Particle Systems
Mostrando 13-24 de 319 artigos, teses e dissertações.
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13. Synthesis of ordered mesoporous silica MCM-41 with controlled morphology for potential application in controlled drug delivery systems
Resumo O MCM-41 é uma das cerâmicas mesoporosas mais estudadas para sistemas de liberação controlada de fármacos. Sua elevada área superficial específica e mesoporosidade permitem alta capacidade de adsorção. Apesar dos inúmeros trabalhos publicados na área biomédica, até o presente momento não há relatos de aplicações comerciais do MCM-41.
Cerâmica. Publicado em: 06/06/2019
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14. Preparation and characterization of cefuroxime axetil solid dispersions using poloxamer 188
The main objective of the present work was to enhance the solubility and dissolution rate of poorly water-soluble drug cefuroxime axetil (CA) by formulating it into solid dispersions (SDs) with water soluble carrier poloxamer 188. Different methods were employed to prepare the dispersion, such as: Solvent method (SM), Kneading method (KM), Melt evaporation m
Braz. J. Pharm. Sci.. Publicado em: 08/04/2019
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15. Insights on Structuration of Peroxotungstic Acid in Aqueous Media
Recent studies on tungsten oxide preparation are mainly motivated by its applications in smart windows, energy harvesting and, recently, in cancer therapy. Peroxotungstic acid (PTA) is an important precursor to obtain tungsten oxide in an environmentally-friendly way, through the colloidal synthesis in aqueous media. Despite giving chemically pure products,
J. Braz. Chem. Soc.. Publicado em: 2019-04
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16. Velocidade limite c
Resumo Neste artigo, é proposta uma nova maneira de ensinar estudantes de graduação que a velocidade de luz c é um limite físico para corpos materiais. Dois diferentes 'gedankenexperimente', conceitualmente equivalentes, baseados em princípios de eletrodinâmica básica são propostos e discutidos, chegando à mesma conclusão de que se um corpo materi
Rev. Bras. Ensino Fís.. Publicado em: 14/03/2019
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17. Physicochemical Characterizations and Antioxidant Property of Copaiba Oil Loaded into SNEDDS Systems
Self-nanoemulsion drug delivery systems (SNEDDS) represent a potential carrier to improve solubility and bioavailability of health care products. In this sense, copaiba oil (CO) loaded on cosurfactant-free SNEDDS formulations (CO-SNEDDS) were obtained by using phase diagram performed on different concentrations of constituents (oil, surfactant and water). Th
J. Braz. Chem. Soc.. Publicado em: 2019-02
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18. Process Evaluation of Sugar-Based Polymeric Colloidal Nanocarrier Formation
Abstract Several studies have demonstrated that sugar-based nanocarriers are recommended to develop drug delivery systems since they are biocompatible and biodegradable and might improve the therapeutic index of currently used drugs by reducing their toxicity and enhancing their bioavailability. Therewith, this work studied the processing conditions to forma
Mat. Res.. Publicado em: 31/01/2019
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19. Catalytic Ozonation of Melanoidin in Aqueous Solution over CoFe2O4 Catalyst
In this work, cobalt ferrite (CoFe2O4) was synthesized by solvothermal route for application as a catalyst in the ozonation reaction for the decolorization and mineralization of melanoidin from aqueous solution. The structural properties of CoFe2O4 sample were investigated by X-ray diffraction (XRD), nitrogen adsorption-desorption isotherms, Fourier-transfor
Mat. Res.. Publicado em: 08/11/2018
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20. Manufacturing of Cu-Sn foams through SDP
ABSTRACT This work reports the processing of bronze foams manufactured by using the powder metallurgy method known as Sintering Dissolution Process. During the sintering step, a device with controlled atmosphere separated from the heating furnace was employed to avoid the quick oxidation of metal particles. The device allows to control its internal atmospher
Matéria (Rio J.). Publicado em: 19/07/2018
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21. Frozen-to-jamming-to-fluid Transition of Weakly Sheared Granular Systems by Low-frequency Mechanical Spectroscopy
Granular matter usually displays frozen, jamming and fluidized states when submitted to an external vibration with increasing intensity. The dissipation properties of granular systems with three different millimeter-size glass grains (0.1, 0.5 and 1.9 mm) have been investigated by a modified low-frequency inverted torsion pendulum under a shear strain and an
Mat. Res.. Publicado em: 10/07/2018
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22. Preparation and characterization of non-viral gene delivery systems with pEGFP-C1 Plasmid DNA
ABSTRACT In recent years, non-viral delivery systems for plasmid DNA have become particularly important. They can overcome the disadvantages of viral systems such as insertional mutagenesis and unpredicted immunogenicity. Some additional advantages of non-viral gene delivery systems are; good stability, low cost, targetability, delivery of a high amount of g
Braz. J. Pharm. Sci.. Publicado em: 07/06/2018
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23. Potential doxorubicin delivery system based on magnetic gelatin microspheres crosslinked with sugars
Abstract The preparation and characterization of magnetic microspheres based on gelatin for use in drug delivery systems are reported. Sugars were employed as crosslinking agents and type A gelatin and type B gelatin were compared to prepare microspheres by water-in-oil emulsion. The influence of gelatin and sucrose concentration, temperature and stirring s
Polímeros. Publicado em: 21/05/2018
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24. Physical characterization of multiparticulate systems
ABSTRACT The search for new pharmaceutical dosage forms and different drug delivery systems already used in therapeutics is a global trend, serving as an opportunity to expand the portfolio for the pharmaceutical industry. In this context, multiparticulate systems, such as pellets, granules, and minitablets, represent an attractive alternative, given the ran
Braz. J. Pharm. Sci.. Publicado em: 07/05/2018