Nitrosyl Ruthenium Complexes
Mostrando 1-12 de 17 artigos, teses e dissertações.
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1. The Ru-NO bonding in nitrosyl-[poly(1-pyrazolyl)borate]ruthenium complexes: a theoretical insight based on EDA
A labilidade do grupo NO+ em complexos [TpRuCl2(NO)]q (Tp = BL(pirazol-1-il)3) foi avaliada à luz da análise de decomposição de energia (Su-Li EDA). Os efeitos eletrônicos de diferentes substituintes pseudo-axiais (L = H, ânion pirazolato, pirazol, isoxazol e isotiazol) na natureza das ligações Ru-NO foram avaliados considerando-se os complexos no es
J. Braz. Chem. Soc.. Publicado em: 2013-09
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2. Efeitos de complexos de rutênio com ligante nitrosilo em anéis de aorta com e sem endotélio isoladas de ratos / Effects of rutheim complexes with nitrosyl ligand in aortic rings with and without endothelium isolated from rat
Not informed.
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/02/2012
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3. Nitric oxide synthesis and biological functions of nitric oxide released from ruthenium compounds
During three decades, an enormous number of studies have demonstrated the critical role of nitric oxide (NO) as a second messenger engaged in the activation of many systems including vascular smooth muscle relaxation. The underlying cellular mechanisms involved in vasodilatation are essentially due to soluble guanylyl-cyclase (sGC) modulation in the cytoplas
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-09
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4. Complexos fosfínicos de rutênio contendo os ligantes nitro, nitrosilo ou piridinas, com atividades antitumorais e antituberculose / Phosphine ruthenium complexes containing the ligands nitrite, nitrosyl or pyridines with antitumoral and antituberculosis activities
Neste trabalho, uma série de complexos cis-[RuCl(L)(dppb)(5-mebipy)]PF6 (L=piridina, 4-metilpiridina, 4-fenilpiridina, 4-vinilpiridina, 4-terc-butilpiridina e 4- aminopiridina); o cis-[RuCl(NO2)(dppb)(5-mebipy)], o cis-[Ru(NO2)2(dppb)(5- mebipy)], o ct-[RuCl(NO)(dppb)(5-mebipy)](PF6)2, e o cc-[RuCl(CH3CN)(dppb)(5- mebipy)]PF6 [dppb = 1,4-bis(difenilfosfina)
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 10/11/2010
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5. New nitric oxide donors based on ruthenium complexes
Nitric oxide (NO) donors produce NO-related activity when applied to biological systems. Among its diverse functions, NO has been implicated in vascular smooth muscle relaxation. Despite the great importance of NO in biological systems, its pharmacological and physiological studies have been limited due to its high reactivity and short half-life. In this rev
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-01
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6. Ruthenium(II) nitrosyls as radical scavenger / Nitrosilo complexos de rutênio(II) como captores de radicais de interesse biológico
The complexes trans-[Ru(NO)(NH3)4(L)](X)3 (1), [Ru(NO)(Hedta)] (2) and their synthetic precursors trans-[Ru(H2O)(NH3)4(L)](X)2 (3), trans-[Ru(SO4)(NH3)4(L)](X) (4) , where L = isn, nic, imN, 4-pic, py, P(OEt) e X = PF6 - and BF4 -, were tested as scavengers for the radicals DPPHo, OHo e O2 -o in aqueous media. The redox potential for the metal center in the
Publicado em: 2009
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7. Syntheses, Characterization and Chemical Reactivity of Chloro and Nitrosyl Complexes of trans-Tetrakispyridines of Ruthenium / Síntese, caracterização e reatividade química de complexos de cloro e nitrosil de trans-Tetrakispiridina de rutênio
The complexes trans-[RuCl2(L)4] (L = py, isn, 4-acpy e 3-acpy), trans-[RuCl(NO)(L)4](PF6)2 (L = py, isn e 4-acpy), trans-[Ru(OH)(NO)(py)4](PF6)2, trans-[RuCl(NO)(py)4]Cl23H2O, trans-[Ru(OH)(NO)(py)4]Cl2, cis-[RuCl2(DMSO)4], trans-[Ru(NO2)2(py)4], trans-[RuCl(NO2)(py)4], trans-[RuCl(acn)(py)4](PF6) and the reduced complex trans-[RuCl(NO)(py)4]I were synthesiz
Publicado em: 2009
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8. Dissociation of HNO and NO: leishmanicidal activity of nitrosil of ruthenium / Liberação de HNO e NO por nitrosilos de rutênio e sua atividade antileishmania
Ruthenium complexes type trans-[RuNO(NH3)4L](X)3 (X = BF4- or PF6- and L = imN, 4-pic, isn, py, pz, L- hist, nic, imC, P(OEt)3, SO32-), and [RuNO(Hedta)] were tested as antiproliferative agents against the Leishmania major parasite. The complexes where L = imN, pz, 4-pic, py, isn, and P(OEt)3 exhibited IC50pro ranging from 36 for trans-[RuNO(NH3)4imN](BF4)3
Publicado em: 2009
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9. Estudo das propriedades antioxidantes de complexos nitrosilados de rutênio
This study shows the antioxidant and secondary the cytotoxic activity of five different ruthenium nitrosyl complexes: trans-[Ru(NH3)4(L)(NO)]Cl3 (A - D; being (A) L = Caffeine, (B) L = Theophylline, (C) L = Methyl-1-imidazole, (D) L = Benzoimidazole), and (E) cis-[Ru(NH3)4(NO)2]Cl3. Only the complex (A) (L = Caffeine) presented significant reactivity identif
Publicado em: 2009
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10. Nitrosilo complexos de rutênio : síntese, caracterização e avaliação de suas potencialidades citotóxicas / Nitrosyl ruthenium complexes : synthesis, characterization and evaluation of its cytotoxic potentialities
The behavior of nitric oxide (NO) in biological systems has been under intense investigation in recent years in view of its possibly crucial role in a variety of physiological processes. Great progress in this area has been achieved by studying nitrosyl transition metal complexes. In this sense ruthenium complexes are by far the most studied and their relati
Publicado em: 2008
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11. Aspectos químicos e fotoquímicos de liberação controlada de óxido nítrico a partir de complexos nitrosilos de rutênio: ensaios farmacológicos e de citotoxicidade. / Chemical and photochemical aspects of control nitric oxide release from nitrosyl ruthenium complexes: pharmacological and cytotoxic assays.
Nitric oxide (NO) is a multipurpose biological agent that shows important role in brain, arteries, immunological system, liver and lungs. The NO basal level alterations have correlation with several diseases as hypertension, cancer, Raymonds disease and platelet aggregation. Aiming supply this deficient NO level, it was necessary propose new compounds that c
Publicado em: 2008
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12. Ruthenium nitrosyl compounds. Chemical equilibrium, involvement in vegetal systems and cytotoxicity in cancer / Nitrosilos complexos de rutênio. Equilíbrio químico, envolvimento em sistemas vegetais e citotoxicidade em modelos de câncer
The product of the reaction of trans-[Ru(NH3)4P(OEt) 3H2O]2+ with nitrite ions depends on the hydrogenionic concentration of the medium. In solutions with pH > 10, the final compound is the trans-[Ru(NH3)4P(OEt) 3NO2]+ (1,1 x 103 M-1.s-1), wich is quantitatively converted into the trans-[Ru(NH3)4P(OEt) 3NO]3+ in acid solutions (CH+ > 10-5 mol.L-1; kobs
Publicado em: 2008