Paradoxical Sleep Deprivation
Mostrando 1-12 de 12 artigos, teses e dissertações.
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1. Behavioral, affective, and cognitive alterations induced by individual and combined environmental stressors in rats
Objective: To evaluate whether exposing rats to individual or combined environmental stressors triggers endophenotypes related to mood and anxiety disorders, and whether this effect depends on the nature of the behavior (i.e., innate or learned). Methods: We conducted a three-phase experimental protocol. In phase I (baseline), animals subjected to mixed sc
Braz. J. Psychiatry. Publicado em: 14/03/2019
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2. Influence of food restriction on lipid profile and spontaneous glucose levels in male rats subjected to paradoxical sleep deprivation
OBJECTIVES: The purpose of this study was to determine the paired consequences of food restriction and paradoxical sleep deprivation on lipid profile and spontaneous glucose levels in male rats. METHOD: Food restriction began at weaning, with 6 g of food being provided per day, which was subsequently increased by 1 g per week until reaching 15 g per day by t
Clinics. Publicado em: 2012
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3. Paradoxical sleep deprivation is related to muscle atrophy and damages muscle recovery / A privação de sono paradoxal em ratos está associada a atrofia muscular e déficit na recuperação muscular
Introduction: Paradoxical sleep deprivation (PSD) in rats is able to induce reductions in body mass and body fat, due to increased secretion of pituitary-adrenal axis hormones. Considering that PSD is also associated with a decrease in anabolic hormones, skeletal muscle can also be strongly influenced, causing atrophy damaging its recovery after a lesion. Ob
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/07/2011
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4. Efeitos da privação de sono paradoxal na nocicepção e ansiedade em ratos / Effects of paradoxical sleep deprivation in rats on nociception and anxiety
Paradoxical sleep deprivation (PSD) causes several neurochemical and behavioral changes related to alterations in neurotransmitters systems. Increased responses to nociceptive stimuli have been reported in animals deprived of this phase of sleep. The commonly used methods of PSD have been linked to the generation of anxiety in animals, and hyperalgesia could
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/12/2010
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5. Estudo do Limiar Nociceptivo durante Privação de Sono utilizando o Potencial Evocado por Laser / Nociceptive Threshold Investigation during Sleep Deprivation by means of the Laser Evoked Potential.
In the present study, we investigated the effects of total and REM sleep deprivation on the thermal nociceptive threshold using the laser-evoked potential (LEP). Twenty-eight male adult volunteers were randomly assigned to groups of Control (CTRL), Total (T-SD) and REM (REM-SD) sleep deprivation. Pain parameters, such as thermal noxious and warmth thresholds
Publicado em: 2010
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6. Efeito da Privação e da Restrição de sono sobre a densidade de receptores de andrógeno e de glicocorticóide no músculo esquelético / Effects of paradoxical sleep deprivation and sleep restriction upon de glucocorticoid and androgen receptors in skeletal muscle
Objetivo: Investigar o efeito da privação do sono paradoxal por 96 horas e a restrição do sono por 21 dias na densidade de receptores de glicocorticóide e de andrógenos no músculo esquelético gastrocnêmio. Métodos: Ratos machos de 3 meses de idade foram distribuídos em 6 grupos experimentais (controle, privados de sono paradoxal por 96h e rebote d
Publicado em: 2010
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7. Paradoxical sleep deprivation: neurochemical, hormonal and behavioral alterations. Evidence from 30 years of research
O sono ocupa cerca de um terço de nossas vidas, entretanto seu impacto na saúde e sua influência nas condições patológicas ainda não foi completamente elucidado. A prevalência dos distúrbios de sono é cada vez maior, sobretudo nas regiões mais industrializadas, repercutindo diretamente no bem-estar da população. Este artigo tem como objetivo sin
Anais da Academia Brasileira de Ciências. Publicado em: 2009-09
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8. Effects of cocaine, methamphetamine and modafinil challenge on sleep rebound after paradoxical sleep deprivation in rats
Sleep loss is both common and critically relevant to our society and might lead to the abuse of psychostimulants such as amphetamines, cocaine and modafinil. Since psychoactive substance abuse often occurs within a scenario of sleep deficit, the purpose of this investigation was to compare the sleep patterns of rats challenged with cocaine (7 mg/kg, ip), met
Brazilian Journal of Medical and Biological Research. Publicado em: 2008-01
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9. Effect of sildenafil (Viagra®) on the genital reflexes of paradoxical sleep-deprived male rats
Since there is evidence that paradoxical sleep deprivation (PSD) elicits penile erection (PE) and ejaculation (EJ), and that the erectile response of rats is mediated by nitric oxide, the present study sought to extend the latter finding by assessing the effects of sildenafil on the genital reflexes of male Wistar rats subjected to PSD. We also determined th
Brazilian Journal of Medical and Biological Research. Publicado em: 22/10/2007
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10. Different stress modalities result in distinct steroid hormone responses by male rats
Since both paradoxical sleep deprivation (PSD) and stress alter male reproductive function, the purpose of the present study was to examine the influence of PSD and other stressors (restraint, electrical footshock, cold and forced swimming, N = 10 per group) on steroid hormones in adult Wistar male rats. Rats were submitted to chronic stress for four days. T
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-06
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11. Paradoxical sleep deprivation increases plasma endothelin levels
The endothelins (ET-1, 2 and 3) constitute a family of 21 amino acid peptides with potent biological activities. ET-1 is one of the most potent endogenous vasoconstrictors so far identified and its increased concentration in plasma appears to be closely related to the pathogenesis of arterial hypertension as well as to obstructive sleep apnea (OSA). OSA pati
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-01
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12. Neuroleptic Drugs Revert the Contextual Fear Conditioning Deficit Presented by Spontaneously Hypertensive Rats: A Potential Animal Model of Emotional Context Processing in Schizophrenia?
Schizophrenia, bipolar disorder, and attention deficit/hyperactivity disorder (ADHD) present abnormalities in emotion processing. A previous study showed that the spontaneously hypertensive rats (SHR), a putative animal model of ADHD, present reduced contextual fear conditioning (CFC). The aim of the present study was to characterize the deficit in CFC prese
Oxford University Press.