Peromyscus
Mostrando 37-48 de 91 artigos, teses e dissertações.
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37. Experimental infection model for Sin Nombre hantavirus in the deer mouse (Peromyscus maniculatus)
The relationship between hantaviruses and their reservoir hosts is not well understood. We successfully passaged a mouse-adapted strain of Sin Nombre virus from deer mice (Peromyscus maniculatus) by i.m. inoculation of 4- to 6-wk-old deer mouse pups. After inoculation with 5 ID50, antibodies to the nucleocapsid (N) antigen first became detectable at 14 d whe
The National Academy of Sciences.
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38. New infectious spirochete isolated from short-tailed shrews and white-footed mice.
A spirochete with two periplasmic flagella was isolated from the blood or tissues of spleens and kidneys from short-tailed shrews (Blarina brevicauda) and white-footed mice (Peromyscus leucopus) in Connecticut and Minnesota. After inoculation, the shrew-mouse spirochete infected Swiss mice and Syrian hamsters. This spirochete is morphologically and serologic
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39. Carbonic Anhydrase Polymorphism in a New Jersey Population of the White-Footed Mouse PEROMYSCUS LEUCOPUS
Two electrophoretic forms of erythrocytic carbonic anhydrase were found to be controlled by one autosomal locus with two codominant alleles, CAf and CA8. The gene frequencies for the CAf and CA8 alleles were found to be.15 and.85, respectively, in a sample of 53 mice from Middlesex County, New Jersey. The observed genotypic frequencies indicated that the pop
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40. Sin Nombre Virus Pathogenesis in Peromyscus maniculatus
Sin Nombre virus (SNV), a member of the Hantavirus genus, causes acute viral pneumonia in humans and is thought to persistently infect mice. The deer mouse, Peromyscus maniculatus, has been identified as the primary reservoir host for SNV. To understand SNV infection of P. maniculatus, we examined wild deer mice for localization of viral antigens and nucleic
American Society for Microbiology.
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41. The Use of Restriction Endonucleases to Measure Mitochondrial DNA Sequence Relatedness in Natural Populations. I. Population Structure and Evolution in the Genus Peromyscus
In this study we introduce to natural population analysis a molecular technique that involves the use of restriction endonucleases to compare mitochondrial DNA (mtDNA) sequences. We have examined the fragment patterns produced by six restriction endonucleases acting upon mtDNA isolated from 23 samples of three species of the rodent Peromyscus. Our observatio
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42. Prevalence of Borrelia burgdorferi and Babesia microti in mice on islands inhabited by white-tailed deer.
Borrelia burgdorferi and Babesia microti were isolated from 35 of 51 white-footed mice (Peromyscus leucopus) and meadow voles (Microtus pennsylvanicus) captured on two Narragansett Bay, R.I., islands inhabited by deer, the principal host for the adult stages of the vector tick, Ixodes dammini. Immature ticks parasitized mice from both islands. From 105 mice
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43. Role of Maternal Antibody in Natural Infection of Peromyscus maniculatus with Sin Nombre Virus
Data from naturally infected deer mice (Peromyscus maniculatus) were used to investigate vertical transmission of Sin Nombre virus (SNV) and SNV-specific antibody. The antibody prevalence in juvenile mice (14 g or less) was inversely proportional to the mass of the animal, with juvenile deer mice weighing less than 11 g most likely to be antibody positive (2
American Society for Microbiology.
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44. Comparison of polymerase chain reaction and culture for detection of Borrelia burgdorferi in naturally infected Peromyscus leucopus and experimentally infected C.B-17 scid/scid mice.
Culture and the polymerase chain reaction (PCR) were compared for detection of Borrelia burgdorferi infection in wild-caught Peromyscus leucopus and experimentally inoculated C.B-17 scid/scid (severe combined immunodeficient) mice. PCR targeted highly conserved regions of the ospA gene and could detect one to five cultured organisms and 10 to 50 copies of mo
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45. Spontaneous "regression" of enhanced immune function in a photoperiodic rodent Peromyscus maniculatus.
Short days inhibit reproduction and enhance immune function in deer mice (Peromyscus maniculatus). Their reproductive inhibition is sustained by an endogenous timing mechanism: after ca. 20 weeks in short days, reproductive photorefractoriness develops, followed by spontaneous recrudescence of the reproductive system. It is unknown whether analogous seasonal
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46. Normal testicular structure and reproductive function in deermice lacking retinol and alcohol dehydrogenase activity.
It was found that a strain of deermice (Peromyscus maniculatus), which genetically lacks liver alcohol dehydrogenase activity also displays no such activity in the testis and is devoid of the enzyme activity that converts retinol to retinal, both in liver and in the testis; nevertheless, these animals exhibit normal reproduction and testicular histology. The
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47. Serologic Evidence of Infection with Ehrlichia spp. in Wild Rodents (Muridae: Sigmodontinae) in the United States
Rodent (Muridae: Sigmodontinae) blood and sera collected from 14 states were tested for seroreactivity to a cultured isolate of the human granulocytic ehrlichiosis (HGE) agent by using an indirect immunofluorescence assay. Of the 1,240 samples tested, 136 (11%) were found to be reactive at titers of ≥32. Rodents with HGE agent-specific antibodies were foun
American Society for Microbiology.
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48. Infection with Agents of Human Granulocytic Ehrlichiosis, Lyme Disease, and Babesiosis in Wild White-Footed Mice (Peromyscus leucopus) in Connecticut
White-footed mice, Peromyscus leucopus, were captured in southern Connecticut during 1997 and 1998 to determine the prevalence of infections caused by granulocytic Ehrlichia sp., Borrelia burgdorferi, and Babesia microti. Of the 50 mice captured and recaptured, 25 of 47 (53.2%) and 23 of 48 (47.9%) contained antibodies to the BDS or NCH-1 Ehrlichia strains,
American Society for Microbiology.