Perfused Kidney
Mostrando 1-12 de 126 artigos, teses e dissertações.
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1. The role of fetal-maternal microchimerism as a natural-born healer in integrity improvement of maternal damaged kidney
ABSTRACT Purpose: To identify the fetal stem cell (FSC) response to maternal renal injury with emphasis on renal integrity improvement and Y chromosome detection in damaged maternal kidney. Materials and Methods: Eight non-green fluorescent protein (GFP) transgenic Sprague-Dawley rats were mated with GFP-positive transgenic male rats. Renal damage was indu
Int. braz j urol.. Publicado em: 2018-06
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2. ESTUDO DOS EFEITOSDA BRADICININA SOBRE A FUNÇÃO RENAL DE RATOS / STUDY OF EFEITOSDA bradykinin ON RENAL FUNCTION IN RATS
O sistema calicreína-cinina corresponde a uma cascata metabólica endógena, que resulta na liberação de cininas vasoativas, das quais a mais conhecida é a bradicinina (BK). Esta cinina está envolvida tanto na regulação da função renal, como também da pressão arterial, estimulando efeito hipotensor, natriurético e elucidados. O presente trabalho
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/04/2011
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3. Renal- and calcium-dependent vascular effects of Polybia paulista wasp venom
In the present study, the effects of Polybia paulista venom (PPV) on renal and vascular tissues were investigated. Isolated kidneys perfused with PPV (1 and 3 μg/mL) had increased perfusion pressure, renal vascular resistance, urinary flow, and glomerular filtration rate; and reduced sodium tubular transport. Histological evaluation demonstrated deposits of
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2011
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4. Renal and vascular effects of Crotalus durissus cumanensis venom and its crotoxin fraction
In this study, we evaluated the actions of Crotalus durissus cumanensis venom (CDCmV), and its crotoxin (Crtx) fraction, on renal and vascular functions in Wistar rats. In isolated perfused kidneys, CDCmV (10 µg/mL) significantly increased the perfusion pressure (PP) from 110.7 ± 2.4 to 125.3 ± 2.8 mmHg after 30 minutes. This effect was accompanied by an
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2011
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5. Efeitos inibitÃrios da sertralina no sistema urinÃrio de ratos. / Inhibitory effects of sertraline on rat urinary system.
Sertraline, a drug belonging to the family of selective serotonin reuptake inhibitors, is used in antidepressant therapy, and has good tolerance with low incidence of side effects. Here we have characterized the pharmacological effects of sertraline on the pattern of voiding anesthetized rats, on the renal functional parameters of isolated rat kidney and on
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/11/2010
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6. AvaliaÃÃo dos efeitos renais da fraÃÃo L-aminoÃcido Oxidase isolada do veneno da serpente Bothrops marajoensis. / Assessment of renal effects of L-amino acid oxidase fraction isolated from snake Bothrops marajoensis venom.
There are about 3.000 species of snakes worldwide, but only 10 to 14% are venomous. Among South American countries, Brazil is the one with the largest number of accidents, with approximately 20.000 snakebites each year. According to the Department of Health of Brazil, the genus Bothrops are the main involved in snakebites in the country. Acute renal failure
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/08/2010
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7. Estudo dos efeitos renais do veneno da serpente Lachesis muta muta. / Study of renal effects of Lachesis muta muta venom.
The accident caused by the snake Lachesis muta muta is serious and its venom is responsible for many systemic changes, such as hypotension. In this work, the renal effects of the total venom of this snake in the renal perfusion system and in cultured renal tubular cells of the type MDCK (Madin-Darby Canine Kidney) are investigated. Isolated kidneys from Wist
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/01/2010
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8. ESTUDO DOS EFEITOS RENAIS E VASCULARES DO VENENO DA SERPENTE Crotalus durissus cumanensis E CROTOXINA / RENAL AND VASCULAR EFFECTS FROM Crotalus durissus cumanensis VENOM AND CROTOXIN
Ophidian accidents involving species of the genus Crotalus, are usually serious and frequently fatal due to the frequency of acute renal failure. Unfortunately, there have been few studies of the toxinologic effects of Crotalus durissus cumanensis venom. The renal effects of the venom used in this study were observed by perfusion of isolated kidneys. Infusio
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 07/07/2009
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9. Estudo dos efeitos da alta ingestÃo de cloreto de sÃdio por via oral sobre o metabolismo diÃrio e funÃÃo renal de ratos. / Study of effects on the daily metabolism and the renal function of rats under high oral ingestion of sodium chloride.
Guanylin (GN), uroguanylin (UGN), and the bacterial heat-stable enterotoxin (ST) peptides comprise a new family of cyclic guanosine 3â-5â monophosphate (cGMP)-regulating agonist. Ingestion of a salt meal induces secretion of GN and UGN into the intestinal lumen, where they inhibit Na+ absorption and induces Cl-, HCO3- , and water secretion. Simultaneously,
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/01/2009
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10. Antivenom action on renal effects induced by Thalassophryne nattereri venom
Thalassophryne nattereri (niquim) is a venomous fish responsible for numerous accidents involving fishermen in northern and northeastern Brazil. The aim of the present investigation was to evaluate the action of antivenom on renal effects caused by Thalassophryne nattereri venom. Isolated kidneys of Wistar rats were perfused with a previously dialyzed Krebs-
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2009
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11. A renal study of the interactions between uroguanilia, urodilatia and predry bradiciiana of the chokes of the guanilato ciclase isatin and ODQ / Um estudo renal das interaÃÃes entre uroguanilia, urodilatina e bradicinina na presenÃa dos bloqueadores da guanilato ciclase isatin e ODQ
IntroduÃÃo: Guanilinas, peptÃdeos natriurÃticos (ANP e urodilatina) e bradicinina estÃo implicados na fisiopatologia, com potencial terapÃutico, do metabolismo do sal e da hipertensÃo. Objetivo: Estudar o mecanismo de aÃÃo e possÃveis interaÃÃes destes peptÃdeos, pelo emprego de inibidores da guanilato ciclase isatina e ODQ. MÃtodo: Foram reali
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/04/2008
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12. Biological effects induced by Tityus serrulatus crude venom and its toxins TsTx-V, gamma toxin and natriuretic peptide / Efeitos biolÃgicos induzidos pelo veneno total de Tityus serrulatus e suas fraÃÃes TsTx-V, toxina gama e peptÃdeo natriurÃtico
The venom of Tityus serrulatus has a mixture of toxic and non toxic peptides presenting diverse systemic and local effects. The aim of this work was to investigate the cardiovascular and renal effects promoted by the crude venom of the scorpion Tityus serrulatus and its isolated components such as Tityus serrulatus toxin V (TsTx-V), Gamma Toxin and the newly
Publicado em: 2008