Oxa 23
Mostrando 1-12 de 68 artigos, teses e dissertações.
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1. Investigation of carbapenemases and aminoglycoside modifying enzymes of Acinetobacter baumannii isolates recovered from patients admitted to intensive care units in a tertiary-care hospital in Brazil
Abstract INTRODUCTION: Acinetobacter baumannii are opportunistic bacteria, highly capable of acquiring antimicrobial resistance through the production of carbapenemases and aminoglycoside modifying enzymes (AMEs). METHODS: Carbapenemase and AME genes were investigated in A. baumannii recovered from inpatients of a Brazilian hospital. RESULTS: The key gen
Rev. Soc. Bras. Med. Trop.. Publicado em: 20/12/2019
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2. Acinetobacter baumannii infections in Amazon Region driven by extensively drug resistant international clones, 2016-2018
BACKGROUND Acinetobacter baumannii is a leading cause of nosocomial infections. This species is characterised by the presence of pandemic lineages (International Clones) that present a broad antimicrobial resistance profile. OBJECTIVE To perform the molecular epidemiology of carbapenem-resistant A. baumannii from a clinical setting in the Amazon Basin, an
Mem. Inst. Oswaldo Cruz. Publicado em: 25/11/2019
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3. Antibiotic resistance in surface waters from a coastal lagoon of Southern Brazil under the impact of anthropogenic activities
Resumo Resíduos oriundos de atividades humanas podem atingir corpos d'água e contribuir significativamente para a presença de populações bacterianas resistentes a antibióticos. O objetivo deste estudo foi avaliar populações de bactérias cultiváveis resistentes a antibióticos em uma lagoa costeira impactada por atividades como agricultura e urbaniz
Rev. Ambient. Água. Publicado em: 10/10/2019
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4. High rate of detection of OXA-23-producing Acinetobacter from two general hospitals in Brazil
Abstract INTRODUCTION In recent decades, the prevalence of carbapenem-resistant Acinetobacter isolates has increased, and the production of oxacillinase (OXA)-type carbapenemases is the main mechanism underlying resistance. We evaluated OXA production from 114 Acinetobacter isolates collected between March and December 2013 from different clinical specimen
Rev. Soc. Bras. Med. Trop.. Publicado em: 05/09/2019
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5. Multidrug-resistant Klebsiella pneumoniae: genetic diversity, mechanisms of resistance to polymyxins and clinical outcomes in a tertiary teaching hospital in Brazil
ABSTRACT Increased resistance to polymyxin in Klebsiella pneumoniae (ColRKP) has been observed. Molecular epidemiology, as well as the clinical impact of these difficult to treat pathogens need to be better characterized. We present the clinical outcomes of 28 patients infected by ColRKP in a tertiary hospital. Isolates with MIC >2 by Vitek 2 were confirmed
Rev. Inst. Med. trop. S. Paulo. Publicado em: 19/06/2019
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6. Acinetobacter baumannii resistente aos carbapenêmicos no Brasil: perfil de suscetibilidade e diversidade de oxacilinases
RESUMO Introdução: O complexo Acinetobacter calcoaceticus-baumannii (ABC) inclui cinco espécies, sendo A. baumannii a mais importante clinicamente por carrear muitos mecanismos de resistência aos carbapenêmicos, sobretudo as oxacilinases. Objetivos: Os objetivos deste estudo foram identificar as espécies do complexo ABC, avaliar o perfil de suscetibi
J. Bras. Patol. Med. Lab.. Publicado em: 2017-11
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7. Prevalência e perfil de suscetibilidade aos antimicrobianos de bactérias do grupo ESKAPE no Distrito Federal, Brasil
RESUMO Introdução: Os principais patógenos causadores de infecções nosocomiais foram resumidos pela sigla ESKAPE, que são as iniciais das seguintes bactérias: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumanni, Pseudomonas aeruginosa e Enterobacter spp., as quais possuem altas taxas de resistência por consegui
J. Bras. Patol. Med. Lab.. Publicado em: 2017-08
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8. Modified Carba NP test for the detection of carbapenemase production in gram-negative rods: optimized handling of multiple samples
Abstract The modified Carba NP test presented here may be a valuable tool for laboratories interested in investigating a large number of carbapenemase-producing bacteria in a less-costly way. The test was evaluated against 48 carbapenemase-producing and carbapenemase-non-producing gram-negative bacteria. No false–positive results were obtained, but false-n
Braz. J. Microbiol.. Publicado em: 2017-06
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9. Molecular detection of β-lactamase and integron genes in clinical strains of Klebsiella pneumoniae by multiplex polymerase chain reaction
Abstract INTRODUCTION: Infections caused by β-lactamase-producing gram-negative bacteria, such as Klebsiella pneumoniae, are increasing globally with high morbidity and mortality. The aim of the current study was to determine antimicrobial susceptibility patterns and the prevalence of antibiotic resistance genes (β-lactamase and integron genes) using mul
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-06
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10. Carbapenem-resistant Acinetobacter baumannii contamination in an intensive care unit
Abstract INTRODUCTION: Acinetobacter baumannii is a major pathogen causing infections in intensive care units (ICUs). In this study, we aimed to evaluate the presence of A. baumannii in an ICU environment and gloves from ICU workers and to characterize the antimicrobial resistance of the isolates in comparison with those isolated from ICU patients at the sa
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-03
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11. Clinical and microbiological characteristics of OXA-23- and OXA-143-producing Acinetobacter baumannii in ICU patients at a teaching hospital, Brazil
ABSTRACT Background: Carbapenem-resistant Acinetobacter baumannii (CRAb) is an important cause of nosocomial infections especially in intensive care units. This study aimed to assess clinical aspects and the genetic background of CRAb among ICU patients at a Brazilian teaching hospital. Methods: 56 critically ill patients colonized or infected by CRAb, dur
Braz J Infect Dis. Publicado em: 2016-12
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12. Detecção de genes de resistência a antimicrobianos em Klebsiella pneumoniae produtoras de betalactamases e carbapenemases por culturas de vigilância de pacientes em uma unidade de terapia intensiva no Rio de Janeiro, Brasil
RESUMO Introdução: O aumento da incidência de microrganismos multirresistentes é considerado um dos principais problemas de saúde pública. Uma das rotinas incluídas na prática hospitalar é a busca de pacientes colonizados e/ou infectados. Objetivo: Avaliar a variabilidade genética e as relações clonais de K. pneumoniae produtoras de betalactama
J. Bras. Patol. Med. Lab.. Publicado em: 2016-10