Nitric Oxide Synthase Type Ii
Mostrando 1-12 de 33 artigos, teses e dissertações.
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1. Effects of Cinnamomum cassia extract on oxidative stress, immunreactivity of iNOS and impaired thoracic aortic reactivity induced by type II diabetes in rats
Type II diabetes is known to cause neuropathy, nephropathy and retinopathy. However, cardiovascular disorders associated with diabetes have been ignored. In traditional medicine, cinnamon (Cinnamomum cassia) bark has been used for its abilities to relieve fever, inflammation and chronic bronchitis. In the present study, the effect of Cinnamomum cassia extrac
Braz. J. Pharm. Sci.. Publicado em: 29/11/2018
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2. Células dendríticas plasmocitoides, dendrócitos dérmicos fator XIIIa positivos, macrófagos e expressão da forma induzida da óxido nítrico sintase na resposta tecidual cutânea de leishmaniose tegumentar americana / Plasmacytoid dendritic cells, Factor XIIIa-positive dermal dendrocytes, macrophages and inducible nitric oxide synthase expression in American tegumentary leishmaniasis skin lesions
Em todas as formas clínicas da leishmaniose tegumentar americana os macrófagos são as células efetoras mais importantes na destruição do parasita intracelular. As células dendríticas são células apresentadoras de antígeno localizadas nos sítios de inoculação, como pele e mucosa. Os dendrócitos dérmicos Fator XIIIa positivos são células deri
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 10/08/2012
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3. Contrasting effects of nitric oxide and corticotropin- releasing factor within the dorsal periaqueductal gray on defensive behavior and nociception in mice
The anxiogenic and antinociceptive effects produced by glutamate N-methyl-D-aspartate receptor activation within the dorsal periaqueductal gray (dPAG) matter have been related to nitric oxide (NO) production, since injection of NO synthase (NOS) inhibitors reverses these effects. dPAG corticotropin-releasing factor receptor (CRFr) activation also induces anx
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-04
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4. Autonomic function and vascular reactivity in first-degree relatives of subjects with type 2 diabetes and subjects with the 894G>T polimorphism of the endothelial nitric oxide synthase / Função autonômica e reatividade vascular em indivíduos com parentesco de diabetes tipo 2 e em portadores do polimorfismo 894G>T da óxido nítrico sintase endotelial
As doenças cardiovasculares estão entre as principais causas de mortalidade em muitos países. O sistema nervoso autônomo e a função endotelial constituem mecanismos centrais no desenvolvimento e progressão de doenças cardiovasculares. A função autonômica e a reatividade vascular podem estar alteradas em indivíduos com maior risco para doença car
Publicado em: 2009
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5. Sex differences in angiotensin II- induced hypertension
Sex differences in the development of hypertension and cardiovascular disease have been described in humans and in animal models. In this paper we will review some of our studies which have as their emphasis the examination of the role of sex differences and sex steroids in modulating the central actions of angiotensin II (ANG II) via interactions with free
Brazilian Journal of Medical and Biological Research. Publicado em: 26/03/2007
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6. Involvment of nitric oxide, prostaglandins and tumor necrosis factor on the development of ectopic endometrial implants (peritoneal) and its repercussions on pain and fertility in rats / Envolvimento de óxido nítrico, prostaglandinas e fator de necrose tumoral no desenvolvimento de implantes endometriais ectópicos (peritoneais) e suas repercussões sobre a dor e infertilidade em ratas
Endometriosis is a disease characterized by the presence of endometrial glands and stroma out of the uterine cavity and of the myometrium. It may cause tumor, pain (chronic pelvic pain, dyspareunia and dysmenorrhea) and infertility. Currently available evidence indicates that endometrial cells misplaced during menses into the peritoneal cavity in women with
Publicado em: 2005
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7. Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells.
Histochemical activity and immunoreactivity of nitric oxide synthase (NOS, EC 1.14.13.39) have been recently demonstrated in human lung epithelium. However, the molecular nature of NOS and the regulation and function of the enzyme(s) in the airway is not known. A549 cells (human alveolar type II epithelium-like), BEAS 2B cells (transformed human bronchial ep
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8. Neuronal (type I) nitric oxide synthase regulates nuclear factorκB activity and immunologic (type II) nitric oxide synthase expression
Nitric oxide subserves diverse physiologic roles in the nervous system. NO is produced from at least three different NO synthase (NOS) isoforms: neuronal NOS (nNOS), endothelial NOS, and immunologic NOS (iNOS). We show that nNOS is the predominant isoform constitutively expressed in glia. NO derived from nNOS in glia inhibits the transcription factor nuclear
The National Academy of Sciences of the USA.
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9. Investigation of Role of Nitric Oxide in Protection from Bordetella pertussis Respiratory Challenge
The mechanism whereby whole-cell pertussis vaccines (WCV) confer protection against Bordetella pertussis is still not fully understood. We have previously reported that macrophage activation produced by vaccination with WCV is associated with induction of NO synthesis by macrophages in response to in vitro stimulation with B. pertussis antigens. To determine
American Society for Microbiology.
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10. Role of inducible nitric oxide synthase in regulation of pulmonary vascular tone in the late gestation ovine fetus.
Nitric oxide (NO) produced by NO synthase (NOS) modulates fetal pulmonary vascular tone and contributes to the fall in pulmonary vascular resistance (PVR) at birth. Although the inducible (type II) NOS isoform is present in human and rat fetal lungs, it is uncertain whether type II NOS activity contributes to vascular NO production in the fetal lung. To dete
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11. Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils
Eosinophil migration in vivo is markedly attenuated in rats treated chronically with the NO synthase (NOS) inhibitor Nω-nitro-l-arginine methyl ester (l-NAME). In this study, we investigated the existence of a NOS system in eosinophils. Our results demonstrated that rat peritoneal eosinophils strongly express both type II (30.2 ± 11.6% of counted cells) an
The National Academy of Sciences of the USA.
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12. Inducible Nitric Oxide Synthase and Nitrotyrosine Are Found in Monocytes/Macrophages and/or Astrocytes in Acute, but Not in Chronic, Multiple Sclerosis
We have examined the localization of inducible nitric oxide synthase (iNOS) and nitrotyrosine (the product of nitration of tyrosine by peroxynitrite, a highly reactive derivative of nitric oxide [NO]) in demyelinating lesions from (i) two young adult patients with acute multiple sclerosis (MS), (ii) a child with MS (consistent with diffuse sclerosis), and (i
American Society for Microbiology.