no effect on the HV interval. Functional and effective refractory
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11. Phentolamine block of KATP channels is mediated by Kir6.2
The ATP-sensitive K+-channel (KATP channel) plays a key role in insulin secretion from pancreatic β cells. It is closed both by glucose metabolism and the sulfonylurea drugs that are used in the treatment of noninsulin-dependent diabetes mellitus, thereby initiating a membrane depolarization that activates voltage-dependent Ca2+ entry and insulin release. T
The National Academy of Sciences of the USA.
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12. New detection of brain dopamine receptors with (3H)dihydroergocryptine.
Because dihydroergocryptine (DHE) and closely related ergots are dopamine-mimetic agonists, we tested [3H]DHE as a possible ligand for [3H]dopamine receptors in the calf caudate. In order to avoid [3H]DHE from tagging alpha-adrenergic receptors, an excess of 500 nM phentolamine was used to block these sites, permitting the dopamine receptors to be measured s