Oligomeric Interface
Mostrando 1-12 de 23 artigos, teses e dissertações.
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1. Evaluation of the Mechanic and Electrochemical Properties of an Epoxy Coating with Addition of Different Polyhedral Oligomeric Silsesquioxanes (POSS) Applied on Substrate of Low Alloy Steel
The epoxy resin is one of the matrices most employed in obtaining composites and coatings. Its properties have been modified using materials such as clays and polyhedral oligomeric silsesquioxanes - POSS. The use of POSS in the preparation of thermosetting nanocomposites has been studied in obtaining hybrid materials with higher mechanic and surface properti
Mat. Res.. Publicado em: 31/07/2017
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2. Revelando as características do nano-ambiente das interfaces entre proteinas / Characteristics of protein interface nano-environment revealed
Dentro do ambiente celular, há uma variedade de moléculas e a interação entre si regulam praticamente todos os processos necessários e essenciais para a manutenção da vida. Interações entre proteínas estão envolvidas no controle de vários processos intra e intercelulares, como regulação metabólica e da expressão gênica, reconhecimento antíg
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/08/2012
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3. Interaction of hidrophilic porphyrins and extracellular hemoglobin with biomimetic models of biological membranes / Interação de porfirinas hidrofílicas e de hemoglobina extracelular com modelos biomiméticos de membrana biológica
In the first part of this work interactions of the cationic meso tetrakis (4-N-methilpyridil) porphyrin (TMPyP) and meso-tetrakis (4-sulfonatophenyl) porphyrin (TPPS4) in the free base forms with membrane model systems (ionic micelles, mixed micelles and phospholipids vesicles) in aqueous solutions, have been investigated by optical absorption, resonance lig
Publicado em: 2008
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4. Avaliação da espressão de glicoproteinas potencialmente especificas na membrana plasmatica de celulas Natural Killer uterinas de camundogos / Evaluation of expression of potentially specific glycoproteins in plasmatic membrane of mouse uterine Natural Killer
The phenomenon of pregnancy in mammalians with hemochorial type placenta ions where the allogeneic fetus presenting the half of gene from paternal origins growth in tight contact with maternal tissues, without triggering the rejections responses of maternal immune system is still a non-solved question of immunology of reproduction. The cross-talk at maternal
Publicado em: 2006
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5. Identification of protein oligomerization states by analysis of interface conservation
The discrimination of true oligomeric protein–protein contacts from nonspecific crystal contacts remains problematic. Criteria that have been used previously base the assignment of oligomeric state on consideration of the area of the interface and/or the results of scoring functions based on statistical potentials. Both techniques have a high success
The National Academy of Sciences.
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6. Probing the interface in a human co-chaperonin heptamer: residues disrupting oligomeric unfolded state identified
BioMed Central.
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7. T cells specific for alpha-beta interface regions of hemoglobin recognize the isolated subunit but not the tetramer and indicate presentation without processing.
Processing of a protein antigen into fragments is believed to be a prerequisite for its presentation by the antigen-presenting cell to the T cell. This model would predict that, in oligomeric proteins, T cells prepared with specificity for regions that are buried within subunit association surfaces should recognize the respective regions in vitro equally wel
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8. Design, creation, and characterization of a stable, monomeric triosephosphate isomerase.
Protein engineering on trypanosomal triosephosphate isomerase (TIM) converted this oligomeric enzyme into a stable, monomeric protein that is enzymatically active. Wild-type TIM consists of two identical subunits that form a very tight dimer involving interactions of 32 residues of each subunit. By replacing 15 residues of the major interface loop by another
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9. A meanfield approach to the thermodynamics of a protein-solvent system with application to the oligomerization of the tumor suppressor p53
The thermodynamic stability and oligomerization status of the tumor suppressor p53 tetramerization domain have been studied experimentally and theoretically. A series of hydrophilic mutations at Met-340 and Leu-344 of human p53 were designed to disrupt the hydrophobic dimer–dimer interface of the tetrameric oligomerization domain of p53 (residues 325–355
The National Academy of Sciences.
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10. Comparison of the protein–protein interfaces in the p53–DNA crystal structures: Towards elucidation of the biological interface
p53, the tumor suppressor protein, functions as a dimer of dimers. However, how the tetramer binds to the DNA is still an open question. In the crystal structure, three copies of the p53 monomers (containing chains A, B, and C) were crystallized with the DNA-consensus element. Although the structure provides crucial data on the p53–DNA contacts, the active
National Academy of Sciences.
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11. Insights into the quaternary association of proteins through structure graphs: a case study of lectins
The unique three-dimensional structure of both monomeric and oligomeric proteins is encoded in their sequence. The biological functions of proteins are dependent on their tertiary and quaternary structures, and hence it is important to understand the determinants of quaternary association in proteins. Although a large number of investigations have been carri
Portland Press Ltd..
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12. The Crystal Structure of the Phosphorylation Domain in PhoP Reveals a Functional Tandem Association Mediated by an Asymmetric Interface
PhoP from Bacillus subtilis belongs to the OmpR subfamily of response regulators. It regulates the transcription of several operons and participates in a signal transduction network that controls adaptation of the bacteria to phosphate deficiency. The receiver domains of two members of this subfamily, PhoB from Escherichia coli and DrrD from Thermotoga marit
American Society for Microbiology.