Nucleator
Mostrando 1-12 de 19 artigos, teses e dissertações.
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1. Estimativa do número de cardiomiócitos do ventrículo esquerdo em suínos (Sus scrofa) / Estimation of the cardyomyocites number in the left ventrcle in swine (Sus scrofa)
Os estudos relacionados ao coração têm sido realizados ao longo dos anos de forma bastante comum, tendo em vista a grande importância que este órgão tem na medicina. Problemas relacionados ao mesmo são uma das principais causas de mortes e internações no Brasil e no mundo, por causa disso, avanços no que diz respeito a inovações tecnológicas e n
Publicado em: 2009
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2. Stereological tools in biomedical research
Estudos estereológicos são cada vez mais freqüentes na literatura, particularmente nos campos do desenvolvimento/evolução, patologia e neurociências. O desafio da estereologia é interpretar o arranjo estrutural tridimensional interno com base na análise de cortes da estrutura que mostram apenas uma informação bidimensional. São comentados nesta re
Anais da Academia Brasileira de Ciências. Publicado em: 2003-12
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3. Nucleator-dependent intercellular assembly of adhesive curli organelles in Escherichia coli.
Bacterial adhesion to other bacteria, to eukaryotic cells, and to extracellular matrix proteins is frequently mediated by cell surface-associated polymers (fimbriae) consisting of one or more subunit proteins. We have found that polymerization of curlin to fimbriae-like structures (curli) on the surface of Escherichia coli markedly differs from the prevailin
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4. The ActA protein of Listeria monocytogenes acts as a nucleator inducing reorganization of the actin cytoskeleton.
Listeria monocytogenes, a facultative intracellular pathogen, employs actin and other microfilament-associated proteins to move through the host cell cytoplasm. Isogenic mutants of L. monocytogenes lacking the surface-bound ActA polypeptide no longer interact with cytoskeletal elements and are, as a consequence, non-motile (Domann et al., 1992, EMBO J., 11,
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5. Antifreeze Proteins Modify the Freezing Process In Planta12
During cold acclimation, winter rye (Secale cereale L. cv Musketeer) plants accumulate antifreeze proteins (AFPs) in the apoplast of leaves and crowns. The goal of this study was to determine whether these AFPs influence survival at subzero temperatures by modifying the freezing process or by acting as cryoprotectants. In order to inhibit the growth of ice,
American Society of Plant Biologists.
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6. Cytoplasmic Dynein Nucleates Microtubules to Organize Them into Radial Arrays In Vivo
Numerous evidence demonstrates that dynein is crucial for organization of microtubules (MTs) into radial arrays, but its exact function in this process is unclear. Here, we studied the role of cytoplasmic dynein in MT radial array formation in the absence of the centrosome. We found that dynein is a potent MT nucleator in vitro and that stimulation of dynein
The American Society for Cell Biology.
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7. Three separate classes of bacterial ice nucleation structures.
Studies of the properties of the ice nucleation structure exposed on the surfaces of various bacteria such as Pseudomonas syringae, Erwinia herbicola, or various strains of Ice+ recombinant Escherichia coli have shown that there are clearly three major related but chemically distinct types of structures on these cells. First, the ability of Ice+ cells to nuc
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8. Formin1 disruption confers oligodactylism and alters Bmp signaling
Proper limb development requires concerted communication between cells within the developing limb bud. Several molecules have been identified which contribute to the formation of a circuitry loop consisting in large part of secreted proteins. The intracellular actin nucleator, Formin 1 (Fmn1), has previously been implicated in limb development, but questions
Oxford University Press.
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9. Neuronal number and volume alterations in the neocortex of HIV infected individuals.
Substantial neuronal loss in the superior frontal gyrus in patients who have died of AIDS have been reported previously. This investigation examined the distribution of neuronal loss in three other neocortical areas and, alteration in neuronal volume in four neocortical areas. This was carried out using two stereological probes, the "disector" and the "nucle
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10. RacGAP50C directs perinuclear γ-tubulin localization to organize the uniform microtubule array required for Drosophila myotube extension
The microtubule (MT) cytoskeleton is reorganized during myogenesis as individual myoblasts fuse into multinucleated myotubes. Although this reorganization has long been observed in cell culture, these findings have not been validated during development, and proteins that regulate this process are largely unknown. We have identified a novel postmitotic fu
Company of Biologists.
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11. Abl Interactor 1 (Abi-1) Wave-Binding and SNARE Domains Regulate Its Nucleocytoplasmic Shuttling, Lamellipodium Localization, and Wave-1 Levels
The Abl interactor 1 (Abi-1) protein has been implicated in the regulation of actin dynamics and localizes to the tips of lamellipodia and filopodia. Here, we show that Abi-1 binds the actin nucleator protein Wave-1 through an amino-terminal Wave-binding (WAB) domain and that disruption of the Abi-1-Wave-1 interaction prevents Abi-1 from reaching the tip of
American Society for Microbiology.
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12. Targeting of Listeria monocytogenes ActA protein to the plasma membrane as a tool to dissect both actin-based cell morphogenesis and ActA function.
Actin assembly on the surface of Listeria monocytogenes in the cytoplasm of infected cells provides a model to study actin-based motility and changes in cell shape. We have shown previously that the ActA protein, exposed on the bacterial surface, is required for polarized nucleation of actin filaments. To investigate whether plasma membrane-associated ActA c