Pharmaceutical Preparations
Mostrando 1-12 de 92 artigos, teses e dissertações.
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1. Toxicological effects of ciprofloxacin and chlorhexidine on growth and chlorophyll a synthesis of freshwater cyanobacteria
Cyanobacteria are phytoplanktonic microorganisms that are susceptible to the deleterious effects of pharmaceutical residues in the aquatic environment, which poses a challenge to the environment exposed to diverse pharmaceutical products and their potential effects. The objective of this study was to evaluate the effects of the antibiotic substances ciproflo
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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2. Construction and Evaluation of a Graphene Oxide Functionalized Aminopropyltriethoxy Silane Surface Molecularly Imprinted Polymer Potentiometric Sensor for Dipyridamole Detection in Urine and Pharmaceutical Samples
A dipyridamole (DIP) based surface molecularly imprinted polymer (MIP) was synthesized and applied as a sensing agent in a sensing layer of a new modified potentiometric carbon paste electrode (CPE). The potentiometric modified CPEs (GO@SiO2-NH2-MIP/MWCNTs/CPE, where GO is graphene oxide and MWCNTs is multi-walled carbon nanotubes) showed an improved perform
J. Braz. Chem. Soc.. Publicado em: 16/09/2019
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3. A Novel Thermal Infrared Enthalpimetric Method for Fast, High-Throughput Determination of the Content Uniformity of Captopril Tablets
Content uniformity (CU) is a parameter used to ensure the uniformity of the amount of active substances in pharmaceutical preparations. It is often evaluated in the quality control of pharmaceutical dosage forms, and a novel method was proposed for CU determination using thermal infrared enthalpimetry (TIE). Captopril tablets were dissolved in 24-well microp
J. Braz. Chem. Soc.. Publicado em: 08/04/2019
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4. Laboratory evidence for the hematopoietic potential of Beta vulgaris leaf and stalk extract in a phenylhydrazine model of anemia
This study was designed to provide laboratory evidence supporting the hematopoietic effect of Beta vulgaris (beet) leaf aqueous extract in phenylhydrazine-induced anemia model in albino rats. Extraction of the leaves/stalks was done by maceration in 30% hydro-ethanol for 48 h. An intraperitoneal injection of 20 mg/kg phenylhydrazine was applied for two conse
Braz J Med Biol Res. Publicado em: 11/10/2018
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5. Simultaneous determination of abamectin homologs H 2 B 1a and H 2 B 1b in gel formulation by high performance liquid chromatography
ABSTRACT Abamectin is a drug with antiparasitic properties used in several pharmaceutical formulations. The objective of this research was to develop and validate a high performance liquid chromatographic (HPLC) method for quantification of the two abamectin homologs (H2B1a and H2B1b) in gel formulation. This HPLC method was validated using a LichroCart(r) 1
Braz. J. Pharm. Sci.. Publicado em: 2016-09
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6. Simultaneous determination of amoxicillin and clavulanic acid in pharmaceutical preparations by capillary zone electrophoresis
RESUMO O ácido clavulânico acentua o espectro antibacteriano de amoxicilina, tornando a maioria dos isolados produtores de β-lactamase sensíveis ao fármaco. Desenvolveu-se um método rápido, simples e eficiente de electroforese capilar (EC) para a determinação simultânea de amoxicilina e de ácido clavulânico a partir de misturas complexas. Usando
Braz. J. Pharm. Sci.. Publicado em: 2016-06
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7. Development and Validation of a New Spectrophotometric Method for the Determination of Cephalexin Monohydrate in Pure Form and Pharmaceutical Formulations
A simple, fast, sensitive and accurate spectrophotometric method has been developed for the quantitative determination of cephalexin monohydrate in dosage form and in commercial formulations. The method involves the addition of CeIV to cephalexin in acidic medium, followed by the determination of residual CeIV by reacting with a fixed amount of methyl orange
J. Braz. Chem. Soc.. Publicado em: 2016-05
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8. Development and application of a portable instrument for drugs analysis in pharmaceutical preparations
Este artigo descreve o desenvolvimento e a aplicação de um dispositivo portátil, simples e barato para a determinação colorimétrica quantitativa de fármacos em formulações farmacêuticas. O sensor é um resistor detector de luz (RDL) colocado numa célula de PTFE e acoplado a um multímetro de baixo custo. Os estudos quantitativos foram realizados u
Braz. J. Pharm. Sci.. Publicado em: 2015-09
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9. In vitro photoprotective effects of Marcetia taxifolia ethanolic extract and its potential for sunscreen formulations
AbstractThe species Marcetia taxifolia (A. St.-Hil.) DC., Melastomataceae, which is endemic of the rupestrian fields of northeastern Brazil, contains a significant amount of flavonoids. In this work, the potential of the ethanolic extract of M. taxifolia as the active principle in a sunscreen photoprotection (UV-A and UV-B) formulation was investigated. The
Rev. bras. farmacogn.. Publicado em: 2015-08
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10. A simple and sensitive method for determination of Norfloxacin in pharmaceutical preparations
Propos-se, por essa abordagem, novo método voltamétrico, com alta sensibilidade e faixa linear de detecção mais ampla, para a determinação de norfloxacino. O sensor voltamétrico utilizado foi fabricado simplismente por cobertura de camada de óxido de grafeno (GO) e filme de Nafion em eletrodo de cabrono vítreo. A vantagem do método proposto foi
Braz. J. Pharm. Sci.. Publicado em: 2015-06
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11. Differential pulse voltammetric determination of diclofenac in pharmaceutical preparations and human serum
Este artigo descreve um método de voltametria de pulso diferencial (VPD) para a determinação de diclofenaco em preparações farmacêuticas e em soro humano. O método proposto foi baseado em eletroxidação de diclofenaco no eléctrodo de platina em solução 0,1 M TBAClO4/acetonitrila. Dois picos de oxidação bem definidos foram observado
Braz. J. Pharm. Sci.. Publicado em: 2015-06
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12. Interferência do tratamento medicamentoso imediato e tardio na doença de Parkinson no gerenciamento da disfagia
A Doença de Parkinson apresenta grande incidência na população idosa, gerando comprometimento motor progressivo, que afeta várias funções, dentre as quais se destaca a deglutição. Esse trabalho teve como objetivo relacionar a disfagia na Doença de Parkinson aos efeitos imediatos e/ou tardios do tratamento medicamentoso, que de forma direta ou indir
Rev. CEFAC. Publicado em: 2014-04