Paracoccidoides Brasiliensis
Mostrando 1-4 de 4 artigos, teses e dissertações.
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1. Purificação parcial das quitinases, Pbcts1 e Pbcts2, do fungo Paracoccidiodes brasiliensis / Partial purification of chitinases, and Pbcts1 Pbcts2, fungus Paracoccidioides brasiliensis
Paracoccidoides brasiliensis is a human pathogenic dimorphic fungus. The recombinant chitinase from P. brasiliensis, Pbcts1r, was overexpressed in Escherichia coli using pET-32a (+) as vector. The enzyme was produced as inclusion bodies and became soluble by Sarkosyl being purified by a single step using a Ni-NTA resin. Pbcts1r showed activity against 4-MU-(
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/04/2008
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2. Predição de RNAs não-codificadores no transcriptoma do fungo Paracoccidioides brasiliensis usando aprendizagem de máquina
Paracoccidioides brasiliensis (Pb) is a saprophytic and dimorphic fungus of clinical importance because its propagules, when inhaled by humans, cause the disease known as paracoccidioidomycosis. In the year 2005 the Pb transcriptome was published, pointing out several potential drug targets, but still a significative amount of sequenced transcripts lack iden
Publicado em: 2008
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3. Análise de polimorfismo no gene CTLA-4 em pacientes com paracoccidioidomicose
The CTLA-4 protein is mainly expressed in activated T cells and plays an essential role in the immune response through its regulatory effect on T cell activation. This activity is mediated by the binding of CTLA-4 to molecules of the B7 family that are expressed by antigen-presenting cells. Polymorphisms of the CTLA-4 gene have been correlated to several aut
Publicado em: 2008
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4. Morphological Transition of Paracoccidioides brasiliensis Conidia to Yeast Cells: In Vivo Inhibition in Females
Clinical paracoccidioidomycosis is 13 times more common in men than in women. Estrogen inhibits the transition of mycelia or conidia (the saprophytic form of Paracoccidoides brasiliensis) to yeasts (the parasitic form) in vitro. Here, we show that, in male mice that were infected intranasally (mimicking natural infection) the transition of conidia in broncho
American Society for Microbiology.