Oxidative Phosphorylation
Mostrando 13-24 de 606 artigos, teses e dissertações.
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13. Efeito da solução salina hipertônica nas lesões resultantes da isquemia/reperfusão hepática: estudo experimental em ratos / Effect of hypertonic saline solution during ischemia/reperfusion injury in rat liver
Introduction: During liver ischemia, the drop in mitochondrial energy production leads to cellular damage, which is aggravated during restoration of blood supply. Besides local hepatic injury, the ischemia/reperfusion process can trigger a systemic inflammatory syndrome producing remote organ damage. To control these alterations in clinical conditions like l
Publicado em: 2008
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14. Atividade de fosfatases em duas cepas de Trypanosoma cruzi
Trypanosoma cruzi, the etiological agent of Chagas`disease, displays a remarkably high degree of both, structural and functional intraspecific heterogeneity, which could modulate its pathogenicity, survival and adaptability. In higher eukaryotes, phosphorylation and dephosphorylation are fundamental pathways that regulate a wide variety of cellular events. T
Publicado em: 2008
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15. Estudos funcionais e estruturais da proteina humana hnRNP Q/NSAP1 / Funcional and structural studies of human protein hnRNPQ
The members of the hnRNPs family (heterogenous nuclear ribonuclein proteins) play important roles in gene expression control and mRNAs metabolism. The proteins hnRNPD (AUF1) and hnRNPQ (NSAP1) were the main targets of this study. AUF1 has two RNA recognition motifs (RRM) and participates in the process of destabilization of a class of mRNAs that contain AU-r
Publicado em: 2008
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16. Nitric oxide and experimental periodontitis: characterization of intracellular mediators of osteoclastogenic activity, local and systemic consequences. / Óxido nítrico e periodontite experimental: caracterização de mediadores intracelulares da atividade osteoclastogênica, conseqüências locais e sistêmicas.
The periodontal disease is the most prevalent chronic disease in oral diseases. Among the mediators of this process, is the Resolvin E1 (RvE1), a novel mediator pro-resolving of inflammation that is capable to decrease alveolar bone loss secondary to periodontal disease in rabbits; and the nitric oxide (NO), that can be produced in large amount, induced by c
Publicado em: 2008
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17. Effect of surfactants and methodologic alterations in the rat inner mitochondrial membrane solubilization analysed by native and two dimensional electrophoresis / Efeito de surfatantes e modificações metodologicas na solubilização de membrana mitocondrial interna de ratos analisada por eletroforese nativa e bidimensional
The majority of the chemical energy produced inside aerobic cells is a result of the oxidative phosphorylation of ATP, inside the mitochondria. A great part of mitochondria proteins are organized into complexes located in the inner mitochondria membrane. Isolation and identification of those proteins have been conducted by electrophoresis, both in native as
Publicado em: 2008
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18. DETERMINATION OF SN IN HUMAN MILK BY GRAPHITE FURNACE ATOMIC ABSORPTION SPECTROMETRY / DETERMINAÇÃO DE SN EM LEITE HUMANO POR ESPECTROMETRIA DE ABSORÇÃO ATÔMICA NO FORNO DE GRAFITE
Tin is a metal of natural occurrence which is mainly extracted from the mineral cassiterite, SnO2. Tin may be released to the atmosphere from both natural and anthropogenic sources. In nature, it occurs in both inorganic and organic forms, and the shorter the organic chain associated to the metal, the higher the toxicity of the compound. Organotin compounds
Publicado em: 2008
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19. Aspectos do envelhecimento cerebral e função cognitiva em modelo experimental animal e estudo de mecanismos de neurodegeneração em cultura celular
The two phenomena, biological and behavioural, approached in the present work are brain aging and spatial memory. Several studies, comparative and experimental, have shown that aged subjects present significantly impaired performances in different types of cognitive tasks. It is also known that contradictions in literature exist in relation to consequences o
Publicado em: 2007
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20. Liver mitochondrial dysfunction and oxidative stress in the pathogenesis of experimental nonalcoholic fatty liver disease
Oxidative stress and hepatic mitochondria play a role in the pathogenesis of nonalcoholic fatty liver disease. The aim of the present study was to evaluate the role of hepatic mitochondrial dysfunction and oxidative stress in the pathogenesis of the disease. Fatty liver was induced in Wistar rats with a choline-deficient diet (CD; N = 7) or a high-fat diet e
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-02
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21. Bloqueio da fosforilação oxidativa no cultivo de embriões bovinos / Oxidative phosphorylation blockage of bovine culture embryos
Although in vitro embryo production has been improved in the last 2 decades, about 60% of the oocytes do not reach the blastocyst stage and embryo quality is very variable when compared with in vivo produced embryo. This developmental block can be affected by inorganic ions, buffers, aminoacids and gaseous atmosphere composition. The knowledge that there inf
Publicado em: 2006
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22. Mitochondrial K+ transport and cardiac protection during ischemia/reperfusion
Mitochondrial ion transport, oxidative phosphorylation, redox balance, and physical integrity are key factors in tissue survival following potentially damaging conditions such as ischemia/reperfusion. Recent research has demonstrated that pharmacologically activated inner mitochondrial membrane ATP-sensitive K+ channels (mitoK ATP) are strongly cardioprotect
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-03
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23. MITOCHONDRIAL PROTEIN EXPRESSION IN NATURAL AND INDUCED FORMS OF CANINE DILATED CARDIOMYOPATHY
Idiopathic dilated cardiomyopathy (DCM) is now widely regarded as a syndrome in which a variety of etiological and predisposing factors give rise to myocardial dysfunction ultimately reflected in a similar pathological condition. DCM is the most well-known myocardial disease in dogs characterized by ventricular dilation and diminished cardiac function. The p
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2005
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24. Respiration, oxidative phosphorylation, and uncoupling protein in Candida albicans
The respiration, membrane potential (Dy), and oxidative phosphorylation of mitochondria in situ were determined in spheroplasts obtained from Candida albicans control strain ATCC 90028 by lyticase treatment. Mitochondria in situ were able to phosphorylate externally added ADP (200 µM) in the presence of 0.05% BSA. Mitochondria in si
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-10