Ngn
Mostrando 13-24 de 46 artigos, teses e dissertações.
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13. Modelos de faturamento em telecomunicações decorrentes da convergência de redes e serviços. / Telecom billing models for convergent networks and services.
O setor de Telecomunicações está mudando seus paradigmas em decorrência das tecnologias que utilizam o Protocolo Internet (IP). Essa tecnologia está cada vez mais permeando as redes de Telecomunicações, criando as chamadas Redes de Nova Geração (NGN). A convergência de redes e serviços está modificando as cadeias de valor em Telecomunicações, c
Publicado em: 2007
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14. Fertilidade de gemas de videiras 'Niagara Rosada' de acordo com o sistema de condução
O experimento teve por objetivo avaliar a influência dos sistemas de condução espaldeira e pérgula, na fertilidade das gemas da videira ' Niagara Rosada' na Região de Dourados-MS, durante o período de maio a junho de 2004. Coletaram-se bacelos provenientes de 24 vinhedos de plantas da cultivar Niagara Rosada enxertadas sobre o porta-enxerto IAC 572 'Ja
Revista Brasileira de Fruticultura. Publicado em: 2006-04
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15. Análise da evolução dos sistemas de telecomunicações móvel e fixo no Brasil e desenvolvimento de uma proposta para a prestação de serviço convergente / Analysis of the evolution of mobile and fixed telecommunications systems in brazil, developing a proposal for convergent service.
Os Sistemas e Serviços de Telecomunicações móveis apresentaram uma evolução de dimensão inaudita durante a última década, tornando-se ponto de referência para o desenvolvimento de aplicações para os usuários e soluções tecnológicas para a transferência de informação na rede. Paralelamente a esta evolução, o desenvolvimento tecnológico c
Publicado em: 2006
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16. Pancreatic neurogenin 3-expressing cells are unipotent islet precursors
Pancreatic islet endocrine cells arise during development from precursors expressing neurogenin 3 (Ngn3). As a population, Ngn3+ cells produce all islet cell types, but the potential of individual Ngn3+ cells, an issue central to organogenesis in general and to in vitro differentiation towards cell-based therapies, has not been addressed. We performed i
Company of Biologists.
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17. A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons
Neurogenin1 (Ngn1), Neurogenin2 (Ngn2), and Mash1 encode bHLH transcription factors with neuronal determination functions. In the telencephalon, the Ngns and Mash1 are expressed at high levels in complementary dorsal and ventral domains, respectively. We found that Ngn function is required to maintain these two separate expression domains, as Mash1 expressio
Cold Spring Harbor Laboratory Press.
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18. Proendocrine genes coordinate the pancreatic islet differentiation program in vitro
In the developing pancreas, the basic helix–loop–helix (bHLH) protein Neurogenin3 (Ngn3) specifies which precursor cells ultimately will become endocrine cells and initiates the islet differentiation program. NeuroD1, a closely related bHLH protein and a downstream target of Ngn3, maintains the differentiation program initiated by Ngn3. We have developed
National Academy of Sciences.
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19. neurogenin2 elicits the genesis of retinal neurons from cultures of nonneural cells
neurogenin2 (ngn2) encodes a basic helix–loop–helix transcription factor and plays an important role in neurogenesis from migratory neural crest cells. Its role in retinal development is poorly understood. We observed that in the developing chick retina, ngn2 was expressed in a subpopulation of proliferating progenitor cells. Ectopic expression of
The National Academy of Sciences.
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20. Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identity
The neural bHLH genes Mash1 and Ngn2 are expressed in complementary populations of neural progenitors in the central and peripheral nervous systems. Here, we have systematically compared the activities of the two genes during neural development by generating replacement mutations in mice in which the coding sequences of Mash1 and Ngn2 were swapped. Using thi
Cold Spring Harbor Laboratory Press.
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21. Ubiquitylation on Canonical and Non-canonical Sites Targets the Transcription Factor Neurogenin for Ubiquitin-mediated Proteolysis*
Polyubiquitylation targets multiple proteins for degradation by the proteasome. Typically, the first ubiquitin is linked to lysine residues in the substrate for degradation via an isopeptide bond, although rarely ubiquitin linkage to the N-terminal residue has also been observed. We have recently shown that Neurogenin (NGN), a basic helix-loop-helix transcri
American Society for Biochemistry and Molecular Biology.
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22. Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium
Endocrine cells of the pancreas and the gastrointestinal tract derive from multipotent endodermal stem cells. We have shown previously that the basic helix– loop–helix (bHLH) transcription factor neurogenin3 (ngn3) is required for the specification of the endocrine lineage in uncommitted progenitors in the developing pancreas. We investigate herein the e
Oxford University Press.
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23. Regulation of the Pancreatic Islet-Specific Gene BETA2 (neuroD) by Neurogenin 3
The BETA2 (neuroD) gene is expressed in endocrine cells during pancreas development and is essential for proper islet morphogenesis. The objective of this study is to identify potential upstream regulators of the BETA2 gene during pancreas development. We demonstrated that the expression of neurogenin 3 (ngn3), an islet- and neuron-specific basic-helix-loop-
American Society for Microbiology.
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24. neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
In the mammalian pancreas, the endocrine cell types of the islets of Langerhans, including the α-, β-, δ-, and pancreatic polypeptide cells as well as the exocrine cells, derive from foregut endodermal progenitors. Recent genetic studies have identified a network of transcription factors, including Pdx1, Isl1, Pax4, Pax6, NeuroD, Nkx2.2, and Hlxb9, regula
The National Academy of Sciences.