Oligoclonal Bands
Mostrando 13-24 de 52 artigos, teses e dissertações.
-
13. CSF oligoclonal IgG bands in a patient with torsion dystonia.
-
14. A prospective study on the predictive value of CSF oligoclonal bands and MRI in acute isolated neurological syndromes for subsequent progression to multiple sclerosis.
A prospective study in patients with a clinical acute isolated brainstem or spinal cord disorder was undertaken. The aim was to evaluate the predictive value of IgG intrathecal synthesis (through the detection of oligoclonal bands in CSF) and MRI lesions at presentation, for the subsequent progression to multiple sclerosis. Forty four patients took part in t
-
15. Oligoclonal IgG Antibody Response in the Central Nervous System to Different Measles Virus Antigens in Subacute Sclerosing Panencephalitis
Agarose electrophoresis of cerebrospinal fluid from two patients with subacute sclerosing panencephalitis revealed in both cases several homogeneous bands in the intermediate and basic gammaglobulin region. The bands were identified as IgG with various degrees of kappa or lambda light-chain restriction in crossed immunoelectrophoresis.
-
16. Intrathecal synthesis of anti-mycobacterial antibodies in patients with tuberculous meningitis. An immunoblotting study.
Cerebrospinal fluid (CSF) and serum samples from eight patients with bacteriologically proven (6) or clinically suspected (2) tuberculous meningitis were tested for the presence of anti-mycobacterial IgG antibodies by an affinity-mediated immunoblot technique. This technique is based on agarose gel isoelectric focusing of paired CSF and serum samples diluted
-
17. Sequential changes in oligoclonal patterns during the course of multiple sclerosis.
The majority of patients with multiple sclerosis have an abnormality of their spinal fluid immunoglobulins. This alteration is manifested as patterns of diffuse protein bands in the gamma globulin region following electrophoresis. This pattern has been termed one of restricted heterogeneity, or an oligoclonal pattern. We have found changes in the banding pat
-
18. Sequential changes in oligoclonal patterns during the course of multiple sclerosis.
The majority of patients with multiple sclerosis have an abnormality of their spinal fluid immunoglobulins. This alteration is manifested as patterns of diffuse protein bands in the gamma globulin region following electrophoresis. This pattern has been termed one of restricted heterogeneity, or an oligoclonal pattern. We have found changes in the banding pat
-
19. Presence of oligoclonal immunoglobulin G bands and lack of matrix protein antibodies in cerebrospinal fluids and sera of ferrets with measles virus encephalitis.
Young adult ferrets were immunized with measles vaccine and 5 to 6 weeks later inoculated intracerebrally with Vero cells persistently infected with cell-associated strain D.R. of measles virus isolated from a patient with subacute sclerosing panencephalitis. Of nine ferrets which survived the infection for 3 weeks or longer, five showed neurological signs.
-
20. Cerebrospinal fluid in the diagnosis of multiple sclerosis: a consensus report.
The Committee of the European Concerted Action for Multiple Sclerosis (Charcot Foundation) organised five workshops to discuss CSF analytical standards in the diagnosis of multiple sclerosis. This consensus report from 12 European countries summarises the results of those workshops. It is hoped that neurologists will confer with their colleagues in clinical
-
21. Immunoglobulin and other proteins in the cerebrospinal fluid of patients with Alzheimer's disease.
Immunoglobulin has been measured and studied electrophoretically in cerebrospinal fluid (CSF) from 14 patients with Alzheimer's disease and 25 undemented controls. Presence or absence of the diagnosis of Alzheimer's disease was confirmed histologically, as these were postmortem specimens. There was no increased incidence of oligoclonal IgG bands in either gr
-
22. Antibody synthesis within the central nervous system: comparisons of CSF IgG indices and electrophoresis
Various laboratories have reported differing success rates in their ability to detect intrathecal synthesis of antibody when comparing the index of [Formula: see text] with electrophoretic analysis. We selected 44 patients in the borderline area of minimal and/or equivocal abnormality by IgG index. Electrophoretic analysis (on polyacrylamide gels for oligocl
-
23. Multiple sclerosis presenting with progressive visual failure.
Progressive visual failure as the presenting feature of multiple sclerosis is described in five patients. The clinical features did not permit a distinction from visual loss due to compression. The finding of oligoclonal bands in the CSF at presentation is a useful pointer to the diagnosis, but is not specific and full investigation to exclude treatable caus
-
24. Oligoclonal T cell receptor gene rearrangements in blood lymphocytes of patients with acute Epstein-Barr virus-induced infectious mononucleosis.
Gene rearrangement studies were performed on blood lymphocytes from eight patients with acute Epstein-Barr virus-induced infectious mononucleosis. The diagnosis in each case was based on characteristic clinical, hematologic, and serologic findings. The blood lymphocytes in each patient consisted predominantly of CD8+ T cells. EBV DNA was detected in seven pa