Open Box
Mostrando 1-12 de 181 artigos, teses e dissertações.
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1. “Black box” pharmacogenetic decision-support tools in psychiatry
Objective: Anxiety and depression are prevalent among medical students. Brazilian medical students have higher levels of depression and lower quality of life than their U.S. counterparts, and no preventive intervention exists for this risk group in Brazil. The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP), a cognitive-behavioral
Braz. J. Psychiatry. Publicado em: 2020-04
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2. O ETANOL DE SEGUNDA GERAÇÃO NO BRASIL: POLÍTICAS E REDES SOCIOTÉCNICAS
O presente artigo propõe analisar as políticas e as iniciativas nacionais relacionadas com a produção, a pesquisa e o desenvolvimento de etanol de segunda geração (E2G) no Brasil. Utilizando a Teoria Ator-Rede como referencial teórico e metodológico, buscamos identificar, a partir de levantamento bibliográfico e documental, quais são as políticas
Rev. bras. Ci. Soc.. Publicado em: 23/09/2019
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3. INFLUENCE OF ACUTE PHYSICAL EXERCISE ON COGNITIVE AND MOTOR BEHAVIOR IN AN EXPERIMENTAL MODEL OF ALZHEIMER'S DISEASE
RESUMO Introdução: O envelhecimento causa alterações de diversas funções executivas e cognitivas, principalmente relacionadas à incidência de demências, em especial, a doença Alzheimer (DA). Diversos estudos mencionam o exercício físico como um recurso preventivo de sintomas de depressão. Objetivo: Investigar as alterações cognitivas e compo
Rev Bras Med Esporte. Publicado em: 2019-04
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4. Relationship Between the Anxious Symptoms and the Neurotransmitter in Parkinson's Mice with Different Dosages of MPTP
ABSTRACT This study aims to explore the relationship between the anxious symptoms and the impairment of 5-hydroxytryptamine system in PD mice induced by different dosages of MPTP. The mice from the three model groups, the low-dose, dose and high-dose group, took longer time in the dark box than those in the control group (P<0.05). However, no statistically s
Braz. arch. biol. technol.. Publicado em: 14/11/2018
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5. Intranasal mucoadhesivemicroemulsion for neuroprotective effect of curcuminin mptp induced Parkinson model
ABSTRACT This study was to investigate the neuroprotective effect of curcumin against inflammation-mediated dopaminergic neurodegeneration in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mice model of Parkinson's disease (PD). Curcumin loaded sodium hyaluronate based mucoadhesive microemulsion (CMME) was developed by using Box Behnken design of Respon
Braz. J. Pharm. Sci.. Publicado em: 22/06/2017
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6. Opening the black box of collaborative writing: experiences from a teamwork-based course in industrial management
Abstract In this paper we discuss the introduction of collaborative writing (CW) tools in a course designed with learning activities based on problem-based learning (PBL), authentic case methodology, and teamwork. We argue that CW is a vital, but poorly understood, part of teamwork, and a black-box activity. Our ambition is to open the black box of CW and di
Prod.. Publicado em: 29/05/2017
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7. Activation of locus coeruleus heme oxygenase-carbon monoxide pathway promoted an anxiolytic-like effect in rats
The heme oxygenase-carbon monoxide pathway has been shown to play an important role in many physiological processes and is capable of altering nociception modulation in the nervous system by stimulating soluble guanylate cyclase (sGC). In the central nervous system, the locus coeruleus (LC) is known to be a region that expresses the heme oxygenase enzyme (HO
Braz J Med Biol Res. Publicado em: 08/04/2016
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8. IPH-Hydro Tools: uma ferramenta open source para determinação de informações topológicas em bacias hidrográficas integrada a um ambiente SIG
RESUMO A delimitação de bacias hidrográficas, geração da rede de drenagem e determinação de características hidráulicas de um rio de interesse são partes importantes de estudos na área de hidrologia. Atualmente muitas dessas informações são obtidas com o processamento de modelos digitais de elevação (MDEs) em softwares comerciais de SIG, como
RBRH. Publicado em: 2016-03
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9. Characterization and expression analysis of WOX2 homeodomain transcription factor in Aegilops tauschii
The WUSCHEL (WUS)-related homeobox (WOX) gene family coordinates transcription during the early phases of embryogenesis. In this study, a putative WOX2 homolog was isolated and characterized from Aegilops tauschii, the donor of D genome of Triticum aestivum. The sequence consisted of 2045 bp, and contained an open reading frame (ORF), encoded 322 amino acids
Genet. Mol. Biol.. Publicado em: 2015-03
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10. Myocardial ischemic preconditioning upregulated protein 1(Mipu1):zinc finger protein 667 - a multifunctional KRAB/C2H2 zinc finger protein
Myocardial ischemic preconditioning upregulated protein 1 (Mipu1) is a newly discovered upregulated gene produced in rats during the myocardial ischemic preconditioning process. Mipu1 cDNA contains a 1824-base pair open reading frame and encodes a 608 amino acid protein with an N-terminal Krüppel-associated box (KRAB) domain and classical zinc finger C2H2 m
Braz J Med Biol Res. Publicado em: 31/10/2014
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11. Animal models of anxiety disorders and stress
Anxiety and stress-related disorders are severe psychiatric conditions that affect performance in daily tasks and represent a high cost to public health. The initial observation of Charles Darwin that animals and human beings share similar characteristics in the expression of emotion raise the possibility of studying the mechanisms of psychiatric disorders i
Rev. Bras. Psiquiatr.. Publicado em: 2013
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12. Estudo da atividade tipo-ansiolítica das folhas de Pimenta pseudocaryophyllus (Gomes) L.R. Landrum - Myrtaceae / Anxiolity - like activity of the leaves of Pimenta pseudocaryophyllus (Gomes) L.R. Landrum - Myrtaceae
Pimenta pseudocaryophyllus, popularly known as Craveiro, is the only species in this genus native to the cerrado of Brazil. Ethnopharmacological studies revealed medicinal use of P. pseudocaryophyllus extracts in treating menstrual and digestive problems as well as emotional tension in the form of soothing tea among other therapeutic applications in Brazilia
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/02/2012