Nfkb
Mostrando 13-24 de 176 artigos, teses e dissertações.
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13. Atividade Inflamatória Persistente em Células Circulantes e Tecido Arterial de Pacientes com Stent Convencional Prévio
Resumo Fundamento: Estudos relataram maior mortalidade após cirurgia de revascularização miocárdica (RVM) em pacientes com stent. Objetivo: Avaliar marcadores inflamatórios em células do sangue periférico e em amostras de tecido de artéria coronária obtidas durante cirurgia de RVM em pacientes com stent e compará-los aos de controles. Métodos:
Arq. Bras. Cardiol.. Publicado em: 16/07/2018
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14. Immunhistochemical analysis of Nuclear Factor Kappa Beta expression in etiopathogenesis of ovarian tumors
Abstract Purpose: To investigate the place of the transcription factor nuclear kappa B (NF-kB), which is a marker of chronic inflammation, in the etiology of the ovarian carcinoma. Methods: NFkB analysis with the immunohistochemical method has been performed. To evaluate immunohistochemical NF-kB expression in the ovarian tissue, the H-score method. H-scor
Acta Cir. Bras.. Publicado em: 2018-07
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15. NF-kB mediated CX3CL1 activation in the dorsal root ganglion contributes to the maintenance of neuropathic pain induced in adult male Sprague Dawley rats
Abstract Purpose: To evaluate the role of CX3CL1 and NF-κB in the lumbar disc herniation induced neuropathic pain. Methods: After LDH induced by implantation of autologous nucleus pulposus (NP) on the left L5 nerve root was established, mechanical thresholds and thermal hyperalgesia were tested at relevant time points during an observation period of 28
Acta Cir. Bras.. Publicado em: 2018-07
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16. Effects of baicalin on inflammatory reaction, oxidative stress and PKDl and NF-kB protein expressions in rats with severe acute pancreatitis
Abstract Purpose: To investigate the effects of baicalin on inflammatory reaction, oxidative stress and protein kinase D1 (PKD1) and nuclear factor-kappa B (NF-κB) protein expressions in severe acute pancreatitis (SAP) rats. Methods: Sixty rats were divided into sham operation, model, and low-, medium- and high-dose baicalin group. SAP model was establis
Acta Cir. Bras.. Publicado em: 2018-07
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17. Effects of triethylene glycol dimethacrylate (TEGDMA) on the odontoclastic differentiation ability of human dental pulp cells
Abstract Objectives: The primary purpose of this study was to examine the effects of triethylene glycol dimethacrylate (TEGDMA) on odontoclastic differentiation in the dental pulp tissue. Material and Methods: The effects of different TEGDMA dosages on the odontoclastic differentiation capability of dental pulp cells were analyzed in vitro using the follow
J. Appl. Oral Sci.. Publicado em: 2017-12
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18. Himatanthus drasticus: a chemical and pharmacological review of this medicinal species, commonly found in the Brazilian Northeastern region
ABSTRACT In order to compile the empirical use, as well as the chemical, pharmacological and biological aspects of Himatanthus drasticus (Mart.) Plumel, Apocynaceae, a review was carried out by searching PubMed, Google Scholar, Scientific Electronic Online Library, Web of Science, Science Direct, Scopus and Cochrane. For that, works in English, Spanish and P
Rev. bras. farmacogn.. Publicado em: 2017-12
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19. Alterações intestinais inflamatórias e de estresse oxidativo em modelo experimental de hipertensão portal: ação da N-acetilcisteína
RESUMO Introdução: A Hipertensão Portal (HP) é caracterizada por uma vasodilatação no sistema portal, e o intestino é um dos órgãos gravemente acometidos. A N-acetilcisteína (NAC) é uma molécula com importantes propriedades, amplamente utilizada na clínica. Objetivo: Avaliar a ação da NAC no intestino de animais submetidos ao modelo animal d
J. Coloproctol. (Rio J.). Publicado em: 2016-12
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20. Potential therapeutic strategies for non - muscle invasive bladder cancer based on association of intravesical immunotherapy with P-MAPA and systemic administration of cisplatin and doxorubicin
ABSTRACT The present study describes the histopathological and molecular effects of P-MAPA (Protein aggregate magnesium-ammonium phospholinoleate-palmitoleate anhydride) intravesical immunotherapy combined with systemic doxorubicin or cisplatin for treatment of non-muscle invasive bladder cancer (NMIBC) in an appropriate animal model. Our results showed an u
Int. braz j urol.. Publicado em: 2016-10
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21. Efeito antioxidante da mesalazina no modelo de colite experimental induzida por ácido acético
Resumo Introdução A doença inflamatória intestinal (DII) caracteriza-se por uma inflamação crônica do trato gastrointestinal sem uma causa ou patógeno específico. Objetivo Foi avaliado o efeito da mesalazina no modelo de colite induzida por ácido acético (AA). Material e métodos Foram utilizados 40 ratos wistar, ±350 gramas, divididos em 4 gr
J. Coloproctol. (Rio J.). Publicado em: 2016-09
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22. Down-Regulation of NFkB, Bax,TGF-β, Smad-2mRNA expression in the Livers of Carbon Tetrachloride Treated Rats using Different Natural Antioxidants
The objective of this study is to examine whether silymarin alone or in combination with chlorogenic acid and/ or melatonin plays a modulatory role against apoptotic damage in rats liver induced by of CCl4. The present work revealed that CCl4 induced elevation of in Bax, Smad, TGF-β and NFkBhepatic mRNA expression, administration of silymarin alone down reg
Braz. arch. biol. technol.. Publicado em: 22/03/2016
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23. Six-week anaerobic training improves proteolytic profile of diabetic rats
Objective To evaluate the effect of six-week anaerobic training on the mRNA expression of genes related to proteolysis Ubb (Ubiquitin), E2-14kDa, Trim63 (MuRF1 protein) and Nfkb1 in the skeletal muscle of diabetic rats.Materials and methods Four groups were established: DE (DiabetesExercised), DS (Diabetes Sedentary), CE (Control Exercised) and CS (Control S
Arch. Endocrinol. Metab.. Publicado em: 25/09/2015
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24. Efeitos de extrato de canela sobre os níveis de enzimas bioquímicos, e expressão de genes de TNF-α e NF-κB em fígado de frangos de corte inoculadas com Escherichia coli
Resumo: Infecção ocasionada por Escherichia coli (E. coli) é uma enfermidade comum na indústria avícola. O uso de antibióticos para tratar doenças bacterianas vem enfrentando sérias críticas e preocupações. As plantas medicinais podem ser alternativas eficazes por causa de suas atividades sinérgicas. O objetivo deste estudo foi investigar os efei
Pesq. Vet. Bras.. Publicado em: 2015-09