Optic Network
Mostrando 13-21 de 21 artigos, teses e dissertações.
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13. Optic nerve head blood flow using a laser Doppler velocimeter and haemorheology in primary open angle glaucoma and normal pressure glaucoma.
Optic disc blood flow velocity was measured in healthy patients, those with primary open angle glaucoma (POAG), and patients with normal pressure glaucoma (NPG). The velocity of the red blood cells (RBCs) in the capillaries of the optic nerve head (ONH) has been measured with a laser Doppler velocimeter (LDV), and blood viscosity has been evaluated notably b
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14. Structural brain mutant of Drosophila melanogaster with reduced cell number in the medulla cortex and with normal optomotor yaw response
KS58, one out of six known alleles of the small optic lobes (sol) gene in Drosophila melanogaster, reduces the cell number in the medulla cortex by degeneration of ganglion cells in the pupae to about 50%. Also, about half the volume of the medulla and lobula complex neuropils is missing. Many Golgistained cells in the mutant optic lobes resemble their homol
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15. Deciphering a neural code for vision
Deciphering the information that eyes, ears, and other sensory organs transmit to the brain is important for understanding the neural basis of behavior. Recordings from single sensory nerve cells have yielded useful insights, but single neurons generally do not mediate behavior; networks of neurons do. Monitoring the activity of all cells in a neural network
The National Academy of Sciences of the USA.
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16. SLP-2 is required for stress-induced mitochondrial hyperfusion
Mitochondria are dynamic organelles, the morphology of which results from an equilibrium between two opposing processes, fusion and fission. Mitochondrial fusion relies on dynamin-related GTPases, the mitofusins (MFN1 and 2) in the outer mitochondrial membrane and OPA1 (optic atrophy 1) in the inner mitochondrial membrane. Apart from a role in the maintenanc
Nature Publishing Group.
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17. Binocular disparity discrimination in human cerebral cortex: functional anatomy by positron emission tomography.
Neurobiological studies in higher primates indicate that the processing of stereoscopic information takes place at early levels in the visual cortex. To map the anatomical structures in the human brain participating in pure stereopsis based upon binocular disparity, we measured with positron emission tomography the changes in regional cerebral blood flow as
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18. OPA1 requires mitofusin 1 to promote mitochondrial fusion
The regulated equilibrium between mitochondrial fusion and fission is essential to maintain integrity of the organelle. Mechanisms of mitochondrial fusion are largely uncharacterized in mammalian cells. It is unclear whether OPA1, a dynamin-related protein of the inner membrane mutated in autosomal dominant optic atrophy, participates in fusion or fission. O
National Academy of Sciences.
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19. Choice reaction time performance correlates with diffusion anisotropy in white matter pathways supporting visuospatial attention
Humans exhibit significant interindividual variability in behavioral reaction time (RT) performance yet the underlying neural mechanisms for this variability remain largely unknown. It has been proposed that interindividual variability in RT performance may be due to differences in white matter (WM) physiological properties, although such a relationship has
National Academy of Sciences.
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20. Zebrafish zic2a patterns the forebrain through modulation of Hedgehog-activated gene expression
Holoprosencephaly (HPE) is the most common congenital malformation of the forebrain in human. Several genes with essential roles during forebrain development have been identified because they cause HPE when mutated. Among these are genes that encode the secreted growth factor Sonic hedgehog (Shh) and the transcription factors Six3 and Zic2. In the mouse,
Company of Biologists.
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21. Statistics of the maintained discharge of cat retinal ganglion cells.
Action potentials were recorded from single fibres in the optic tracts of anaesthetized cats. Continuous records were obtained at various levels of scotopic and mesopic retinal illumination. In some cases, the light intensity was modulated by a pseudorandom Gaussian white-noise signal. The maintained discharge of on-centre neurones increased while the mainta