Parawixia Bistriata
Mostrando 1-5 de 5 artigos, teses e dissertações.
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1. Neuroprotective properties of RT10, a fraction isolated from Parawixia bistriata spider venom, against excitotoxicity injury in neuron-glia cultures
Abstract Background: L-Glutamate (L-Glu), the major excitatory neurotransmitter in the mammalian Central Nervous System (CNS), is essential to cognitive functions. However, when L-Glu is accumulated in large concentrations at the synaptic cleft, it can induce excitotoxicity that results in secondary damage implicated in many neurological disorders. Current
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 16/05/2019
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2. Avaliação da atividade neuroprotetora da Parawixina 11 isolada da peçonha da aranha Parawixia bistriata (Araneae, Araneidae), em ratos Wistar submetidos a um modelo de glaucoma agudo / Neuroprotective activity analysis of Parawixin 11, isolated from Parawixia bistriata (Araneae, Araneidae) spider venom, in Wistar rats submitted to an model of acute glaucoma
Glaucoma is defined as a typical optic neuropathy characterized by ganglion cells loss and consequent optic nerve damage, resulting in a gradual reduction of the visual field and eventual blindness. In regard to compounds present in spider venoms, they represent an interesting source of bioactive molecules and the study about the possible neuroprotective eff
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/04/2012
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3. Expressão e purificação da proteína MaSp 2 isolada da glândula produtora de teia da aranha parawixia bistriata
Spider silks are constituted essentially of proteins, secreted by specialized glands found in different groups of arthropods. All spider species can produce silks, biopolymers synthesized by abdominal glands and polymerized through a series of spinnerets. Spiders may present seven different types of glands, each producing different fibers. These differences
Publicado em: 2008
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4. Efeitos biológicos da peçonha da aranha Parawixia bistriata em ratos: isolamento e caracterização química parcial de uma neurotoxina pró-convulsivante / Biological effects of the Parawixia bistriata spider venon in rats: isolation and partially chemical characterization of a convulsant neurotoxin.
Arthropod venoms are rich sources of neurotoxins, molecular tools with selective and specific actions over the mamalian central nervous system with great clinical and scientific importance. Previous work of our laboratory showed that the spider venom of Parawixia bistriata, when injected by intracerebroventricular (i.c.v.) route, induced convulsive seizures
Publicado em: 2003
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5. Neuroethological analysis, convulsant and anticonvulsant in vivo activity of the Parawixia bistriata spider venom in rats: central and peripheric injections. / Análise neuroetológica e estudo da atividade pró-convulsivante e anticonvulsivante in vivo da peçonha bruta da aranha Parawixia bistriata em ratos: injeção central e periférica.
Durante a evolução, alguns animais desenvolveram toxinas que são capazes tanto de paralisar quanto de matar suas presas, através de ação seletiva sobre receptores ou canais iônicos. As acilpoliaminas, por exemplo, são componentes não-proteicos antagonistas dos receptores glutamatérgicos acoplados a canais iönicos, que mostraram-se anticonvulsivant
Publicado em: 1999