Nucleotide Synthesis
Mostrando 1-12 de 2008 artigos, teses e dissertações.
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1. Linkage disequilibrium, SNP frequency change due to selection, and association mapping in popcorn chromosome regions containing QTLs for quality traits
Abstract The objectives of this study were to assess linkage disequilibrium (LD) and selection-induced changes in single nucleotide polymorphism (SNP) frequency, and to perform association mapping in popcorn chromosome regions containing quantitative trait loci (QTLs) for quality traits. Seven tropical and two temperate popcorn populations were genotyped for
Genet. Mol. Biol.. Publicado em: 2016-03
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2. DNA repair diseases: what do they tell us about cancer and aging?
The discovery of DNA repair defects in human syndromes, initially in xeroderma pigmentosum (XP) but later in many others, led to striking observations on the association of molecular defects and patients' clinical phenotypes. For example, patients with syndromes resulting from defective nucleotide excision repair (NER) or translesion synthesis (TLS) present
Genet. Mol. Biol.. Publicado em: 2014
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3. Isolation of a yeast strain able to produce a polygalacturonase with maceration activity of cassava roots
The objective of the present study was the isolation of a yeast strain, from citrus fruit peels, able to produce a polygalacturonase by submerged fermentation with maceration activity of raw cassava roots. Among 160 yeast strains isolated from citrus peels, one strain exhibited the strongest pectinolytic activity. This yeast was identified as Wickerhamomyces
Food Sci. Technol. Publicado em: 24/05/2013
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4. Identification of novel single nucleotide polymorphisms in the DGAT1 gene of buffaloes by PCR-SSCP
Diacylglycerol O-acyltransferase 1 (DGAT1) is a microsomal enzyme that catalyzes the final step of triglyceride synthesis. The DGAT1 gene is a strong functional candidate for determining milk fat content in cattle. In this work, we used PCR-SSCP (polymerase chain reaction-single-strand conformation polymorphism) and DNA sequencing to examine polymorphism in
Genetics and Molecular Biology. Publicado em: 13/07/2012
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5. Carotenoid biosynthesis structural genes in carrot (Daucus carota): isolation, sequence-characterization, single nucleotide polymorphism (SNP) markers and genome mapping.
Carotenoid pigments are important components of the human diet and carrots are the main dietary sources of the vitamin A precursors IX- and /3- carotene. Carotenoids play essential biological roles in plants and the genes coding for the carotenoid pathway enzymes are evolutionarily conserved, but little information exists about these genes for carrot. In thi
Theoretical and Applied Genetics. Publicado em: 2011
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6. Equações estruturais aplicadas a modelos causais de câncer de pulmão / Structural equation models applied to lung cancer causal models
Introdução: O câncer de pulmão (CP) é o tipo de câncer que mais mata no mundo e o cigarro ainda é sua causa mais importante. Além disso, a alimentação tem sido associada ao CP, por ser fonte de vitaminas e aminoácidos que fazem parte do metabolismo do carbono (MC). O MC é considerado mecanismo chave na manutenção da integridade do DNA e na regu
Publicado em: 2011
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7. Promoter region sequence differences in the A and G gamma globin genes of Brazilian sickle cell anemia patients
Fetal hemoglobin (HbF), encoded by the HBG2 and HBG1 genes, is the best-known genetic modulator of sickle cell anemia, varying dramatically in concentration in the blood of these patients. This variation is partially associated with polymorphisms located in the promoter region of the HBG2 and HBG1 genes. In order to explore known and unknown polymorphisms in
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-08
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8. Espermadesinas caprinas caprinas (bodesinas): produção em sistema bacteriano. / Espermadesinas goat (bodesinas) production in bacterial system.
The low purification efficiency and the incomplete characterization of buck spermadhesins (Bdhs) prompted us to establish an effective system to produce recombinant Bdhs (rBdhs). The Bdh-2 and Bdh-4 cDNA was inserted in a prokaryotic expression plasmid pTrcHis TOPO. The pTrcHis-Bdh system was constructed to produce a His6 fusion protein in E. coli Top10 cell
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/08/2009
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9. NMDA receptor blockade alters the intracellular distribution of neuronal nitric oxide synthase in the superficial layers of the rat superior colliculus
Nitric oxide (NO) is a molecular messenger involved in several events of synaptic plasticity in the central nervous system. Ca2+ influx through the N-methyl-D-aspartate receptor (NMDAR) triggers the synthesis of NO by activating the enzyme neuronal nitric oxide synthase (nNOS) in postsynaptic densities. Therefore, NMDAR and nNOS are part of the intricate sce
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-02
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10. Uso de técnicas computacionais no estudo da transcrição e regulação gênica em Homo sapiens e Mus musculus / Use of computational methods to study the transcription and gene regulation in Homo sapiens and Mus musculus
Genes, nucleotide sequences necessary for the synthesis of functional molecules, are transcribed and regulated by extremely complex cellular and molecular processes. To understand when and in which tissues the genes are expressed, their functional isoforms, control regions and the factors involved in gene regulation is one of major challenges of modern molec
Publicado em: 2008
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11. Subcellular localization of sugarcane (Sccharum spp.) proteins : in silico characterization and functional evaluation / Localização subcelular de proteinas de cana-de-açucar (Sccharum spp.) : caracterização in silico e avaliação funcional
Plant cells are highly organized and many biological processes are associated with specialized subcellular structures. Subcellular localization is a key feature of proteins, since it is related to biological function. The determination of subcellular localization using computational prediction is a highly desirable strategy because experimental approaches ar
Publicado em: 2008
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12. Análise comparativa do genoma de dois isolados de Cowpea aphid-borne mosaic virus (CABMV) obtidos de diferentes hospedeiros / Comparative analysis of the genome of two isolates of Cowpea aphid-borne mosaic virus (CABMV) obtained from different hosts
In Brazil and in other countries where passionfruit is grown, the viral disease known as passionfruit woodiness is a limiting factor for production. For many years this disease was associated with a single potyvirus, Passion fruit woodiness virus (PWV). However, studies conducted over the last 20 years demonstrated that two additional potyviruses, Cowpea aph
Publicado em: 2007